Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice (Q30483008)

16 August 2017

Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice (English)

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arteriovenous malformation

16 August 2017

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Patrick A Murphy

1

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16 August 2017

Michael T Y Lam

2

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16 August 2017

Xiaoqing Wu

3

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16 August 2017

Tyson N Kim

4

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16 August 2017

Shant M Vartanian

5

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16 August 2017

Andrew W Bollen

6

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16 August 2017

Timothy R Carlson

7

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16 August 2017

Rong A Wang

8

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16 August 2017

language of work or name

English

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publication date

30 July 2008

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Proceedings of the National Academy of Sciences of the United States of America

16 August 2017

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16 August 2017

105

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16 August 2017

31

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16 August 2017

10901-10906

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Cell-autonomous requirement for beta1 integrin in endothelial cell adhesion, migration and survival during angiogenesis in mice

16 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Clinical practice. Arteriovenous malformations of the brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Ephrin-B2 forward signaling regulates somite patterning and neural crest cell development

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

The Physiological Principle of Minimum Work: I. The Vascular System and the Cost of Blood Volume

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Invasive treatment of unruptured brain arteriovenous malformations is experimental therapy.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Hereditary haemorrhagic telangiectasia: current views on genetics and mechanisms of disease

20 June 2018

1 reference

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Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Notch signaling: control of cell communication and cell fate

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Spatially restricted patterning cues provided by heparin-binding VEGF-A control blood vessel branching morphogenesis

20 June 2018

1 reference

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Arteries and veins: making a difference with zebrafish

20 June 2018

1 reference

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Cancer. Addiction to oncogenes--the Achilles heal of cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Arteriovenous malformations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Notch signaling is required for arterial-venous differentiation during embryonic vascular development.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Potential role of modifier genes influencing transforming growth factor-beta1 levels in the development of vascular defects in endoglin heterozygous mice with hereditary hemorrhagic telangiectasia.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Reporting terminology for brain arteriovenous malformation clinical and radiographic features for use in clinical trials

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic mice

20 June 2018

1 reference

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Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Spontaneous obliteration of pial arteriovenous malformations: a review of 27 cases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Reversible tumorigenesis by MYC in hematopoietic lineages

20 June 2018

1 reference

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Conditional expression and signaling of a specifically designed Gi-coupled receptor in transgenic mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Molecular distinction and angiogenic interaction between embryonic arteries and veins revealed by ephrin-B2 and its receptor Eph-B4

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Embryological basis of some aspects of cerebral vascular fistulas and malformations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Matrix metalloproteinase-9 inhibition attenuates vascular endothelial growth factor-induced intracerebral hemorrhage

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Mapping postnatal mouse brain development with diffusion tensor microimaging

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

VEGF is crucial for the hepatic vascular development required for lipoprotein uptake

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Are there genetic influences on sporadic brain arteriovenous malformations?

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Doxycycline suppresses cerebral matrix metalloproteinase-9 and angiogenesis induced by focal hyperstimulation of vascular endothelial growth factor in a mouse model

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Cerebral vascular abnormalities in a murine model of hereditary hemorrhagic telangiectasia

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Differential effects of doxycycline, a broad-spectrum matrix metalloproteinase inhibitor, on angiotensin II-induced atherosclerosis and abdominal aortic aneurysms.

26 November 2018

1 reference

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A mouse model for hereditary hemorrhagic telangiectasia (HHT) type 2.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Diagnosis of an intracranial arteriovenous malformation using extracranial carotid Doppler sonography.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2504798

Angiographic and clinical characteristics of patients with cerebral arteriovenous malformations associated with hereditary hemorrhagic telangiectasia

26 November 2018

1 reference

12 December 2020

Recommendations for the management of intracranial arteriovenous malformations: a statement for healthcare professionals from a special writing group of the Stroke Council, American Stroke Association

1 reference

12 December 2020

Determination of cerebral blood flow with a phase-contrast cine MR imaging technique: evaluation of normal subjects and patients with arteriovenous malformations

1 reference

12 December 2020

Cerebrovascular manifestations in 321 cases of hereditary hemorrhagic telangiectasia

1 reference

12 December 2020

Ultrastructure and three-dimensional organization of the telangiectases of hereditary hemorrhagic telangiectasia

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0802743105

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16 August 2017

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16 August 2017

PubMed publication ID

18667694

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