Determination of solution conformations of PrP106-126, a neurotoxic fragment of prion protein, by 1H NMR and restrained molecular dynamics. (Q30585001)

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2 November 2019

title

Determination of solution conformations of PrP106-126, a neurotoxic fragment of prion protein, by 1H NMR and restrained molecular dynamics (English)

1 reference

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molecular dynamics simulation

2 November 2019

main subject

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0 references

1 reference

1

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2 November 2019

Luca Monticelli

4

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2 November 2019

Mario Salmona

7

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2 November 2019

author name string

F Tagliavini

2

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2 November 2019

P Malesani

3

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2 November 2019

O Bugiani

5

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2 November 2019

G Forloni

6

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2 November 2019

language of work or name

English

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publication date

1 December 1999

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2 November 2019

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2 November 2019

volume

266

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2 November 2019

issue

3

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2 November 2019

page(s)

1192-1201

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NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231).

2 November 2019

cites work

1 reference

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NMR structure of the mouse prion protein domain PrP(121-231)

21 January 2018

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Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible

21 January 2018

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Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

21 January 2018

1 reference

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Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro

21 January 2018

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Channel formation by a neurotoxic prion protein fragment

21 January 2018

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Prion protein peptides induce alpha-helix to beta-sheet conformational transitions

21 January 2018

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Molecular characteristics of a protease-resistant, amyloidogenic and neurotoxic peptide homologous to residues 106-126 of the prion protein

21 January 2018

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Identification of a protein that purifies with the scrapie prion

21 January 2018

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Neurotoxicity of a prion protein fragment

21 January 2018

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A neurotoxic prion protein fragment induces rat astroglial proliferation and hypertrophy.

21 January 2018

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Role of microglia and host prion protein in neurotoxicity of a prion protein fragment

21 January 2018

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Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

21 January 2018

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Determination of three-dimensional structures of proteins from interproton distance data by dynamical simulated annealing from a random array of atoms. Circumventing problems associated with folding

21 January 2018

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Chemical shifts as a tool for structure determination

21 January 2018

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1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects

21 January 2018

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Conformational behavior of Escherichia coli OmpA signal peptides in membrane mimetic environments

21 January 2018

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NMR evidence for multiple conformations in a highly helical model peptide.

21 January 2018

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Nuclear-magnetic-resonance study on Met-enkephalin and Met-enkephalinamide. Molecular association and conformation

21 January 2018

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Elucidating the folding problem of helical peptides using empirical parameters

21 January 2018

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Folding of immunogenic peptide fragments of proteins in water solution. I. Sequence requirements for the formation of a reverse turn

21 January 2018

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Folding of immunogenic peptide fragments of proteins in water solution. II. The nascent helix

21 January 2018

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Calibration of the angular dependence of the amide proton-C alpha proton coupling constants, 3JHN alpha, in a globular protein. Use of 3JHN alpha for identification of helical secondary structure

21 January 2018

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Predicted alpha-helical regions of the prion protein when synthesized as peptides form amyloid

21 January 2018

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Scrapie prions: a three-dimensional model of an infectious fragment

21 January 2018

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Conformational transitions in peptides containing two putative alpha-helices of the prion protein.

21 January 2018

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Alternative conformations of amyloidogenic proteins govern their behavior

21 January 2018

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The solution structure of serine protease PB92 from Bacillus alcalophilus presents a rigid fold with a flexible substrate-binding site

21 January 2018

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The high-resolution X-ray crystal structure of the complex formed between subtilisin Carlsberg and eglin c, an elastase inhibitor from the leech Hirudo medicinalis. Structural analysis, subtilisin structure and interface geometry

21 January 2018

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Solution structure of Syrian hamster prion protein rPrP(90-231).

21 January 2018

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A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform

21 January 2018

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A transmembrane form of the prion protein in neurodegenerative disease

21 January 2018

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Charged histidine affects alpha-helix stability at all positions in the helix by interacting with the backbone charges

21 January 2018

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Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred

21 January 2018

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Homozygous prion protein genotype predisposes to sporadic Creutzfeldt–Jakob disease

21 January 2018

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Genetic predisposition to iatrogenic Creutzfeldt-Jakob disease

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