CRISPR-Cas9 knockin mice for genome editing and cancer modeling (Q30607892)

18 October 2017

CRISPR-Cas9 knockin mice for genome editing and cancer modeling (English)

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18 October 2017

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Siddharth Jhunjhunwala

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18 October 2017

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Nir Hacohen

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Robert S. Langer, Jr.

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object named as

Robert Langer

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Ramnik J Xavier

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18 October 2017

Randall J Platt

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Sidi Chen

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18 October 2017

Yang Zhou

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Michael J Yim

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Lukasz Swiech

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Hannah R Kempton

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James E Dahlman

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Oren Parnas

8

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Thomas M Eisenhaure

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Marko Jovanovic

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Daniel B Graham

11

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Matthias Heidenreich

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Daniel G Anderson

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Guoping Feng

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Phillip A Sharp

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18 October 2017

Feng Zhang

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18 October 2017

language of work or name

English

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publication date

25 September 2014

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18 October 2017

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159

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2

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18 October 2017

440-455

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describes a project that uses

18 October 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4265475/fullTextXML

inferred from PubMed Central ID database lookup

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CRISPR-mediated direct mutation of cancer genes in the mouse liver

20 June 2018

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20 June 2018

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Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing

20 June 2018

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Development and applications of CRISPR-Cas9 for genome engineering

20 June 2018

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Global microRNA depletion suppresses tumor angiogenesis.

20 June 2018

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20 June 2018

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Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype.

20 June 2018

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Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library

20 June 2018

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Genome-scale CRISPR-Cas9 knockout screening in human cells

20 June 2018

1 reference

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Genetic screens in human cells using the CRISPR-Cas9 system

20 June 2018

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An in vivo RNAi screening approach to identify host determinants of virus replication

20 June 2018

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RNAi screens in mice identify physiological regulators of oncogenic growth

20 June 2018

1 reference

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Optical control of mammalian endogenous transcription and epigenetic states

20 June 2018

1 reference

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DNA targeting specificity of RNA-guided Cas9 nucleases

20 June 2018

1 reference

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Mutational heterogeneity in cancer and the search for new cancer-associated genes

20 June 2018

1 reference

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Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells

20 June 2018

1 reference

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Lessons from the cancer genome

20 June 2018

1 reference

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RNA-guided human genome engineering via Cas9

20 June 2018

1 reference

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Multiplex genome engineering using CRISPR/Cas systems

20 June 2018

1 reference

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Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

20 June 2018

1 reference

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A high-throughput chromatin immunoprecipitation approach reveals principles of dynamic gene regulation in mammals

20 June 2018

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NIH Image to ImageJ: 25 years of image analysis

20 June 2018

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

20 June 2018

1 reference

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Ciliated adenocarcinomas of the lung: a tumor of non-terminal respiratory unit origin

20 June 2018

1 reference

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An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration

20 June 2018

1 reference

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VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

20 June 2018

1 reference

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Systematic discovery of TLR signaling components delineates viral-sensing circuits

20 June 2018

1 reference

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The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli

20 June 2018

1 reference

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The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice

20 June 2018

1 reference

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Optimizing promoters for recombinant adeno-associated virus-mediated gene expression in the peripheral and central nervous system using self-complementary vectors

20 June 2018

1 reference

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CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

20 June 2018

1 reference

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The CRISPR/Cas bacterial immune system cleaves bacteriophage and plasmid DNA

20 June 2018

1 reference

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Fast and accurate long-read alignment with Burrows-Wheeler transform

20 June 2018

1 reference

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A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

20 June 2018

1 reference

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Effect of genome size on AAV vector packaging

20 June 2018

1 reference

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Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses

20 June 2018

1 reference

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Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

20 June 2018

1 reference

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20 June 2018

1 reference

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Direct multiplexed measurement of gene expression with color-coded probe pairs

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

Adeno-associated virus serotype 9 vectors transduce murine alveolar and nasal epithelia and can be readministered.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

A developmental switch in the response of DRG neurons to ETS transcription factor signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

Enhancing Gene Targeting with Designed Zinc Finger Nucleases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

Systematic determination of the packaging limit of lentiviral vectors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

Conditional control of gene expression in the mouse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

Dendritic cells: specialized and regulated antigen processing machines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

Stimulation of homologous recombination through targeted cleavage by chimeric nucleases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

High frequency of homologous recombination in mammalian cells between endogenous and introduced SV40 genomes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

Genetic and physical analysis of double-strand break repair and recombination in Saccharomyces cerevisiae.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

Direct in vivo RNAi screen unveils myosin IIa as a tumor suppressor of squamous cell carcinomas

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

Transgenic expression of Cre recombinase from the tyrosine hydroxylase locus

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

Efficient mouse airway transduction following recombination between AAV vectors carrying parts of a larger gene.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

Analysis of Fgf8 gene function in vertebrate development

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265475

In vivo measurement of lung volumes in mice

25 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25263330

12 December 2020

inferred from PubMed ID database lookup

The immunogenicity of adenovirus vectors limits the multispecificity of CD8 T-cell responses to vector-encoded transgenic antigens

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25263330

12 December 2020

inferred from PubMed ID database lookup

Flow cytometric sorting of neuronal and glial nuclei from central nervous system tissue

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25263330

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.CELL.2014.09.014

1 reference

18 October 2017

1 reference

18 October 2017

PubMed publication ID

25263330

1 reference