Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein (Q30725106)

26 June 2017

title

Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein (English)

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26 June 2017

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P L Opresko

1

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26 June 2017

J P Laine

2

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26 June 2017

R M Brosh

3

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26 June 2017

M M Seidman

4

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26 June 2017

V A Bohr

5

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26 June 2017

language of work or name

English

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publication date

25 September 2001

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Journal of Biological Chemistry

26 June 2017

published in

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26 June 2017

volume

276

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26 June 2017

issue

48

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26 June 2017

page(s)

44677-44687

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Genetic analysis of ageing: role of oxidative damage and environmental stresses.

26 June 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M107548200

Positional cloning of the Werner's syndrome gene

21 January 2018

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The Werner syndrome protein is a DNA helicase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107548200

The premature ageing syndrome protein, WRN, is a 3'-->5' exonuclease

21 January 2018

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Characterization of Werner syndrome protein DNA helicase activity: directionality, substrate dependence and stimulation by replication protein A

21 January 2018

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Enzymatic and DNA binding properties of purified WRN protein: high affinity binding to single-stranded DNA but not to DNA damage induced by 4NQO.

21 January 2018

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The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase

21 January 2018

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Molecular genetics of Bloom's syndrome

21 January 2018

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Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107548200

The Werner syndrome protein: an update

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107548200

Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines

21 January 2018

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An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants

21 January 2018

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Mutator phenotype of Werner syndrome is characterized by extensive deletions

21 January 2018

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Werner syndrome protein: biochemical properties and functional interactions

21 January 2018

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DNA damage and repair in telomeres: relation to aging

21 January 2018

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The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107548200

Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107548200

Functional and physical interaction between WRN helicase and human replication protein A

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107548200

A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107548200

Characterization of the human and mouse WRN 3'-->5' exonuclease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107548200

Werner syndrome exonuclease catalyzes structure-dependent degradation of DNA.

21 January 2018

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Ku, a DNA repair protein with multiple cellular functions?

21 January 2018

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Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks

21 January 2018

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Selective blockage of the 3'-->5' exonuclease activity of WRN protein by certain oxidative modifications and bulky lesions in DNA.

21 January 2018

1 reference

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Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex

21 January 2018

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Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M107548200

Mechanisms of helicase-catalyzed DNA unwinding

21 January 2018

1 reference

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DNA helicases: 'inching forward'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Binding and melting of D-loops by the Bloom syndrome helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Ku binds telomeric DNA in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Mammalian telomeres end in a large duplex loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Characterization of genetic interactions with RFA1: the role of RPA in DNA replication and telomere maintenance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

The Saccharomyces cerevisiae WRN homolog Sgs1p participates in telomere maintenance in cells lacking telomerase

21 January 2018

1 reference

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Werner syndrome protein. II. Characterization of the integral 3' --> 5' DNA exonuclease

21 January 2018

1 reference

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Chromosome instability in lymphocytes from a patient with Werner's syndrome is not associated with DNA repair defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Unwinding of a DNA triple helix by the Werner and Bloom syndrome helicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

Human werner syndrome DNA helicase unwinds tetrahelical structures of the fragile X syndrome repeat sequence d(CGG)n

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107548200

21 January 2018

Identifiers

DOI

10.1074/JBC.M107548200

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26 June 2017

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