Modelling Ser129 phosphorylation inhibits membrane binding of pore-forming alpha-synuclein oligomers (Q31165000)

20 September 2017

Modelling Ser129 phosphorylation inhibits membrane binding of pore-forming alpha-synuclein oligomers (English)

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20 September 2017

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8

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20 September 2017

2

Johannes Levin

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20 September 2017

Georg Sebastian Nübling

1

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20 September 2017

Benedikt Bader

3

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20 September 2017

Stefan Lorenzl

4

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20 September 2017

Andreas Hillmer

5

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20 September 2017

Tobias Högen

6

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20 September 2017

Frits Kamp

7

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20 September 2017

language of work or name

English

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publication date

9 June 2014

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20 September 2017

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20 September 2017

9

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20 September 2017

6

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20 September 2017

e98906

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Creative Commons Attribution 4.0 International

20 September 2017

start time

9 June 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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α-Synuclein oligomers: an amyloid pore? Insights into mechanisms of α-synuclein oligomer-lipid interactions

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Single-channel electrophysiology reveals a distinct and uniform pore complex formed by α-synuclein oligomers in lipid membranes

21 June 2018

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21 June 2018

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Two different binding modes of α-synuclein to lipid vesicles depending on its aggregation state

21 June 2018

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Phosphorylation of α-synuclein protein at Ser-129 reduces neuronal dysfunction by lowering its membrane binding property in Caenorhabditis elegans

21 June 2018

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Contribution of Alanine-76 and Serine Phosphorylation in α-Synuclein Membrane Association and Aggregation in Yeasts

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The N-Terminus of the Intrinsically Disordered Protein α-Synuclein Triggers Membrane Binding and Helix Folding

21 June 2018

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Inhibition of mitochondrial fusion by α-synuclein is rescued by PINK1, Parkin and DJ-1.

21 June 2018

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Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions

21 June 2018

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Tryptophan fluorescence reveals structural features of alpha-synuclein oligomers

21 June 2018

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Dietary iron intake and risk of Parkinson's disease

21 June 2018

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Formation of toxic oligomeric alpha-synuclein species in living cells

21 June 2018

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The phosphorylation state of Ser-129 in human alpha-synuclein determines neurodegeneration in a rat model of Parkinson disease

21 June 2018

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21 June 2018

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The role of alpha-synuclein in neurodegenerative diseases

21 June 2018

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Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration

21 June 2018

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Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 June 2018

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21 June 2018

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Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

21 June 2018

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Membrane association and protein conformation of alpha-synuclein in intact neurons. Effect of Parkinson's disease-linked mutations

21 June 2018

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Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein

21 June 2018

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Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation.

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Mechanism of membrane interaction and disruption by α-synuclein.

21 January 2018

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Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease

21 January 2018

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AMPA-receptor-mediated excitatory synaptic transmission is enhanced by iron-induced α-synuclein oligomers

21 January 2018

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Phosphorylation sensitizes microtubule-associated protein tau to Al(3+)-induced aggregation

21 January 2018

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Alpha-synuclein has a high affinity for packing defects in a bilayer membrane: a thermodynamics study

21 January 2018

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Allostery in a disordered protein: oxidative modifications to α-synuclein act distally to regulate membrane binding

21 January 2018

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Binding of alpha-synuclein affects the lipid packing in bilayers of small vesicles

21 January 2018

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Generation of ferric iron links oxidative stress to α-synuclein oligomer formation

21 January 2018

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Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain

31 October 2018

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12 December 2020

Sequestration of iron by Lewy bodies in Parkinson's disease

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12 December 2020

Single particle analysis of tau oligomer formation induced by metal ions and organic solvents

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12 December 2020

Single particle detection and characterization of synuclein co-aggregation

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12 December 2020

Kinetic measurements give new insights into lipid membrane permeabilization by α-synuclein oligomers

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12 December 2020

A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in α-synuclein transgenic C . elegans

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12 December 2020

10.1371/JOURNAL.PONE.0098906

Identifiers

DOI

1 reference

20 September 2017

0 references

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20 September 2017

PubMed publication ID

24911099

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