The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease. (Q31744197)

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English	The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease.	scientific article

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3 November 2019

The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease (English)

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3 November 2019

Parkinson's disease

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M Thiruchelvam

1

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3 November 2019

E K Richfield

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3 November 2019

R B Baggs

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3 November 2019

A W Tank

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3 November 2019

D A Cory-Slechta

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3 November 2019

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1 December 2000

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3 November 2019

Journal of Neuroscience

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3 November 2019

20

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3 November 2019

24

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3 November 2019

9207-9214

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3 November 2019

Acute exposure to maneb alters some behavioral functions in the mouse

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Community exposure to a paraquat drift

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Microgliosis and down-regulation of adenosine transporter induced by methamphetamine in rats

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Dithiocarbamate pesticides affect glutamate transport in brain synaptic vesicles.

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Attenuation of the locomotor activating effects of D-amphetamine, cocaine, and scopolamine by potassium channel modulators.

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Effects of calcium channel entry blockers on cocaine and amphetamine-induced motor activities and toxicities.

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Disulfiram and Diethyldithiocarbamate Intoxication Affects the Storage and Release of Striatal Dopamine

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Pre- and postsynaptic neurotoxic effects of dopamine demonstrated by intrastriatal injection

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Role of oxidation in the neurotoxic effects of intrastriatal dopamine injections

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Selective vulnerability of pigmented dopaminergic neurons in Parkinson's disease

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Mechanism of cytotoxicity of paraquat. I. NADH oxidation and paraquat radical formation via complex I.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Long-term effects of amphetamine neurotoxicity on tyrosine hydroxylase mRNA and protein in aged rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Treatment of mice with methamphetamine produces cell loss in the substantia nigra

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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No changes in behaviour, nigro-striatal system neurochemistry or neuronal cell death following toxic multiple oral paraquat administration to rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Diethyldithiocarbamate causes nigral cell loss and dopamine depletion with nontoxic doses of MPTP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Excessive iron accumulation in the brain: a possible potential risk of neurodegeneration in Parkinson's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Parkinsonism after chronic exposure to the fungicide maneb (manganese ethylene-bis-dithiocarbamate)

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Parkinson's disease and exposure to agricultural work and pesticide chemicals

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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A mechanism of paraquat toxicity in mice and rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Iron metabolism and Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Parkinson disease in twins: an etiologic study

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Synergistic interactions between NADPH-cytochrome P-450 reductase, paraquat, and iron in the generation of active oxygen radicals

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Role for excitatory amino acids in methamphetamine-induced nigrostriatal dopaminergic toxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Influence of methamphetamine on nigral and striatal tyrosine hydroxylase activity and on striatal dopamine levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Effects of paraquat on the substantia nigra of the wistar rats: neurochemical, histological, and behavioral studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Evidence that paraquat is able to cross the blood-brain barrier to a different extent in rats of various age

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Multiple methamphetamine injections induce marked increases in extracellular striatal dopamine which correlate with subsequent neurotoxicity

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Toxicity of fungicides containing ethylene-bis-dithiocarbamate in serumless dissociated mesencephalic-striatal primary coculture

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Oxygen toxicity, oxygen radicals, transition metals and disease

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Epidemiology of Parkinson's disease

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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MPTP: current concepts and controversies

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Residues of four ethylenebis(dithiocarbamates) and their decomposition products on field-sprayed tomatoes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Vehicle alteration of paraquat lethality in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Dopamine turnover and glutathione oxidation: implications for Parkinson disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Induction of tyrosine hydroxylase protein and a transgene containing tyrosine hydroxylase 5' flanking sequences by stress in mouse adrenal gland

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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The effect of diethyldithiocarbamate on the biodisposition of MPTP: an explanation for enhanced neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: environmental risk factors for Parkinson's disease?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Maneb enhances MPTP neurotoxicity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Environmental risk factors and Parkinson's disease: a case-control study in Taiwan

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Mancozeb residues on field sprayed apricots

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Diethyldithiocarbamate potentiates the neurotoxicity of in vivo 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and of in vitro 1-methyl-4-phenylpyridinium

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Selective nigral toxicity after systemic administration of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyrine (MPTP) in the squirrel monkey

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Protection against paraquat-induced toxicity with sulfite or thiosulfate in mice

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Histochemical observations on rodent brain melanin

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Differential mechanisms in the effects of disulfiram and diethyldithiocarbamate intoxication on striatal release and vesicular transport of glutamate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic exposure to the fungicide maneb may produce symptoms and signs of CNS manganese intoxication.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Effects of paraquat on mitochondrial electron transport system and catecholamine contents in rat brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Geography, drinking water chemistry, pesticides and herbicides and the etiology of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Parkinson's disease: a case-control study of occupational and environmental risk factors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Influence of age on the passage of paraquat through the blood-brain barrier in rats: a distribution and pathological examination

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Neonatal exposure to paraquat or MPTP induces permanent changes in striatum dopamine and behavior in adult mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

based on heuristic

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Etiology and pathogenesis of Parkinson's disease

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https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/11124998

12 December 2020

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Identifiers

10.1523/JNEUROSCI.20-24-09207.2000

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11124998%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11124998%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11124998%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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