Differential processing of class-I-restricted epitopes by the standard proteasome and the immunoproteasome (Q32067271)

6 July 2017

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title

Differential processing of class-I-restricted epitopes by the standard proteasome and the immunoproteasome (English)

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6 July 2017

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Van den Eynde BJ

1

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6 July 2017

Morel S

series ordinal

2

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6 July 2017

publication date

1 April 2001

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Current Opinion in Immunology

6 July 2017

published in

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6 July 2017

volume

13

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6 July 2017

issue

2

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6 July 2017

page(s)

147-153

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Degradation of cell proteins and the generation of MHC class I-presented peptides

6 July 2017

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The proteasome: paradigm of a self-compartmentalizing protease

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7 January 2021

The MHC class I ligand-generating system: roles of immunoproteasomes and the interferon-gamma-inducible proteasome activator PA28.

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7 January 2021

The interferon-gamma-inducible 11 S regulator (PA28) and the LMP2/LMP7 subunits govern the peptide production by the 20 S proteasome in vitro

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7 January 2021

Altered properties of the branched chain amino acid-preferring activity contribute to increased cleavages after branched chain residues by the "immunoproteasome."

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Dendritic cells up-regulate immunoproteasomes and the proteasome regulator PA28 during maturation

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The formation of immunogenic major histocompatibility complex class II-peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli

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The subunits MECL-1 and LMP2 are mutually required for incorporation into the 20S proteasome

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Immunoproteasome assembly: cooperative incorporation of interferon gamma (IFN-gamma)-inducible subunits

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7 January 2021

Novel propeptide function in 20 S proteasome assembly influences beta subunit composition

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7 January 2021

Peptidase activities of proteasomes are differentially regulated by the major histocompatibility complex-encoded genes for LMP2 and LMP7.

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7 January 2021

Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands

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Impaired immunoproteasome assembly and immune responses in PA28-/- mice.

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7 January 2021

The function of the proteasome system in MHC class I antigen processing.

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7 January 2021

Overexpression of the proteasome subunits LMP2, LMP7, and MECL-1, but not PA28 alpha/beta, enhances the presentation of an immunodominant lymphocytic choriomeningitis virus T cell epitope

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7 January 2021

Differential influence on cytotoxic T lymphocyte epitope presentation by controlled expression of either proteasome immunosubunits or PA28

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7 January 2021

Replacement of proteasome subunits X and Y by LMP7 and LMP2 induced by interferon-gamma for acquirement of the functional diversity responsible for antigen processing

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7 January 2021

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7 January 2021

Altered peptidase and viral-specific T cell response in LMP2 mutant mice.

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7 January 2021

Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes

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7 January 2021

A tyrosinase peptide presented by HLA-B35 is recognized on a human melanoma by autologous cytotoxic T lymphocytes

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7 January 2021

A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma

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7 January 2021

Efficient generation of a hepatitis B virus cytotoxic T lymphocyte epitope requires the structural features of immunoproteasomes

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7 January 2021

MHC class I antigen processing of an adenovirus CTL epitope is linked to the levels of immunoproteasomes in infected cells

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7 January 2021

Modulation of proteasomal activity required for the generation of a cytotoxic T lymphocyte-defined peptide derived from the tumor antigen MAGE-3.

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7 January 2021

Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells

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7 January 2021

Thymic dendritic cells

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7 January 2021

Identification of NY-ESO-1 peptide analogues capable of improved stimulation of tumor-reactive CTL.

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7 January 2021

Dendritic Cells Infected with PoxvIn Vitro iruses Encoding MART-1/ Melan A Sensitize T Lymphocytes In Vitro

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7 January 2021

Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes

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7 January 2021

Identification of human cancers deficient in antigen processing

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7 January 2021

Antigen-processing machinery breakdown and tumor growth

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7 January 2021

Down-regulation of HLA class I antigen-processing molecules in malignant melanoma: association with disease progression

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7 January 2021

Genes encoded in the major histocompatibility complex affecting the generation of peptides for TAP transport

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7 January 2021

The major-histocompatibility-complex-encoded beta-type proteasome subunits LMP2 and LMP7. Evidence that LMP2 and LMP7 are synthesized as proproteins and that cellular levels of both mRNA and LMP-containing 20S proteasomes are differentially regulate

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7 January 2021

10.1016/S0952-7915(00)00197-7

Identifiers

DOI

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6 July 2017

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