The inositol 5-phosphatase SHIP is expressed as 145 and 135 kDa proteins in blood and bone marrow cells in vivo, whereas carboxyl-truncated forms of SHIP are generated by proteolytic cleavage in vitro. (Q32173527)

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English	The inositol 5-phosphatase SHIP is expressed as 145 and 135 kDa proteins in blood and bone marrow cells in vivo, whereas carboxyl-truncated forms of SHIP are generated by proteolytic cleavage in vitro.	scientific article

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5 November 2019

The inositol 5-phosphatase SHIP is expressed as 145 and 135 kDa proteins in blood and bone marrow cells in vivo, whereas carboxyl-truncated forms of SHIP are generated by proteolytic cleavage in vitro (English)

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5 November 2019

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5 November 2019

Christian Schulze

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5 November 2019

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S Horn

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5 November 2019

J Meyer

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5 November 2019

J Heukeshoven

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5 November 2019

S Li

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5 November 2019

J Frey

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5 November 2019

S Poll

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5 November 2019

C Stocking

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5 November 2019

M Jücker

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5 November 2019

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1 January 2001

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5 November 2019

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5 November 2019

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5 November 2019

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5 November 2019

112-120

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5 November 2019

Multiple Cytokines Stimulate the Binding of a Common 145-Kilodalton Protein to Shc at the Grb2 Recognition Site of Shc

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401990

7 January 2021

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The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401990

7 January 2021

based on heuristic

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Multiple forms of an inositol polyphosphate 5-phosphatase form signaling complexes with Shc and Grb2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401990

7 January 2021

based on heuristic

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p150Ship, a signal transduction molecule with inositol polyphosphate-5-phosphatase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401990

7 January 2021

based on heuristic

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Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401990

7 January 2021

based on heuristic

inferred from DOI database lookup

SHIP is a negative regulator of growth factor receptor-mediated PKB/Akt activation and myeloid cell survival

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401990

7 January 2021

based on heuristic

inferred from DOI database lookup

Shc interaction with Src homology 2 domain containing inositol phosphatase (SHIP) in vivo requires the Shc-phosphotyrosine binding domain and two specific phosphotyrosines on SHIP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2401990

7 January 2021

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Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin

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7 January 2021

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Effect of src infection on long-term marrow cultures: Increased self-renewal of hemopoietic progenitor cells without leukemia

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7 January 2021

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Self-renewal and differentiation of interleukin-3-dependent multipotent stem cells are modulated by stromal cells and serum factors

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7 January 2021

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Growth of factor-dependent hemopoietic precursor cell lines

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Release of spleen focus-forming virus (SFFV) from differentiation inducible promyelocytic leukemia cell lines transformed in vitro by Friend leukemia virus

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Selective immunoaffinity-based enrichment of CD34+ cells transduced with retroviral vectors containing an intracytoplasmatically truncated version of the human low-affinity nerve growth factor receptor (deltaLNGFR) gene

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Functional specificity of cytoplasmic and transmembrane tyrosine kinases: identification of 130- and 75-kilodalton substrates of c-fps/fes tyrosine kinase in macrophages

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Identification of a new adapter protein that may link the common beta subunit of the receptor for granulocyte/macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 to phosphatidylinositol 3-kinase.

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Rat insulin-degrading enzyme: cleavage pattern of the natriuretic peptide hormones ANP, BNP, and CNP revealed by HPLC and mass spectrometry

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Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor beta chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesis

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A new protein containing an SH2 domain that inhibits JAK kinases

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Role of the inositol phosphatase SHIP in negative regulation of the immune system by the receptor Fc(gamma)RIIB.

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Identifiers

10.1038/SJ.LEU.2401990

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5 November 2019

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Europe PubMed Central

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5 November 2019

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