The nonimmunosuppressive cyclosporin analogs NIM811 and UNIL025 display nanomolar potencies on permeability transition in brain-derived mitochondria. (Q33206957)

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English	The nonimmunosuppressive cyclosporin analogs NIM811 and UNIL025 display nanomolar potencies on permeability transition in brain-derived mitochondria.	scientific article

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1 January 2020

The nonimmunosuppressive cyclosporin analogs NIM811 and UNIL025 display nanomolar potencies on permeability transition in brain-derived mitochondria (English)

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1 January 2020

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Magnus J Hansson

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1 January 2020

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1 January 2020

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1 January 2020

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Marcus F Keep

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1 January 2020

Roland Månsson

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Roland Månsson

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1 January 2020

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Gustav Mattiasson

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1 January 2020

Jenny Karlsson

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1 January 2020

Peter Waldmeier

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1 January 2020

Jean-Maurice Dumont

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1 January 2020

Kamel Besseghir

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1 January 2020

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1 August 2004

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1 January 2020

Journal of Bioenergetics and Biomembranes

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1 January 2020

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1 January 2020

4

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1 January 2020

407-413

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1 January 2020

Permeability of the blood-brain barrier to the immunosuppressive cyclic peptide cyclosporin A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

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Intrathecal cyclosporin prolongs survival of late-stage ALS mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

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Dose-response of cyclosporin A in attenuating traumatic axonal injury in rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

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Regulation of the permeability transition pore, a voltage-dependent mitochondrial channel inhibited by cyclosporin A

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-derived respiring mitochondria exhibit homogeneous, complete and cyclosporin-sensitive permeability transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

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Mitochondrial permeability transition in acute neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

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Flow cytometric analysis of mitochondria from CA1 and CA3 regions of rat hippocampus reveals differences in permeability transition pore activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

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The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

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Differences in the activation of the mitochondrial permeability transition among brain regions in the rat correlate with selective vulnerability

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Powerful cyclosporin inhibition of calcium-induced permeability transition in brain mitochondria

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclophilin D as a drug target

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

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Dose-response curve and optimal dosing regimen of cyclosporin A after traumatic brain injury in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

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Cyclosporin A dramatically ameliorates CA1 hippocampal damage following transient forebrain ischaemia in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

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Restricted transport of cyclosporin A across the blood-brain barrier by a multidrug transporter, P-glycoprotein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

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Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus (HIV) type 1: interference with HIV protein-cyclophilin A interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

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In vivo pharmacological effects of ciclosporin and some analogues

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

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Inhibition of human immunodeficiency virus type 1 replication by SDZ NIM 811, a nonimmunosuppressive cyclosporine analog

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrial permeability transition pore and its role in cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocyte mitochondrial mechanisms of ischemic brain injury and neuroprotection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the mitochondrial permeability transition by the nonimmunosuppressive cyclosporin derivative NIM811.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mitochondrion in apoptosis: how Pandora's box opens

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, and cyclosporin A-sensitive channel.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The permeability transition pore complex: another view.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

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Rapid isolation of metabolically active mitochondria from rat brain and subregions using Percoll density gradient centrifugation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15377880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/B:JOBB.0000041776.31885.45

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15377880%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

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1 January 2020

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