Platelet PECAM-1 inhibits thrombus formation in vivo. (Q33223436)

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6 January 2020

title

Platelet PECAM-1 inhibits thrombus formation in vivo (English)

1 reference

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6 January 2020

author name string

Shahrokh Falati

1

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6 January 2020

Sonali Patil

2

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6 January 2020

Peter L Gross

3

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6 January 2020

Michelle Stapleton

4

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6 January 2020

Glenn Merrill-Skoloff

5

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6 January 2020

Katherine L Pixton

7

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6 January 2020

Harmut Weiler

8

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6 January 2020

Brian Cooley

9

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6 January 2020

Peter J Newman

11

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6 January 2020

Barbara C Furie

12

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6 January 2020

Bruce Furie

13

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6 January 2020

Jonathan M Gibbins

14

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6 January 2020

language of work or name

English

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publication date

15 September 2005

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6 January 2020

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6 January 2020

volume

107

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6 January 2020

issue

2

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6 January 2020

page(s)

535-541

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Initial accumulation of platelets during arterial thrombus formation in vivo is inhibited by elevation of basal cAMP levels

6 January 2020

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Physical proximity and functional interplay of PECAM-1 with the Fc receptor Fc gamma RIIa on the platelet plasma membrane

14 July 2018

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Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin

14 July 2018

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PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis

14 July 2018

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Apoptosis disables CD31-mediated cell detachment from phagocytes promoting binding and engulfment

14 July 2018

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Glycoprotein IIb-IIIa-dependent aggregation by glycoprotein Ibalpha is reinforced by a Src family kinase inhibitor (PP1)-sensitive signalling pathway

14 July 2018

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Laser-induced noninvasive vascular injury models in mice generate platelet- and coagulation-dependent thrombi

14 July 2018

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Platelet endothelial cell adhesion molecule-1 serves as an inhibitory receptor that modulates platelet responses to collagen

14 July 2018

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Integrin activation by regulated dimerization and oligomerization of platelet endothelial cell adhesion molecule (PECAM)-1 from within the cell

14 July 2018

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PECAM-1 (CD31) expression modulates bleeding time in vivo

14 July 2018

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The small GTPase, Rap1, mediates CD31-induced integrin adhesion

14 July 2018

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A new role for platelet-endothelial cell adhesion molecule-1 (CD31): inhibition of TCR-mediated signal transduction

14 July 2018

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Genetic evidence for functional redundancy of Platelet/Endothelial cell adhesion molecule-1 (PECAM-1): CD31-deficient mice reveal PECAM-1-dependent and PECAM-1-independent functions.

14 July 2018

1 reference

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Recruitment and activation of SHP-1 protein-tyrosine phosphatase by human platelet endothelial cell adhesion molecule-1 (PECAM-1). Identification of immunoreceptor tyrosine-based inhibitory motif-like binding motifs and substrates

14 July 2018

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Human CD38 (ADP-ribosyl cyclase) is a counter-receptor of CD31, an Ig superfamily member

14 July 2018

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Engagement of human PECAM-1 (CD31) on human endothelial cells increases intracellular calcium ion concentration and stimulates prostacyclin release

14 July 2018

1 reference

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Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of platelet/endothelial cell adhesion molecule-1 (PECAM-1) that are required for the cellular association and activation of the protein-tyrosine phosphatase, SHP-2

14 July 2018

1 reference

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Glycoprotein VI is the collagen receptor in platelets which underlies tyrosine phosphorylation of the Fc receptor gamma-chain

14 July 2018

1 reference

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Residues on both faces of the first immunoglobulin fold contribute to homophilic binding sites of PECAM-1/CD31

14 July 2018

1 reference

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The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen

14 July 2018

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A novel phosphotyrosine motif with a critical amino acid at position -2 for the SH2 domain-mediated activation of the tyrosine phosphatase SHP-1

14 July 2018

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14 July 2018

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Identification of alpha v beta 3 as a heterotypic ligand for CD31/PECAM-1

14 July 2018

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Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression

14 July 2018

1 reference

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Individually distinct Ig homology domains in PECAM-1 regulate homophilic binding and modulate receptor affinity

14 July 2018

1 reference

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Role of platelet-endothelial cell adhesion molecule (PECAM) in platelet adhesion/aggregation over injured but not denuded endothelium in vivo and ex vivo

14 July 2018

1 reference

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Roles of platelet/endothelial cell adhesion molecule-1 (PECAM-1, CD31) in natural killer cell transendothelial migration and beta 2 integrin activation.

14 July 2018

1 reference

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Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system.

14 July 2018

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Murine platelet endothelial cell adhesion molecule (PECAM-1)/CD31 modulates beta 2 integrins on lymphokine-activated killer cells

14 July 2018

1 reference

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PECAM-1 is required for transendothelial migration of leukocytes

14 July 2018

1 reference

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Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivo

14 July 2018

1 reference

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Anti-CD31 delays platelet adhesion/aggregation at sites of endothelial injury in mouse cerebral arterioles

14 July 2018

1 reference

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Ligation of platelet/endothelial cell adhesion molecule 1 (PECAM-1/CD31) on monocytes and neutrophils increases binding capacity of leukocyte CR3 (CD11b/CD18).

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895610

Signals from platelet/endothelial cell adhesion molecule enhance the adhesive activity of the very late antigen-4 integrin of human CD34+ hemopoietic progenitor cells.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895610

Syk interacts with tyrosine-phosphorylated proteins in human platelets activated by collagen and cross-linking of the Fc gamma-IIA receptor

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895610

A human endothelial cell-restricted, externally disposed plasmalemmal protein enriched in intercellular junctions

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895610

Rat model of arterial thrombosis induced by ferric chloride

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895610

Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895610

PECAM-1 (CD31) Cloning and Relation to Adhesion Molecules of the Immunoglobulin Gene Superfamily

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895610

CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895610

Murine thrombosis models.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895610

PECAM-1 negatively regulates GPIb/V/IX signaling in murine platelets

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895610

Platelet endothelial cell adhesion molecule-1 signaling inhibits the activation of human platelets

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895610

Platelet endothelial cell adhesion molecule-1 is a negative regulator of platelet-collagen interactions

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895610

Inhibition of antigen-receptor signaling by Platelet Endothelial Cell Adhesion Molecule-1 (CD31) requires functional ITIMs, SHP-2, and p56(lck).

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895610

Collagen, convulxin, and thrombin stimulate aggregation-independent tyrosine phosphorylation of CD31 in platelets. Evidence for the involvement of Src family kinases

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895610

Platelet/endothelial cell adhesion molecule-1 serves as a costimulatory agonist receptor that modulates integrin-dependent adhesion and aggregation of human platelets.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1895610

Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) acts as a regulator of B-cell development, B-cell antigen receptor (BCR)-mediated activation, and autoimmune disease

31 October 2018

1 reference

12 December 2020

Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse

1 reference

12 December 2020

Ligation of CD31 (PECAM-1) on endothelial cells increases adhesive function of alphavbeta3 integrin and enhances beta1 integrin-mediated adhesion of eosinophils to endothelial cells

1 reference

12 December 2020

Glycoprotein Ib-V-IX, a receptor for von Willebrand factor, couples physically and functionally to the Fc receptor gamma-chain, Fyn, and Lyn to activate human platelets

1 reference

12 December 2020

Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation

1 reference

12 December 2020

Endothelial cell PECAM-1 confers protection against endotoxic shock

1 reference

12 December 2020

Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall

1 reference

12 December 2020

Lack of in vivo function of CD31 in vascular thrombosis

1 reference

12 December 2020

A novel leukocyte differentiation antigen: two monoclonal antibodies TM2 and TM3 define a 120-kd molecule present on neutrophils, monocytes, platelets, and activated lymphoblasts

1 reference

12 December 2020

Tyrosine Phosphorylation of the Fc Receptor γ-Chain in Collagen-stimulated Platelets

1 reference

12 December 2020

Regulation of arterial thrombolysis by plasminogen activator inhibitor-1 in mice

1 reference

12 December 2020

Assessment of thrombin inhibitor efficacy in a novel rabbit model of simultaneous arterial and venous thrombosis

1 reference

12 December 2020

10.1182/BLOOD-2005-04-1512

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16166583%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16166583%20AND%20SRC:MED&resulttype=core&format=json

6 January 2020

PubMed publication ID

16166583

1 reference