Diversity-oriented synthesis: exploring the intersections between chemistry and biology (Q33231454)

24 July 2017

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title

Diversity-oriented synthesis: exploring the intersections between chemistry and biology (English)

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24 July 2017

Derek S Tan

1

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24 July 2017

publication date

1 July 2005

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24 July 2017

published in

Nature Chemical Biology

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24 July 2017

volume

1

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24 July 2017

issue

2

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24 July 2017

page(s)

74-84

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Discovery and applications of small molecule probes for studying biological processes

24 July 2017

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Chemical genomic profiling of biological networks using graph theory and combinations of small molecule perturbations

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Multidimensional chemical genetic analysis of diversity-oriented synthesis-derived deacetylase inhibitors using cell-based assays

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Diversity-oriented synthesis of azaspirocycles

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Discovery of an inhibitor of a transcription factor using small molecule microarrays and diversity-oriented synthesis

21 January 2018

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21 January 2018

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21 January 2018

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Understanding the effects of the polymer support on reaction rates and kinetics: knowledge toward efficient synthetic design

21 January 2018

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Solutions for library encoding to create collections of discrete compounds

21 January 2018

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Fast Calculation of Molecular Polar Surface Area as a Sum of Fragment-Based Contributions and Its Application to the Prediction of Drug Transport Properties

21 January 2018

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Chemical space and biology

21 January 2018

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7 January 2021

Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists

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Design of compound libraries based on natural product scaffolds and protein structure similarity clustering (PSSC).

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7 January 2021

Current progress in natural product-like libraries for discovery screening

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https://api.crossref.org/works/10.1038%2FNCHEMBIO0705-74

7 January 2021

Cell-based partitioning

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7 January 2021

Relationship of stereochemical and skeletal diversity of small molecules to cellular measurement space

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7 January 2021

Dimethylzinc-mediated additions of alkenylzirconocenes to aldimines. New methodologies for allylic amine and C-cyclopropylalkylamine syntheses

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7 January 2021

A homo [3+2] dipolar cycloaddition: the reaction of nitrones with cyclopropanes

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7 January 2021

Three-component homo 3 + 2 dipolar cycloaddition. A diversity-oriented synthesis of tetrahydro-1,2-oxazines and FR900482 skeletal congeners

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7 January 2021

https://api.crossref.org/works/10.1038%2FNCHEMBIO0705-74

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7 January 2021

A three-component reaction for diversity-oriented synthesis of polysubstituted piperidines: solution and solid-phase optimization of the first tandem aza[4+2]/allylboration

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https://api.crossref.org/works/10.1038%2FNCHEMBIO0705-74

7 January 2021

Skeletal diversity via a folding pathway: synthesis of indole alkaloid-like skeletons

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https://api.crossref.org/works/10.1038%2FNCHEMBIO0705-74

7 January 2021

Small molecules that induce cardiomyogenesis in embryonic stem cells

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https://api.crossref.org/works/10.1038%2FNCHEMBIO0705-74

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Profile. K. C. Nicolaou

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7 January 2021

Identifiers

DOI

10.1038/NCHEMBIO0705-74

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24 July 2017

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