The oxidative stress metabolite 4-hydroxynonenal promotes Alzheimer protofibril formation (Q33272109)

25 July 2017

title

The oxidative stress metabolite 4-hydroxynonenal promotes Alzheimer protofibril formation (English)

1 reference

25 July 2017

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Evan T Powers

3

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Jeffery W. Kelly

series ordinal

4

object named as

Jeffery W Kelly

1 reference

25 July 2017

Sarah J Siegel

1

1 reference

25 July 2017

Jan Bieschke

series ordinal

2

1 reference

25 July 2017

language of work or name

English

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publication date

1 February 2007

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25 July 2017

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25 July 2017

volume

46

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25 July 2017

issue

6

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25 July 2017

page(s)

1503-1510

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Opposing activities protect against age-onset proteotoxicity

25 July 2017

cites work

1 reference

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Mass spectrometry for detection of 4-hydroxy-trans-2-nonenal (HNE) adducts with peptides and proteins.

21 June 2018

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Metabolite-initiated protein misfolding may trigger Alzheimer's disease

21 June 2018

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Evidence for Ozone Formation in Human Atherosclerotic Arteries

21 June 2018

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4-hydroxynonenal and neurodegenerative diseases

21 June 2018

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4-hydroxynonenal from pathology to physiology

21 June 2018

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Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

21 June 2018

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Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review

21 June 2018

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21 June 2018

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 June 2018

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21 June 2018

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Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

21 June 2018

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Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

21 June 2018

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Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

21 June 2018

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Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

21 June 2018

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21 June 2018

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Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

21 June 2018

1 reference

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Modification of histidine residues in proteins by reaction with 4-hydroxynonenal

21 June 2018

1 reference

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Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

21 June 2018

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Covalent adduction of human serum albumin by 4-hydroxy-2-nonenal: kinetic analysis of competing alkylation reactions.

21 June 2018

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Prefibrillar amyloid aggregates could be generic toxins in higher organisms.

31 October 2018

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Oxidative metabolites accelerate Alzheimer's amyloidogenesis by a two-step mechanism, eliminating the requirement for nucleation

31 October 2018

1 reference

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Characterisation of adducts of the lipid peroxidation product 4-hydroxy-2-nonenal and amyloid beta-peptides by liquid chromatography/electrospray ionisation mass spectrometry

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2530822

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

31 October 2018

1 reference

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Increased oxidative stress in Alzheimer's disease as assessed with 4-hydroxynonenal but not malondialdehyde

31 October 2018

1 reference

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4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release.

31 October 2018

1 reference

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Amyloid beta protein 1-40 and 1-42 levels in matched cerebrospinal fluid and plasma from patients with Alzheimer disease

31 October 2018

1 reference

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Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2530822

Histochemical detection of 4-hydroxynonenal protein in Alzheimer amyloid

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2530822

Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2530822

Clinicopathologic studies in cognitively healthy aging and Alzheimer's disease: relation of histologic markers to dementia severity, age, sex, and apolipoprotein E genotype

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2530822

Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2530822

4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2530822

Structural definition of early lysine and histidine adduction chemistry of 4-hydroxynonenal

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17279615

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/BI061853S

1 reference

25 July 2017

1 reference

25 July 2017

1 reference