The trypanosome transcriptome is remodelled during differentiation but displays limited responsiveness within life stages (Q33345915)

26 July 2017

title

The trypanosome transcriptome is remodelled during differentiation but displays limited responsiveness within life stages (English)

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glycosylphosphatidylinositol-specific phospholipase C

26 July 2017

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5 February 2019

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5 February 2019

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UDP-glucose pyrophosphorylase

5 February 2019

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5 February 2019

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6 February 2019

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6 February 2019

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6 February 2019

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UTP-glucose-1-phosphate uridylyltransferase

6 February 2019

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6 February 2019

heat shock protein 70

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6 February 2019

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glycosylphosphatidylinositol-specific phospholipase C

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UTP-glucose-1-phosphate uridylyltransferase 2, putative

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UTP-glucose-1-phosphate uridylyltransferase 2, putative

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UDP-glucose pyrophosphorylase

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UDP-glucose pyrophosphorylase

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Mark C Field

4

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Senthil Kumar A Natesan

series ordinal

2

object named as

Senthil Kumar A Natesan

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26 July 2017

V Lila Koumandou

1

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26 July 2017

Tatiana Sergeenko

series ordinal

3

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26 July 2017

language of work or name

English

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publication date

23 June 2008

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26 July 2017

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26 July 2017

volume

9

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26 July 2017

page(s)

298

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describes a project that uses

26 July 2017

limma

object named as

limma

2 references

22 June 2022

https://europepmc.org/article/PMC/2443814

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

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21 June 2018

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Common features and interesting differences in transcriptional responses to secretion stress in the fungi Trichoderma reesei and Saccharomyces cerevisiae

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21 June 2018

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Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi

21 June 2018

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21 June 2018

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21 June 2018

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The Genome of the African Trypanosome Trypanosoma brucei

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Variant surface glycoprotein RNA interference triggers a precytokinesis cell cycle arrest in African trypanosomes

21 June 2018

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21 June 2018

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A bioinformatic analysis of the RAB genes of Trypanosoma brucei

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Characterization of two protein disulfide isomerases from the endocytic pathway of bloodstream forms of Trypanosoma brucei

21 June 2018

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Trypanosomatid flagellum biogenesis: ARL-3A is involved in several species.

21 June 2018

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Cold shock and regulation of surface protein trafficking convey sensitization to inducers of stage differentiation in Trypanosoma brucei

21 June 2018

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Intracellular membrane transport systems in Trypanosoma brucei

21 June 2018

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Both of the Rab5 subfamily small GTPases of Trypanosoma brucei are essential and required for endocytosis.

21 June 2018

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21 June 2018

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TbRAB1 and TbRAB2 mediate trafficking through the early secretory pathway of Trypanosoma brucei

21 June 2018

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Axenic culture of African trypanosome bloodstream forms

21 June 2018

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Comparative genomics of transcriptional control in the human malaria parasite Plasmodium falciparum

21 June 2018

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Clathrin adaptor epsinR is required for retrograde sorting on early endosomal membranes

21 June 2018

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21 June 2018

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21 June 2018

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Clathrin-mediated endocytosis is essential in Trypanosoma brucei.

21 June 2018

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21 June 2018

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21 June 2018

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OligoArray 2.0: design of oligonucleotide probes for DNA microarrays using a thermodynamic approach

21 June 2018

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RNA polymerase I transcribes procyclin genes and variant surface glycoprotein gene expression sites in Trypanosoma brucei

21 June 2018

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Expression profiling reveals off-target gene regulation by RNAi

21 June 2018

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Rab5 and Rab11 mediate transferrin and anti-variant surface glycoprotein antibody recycling in Trypanosoma brucei

21 June 2018

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Clan CD cysteine peptidases of parasitic protozoa

21 June 2018

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RhoD, Src, and hDia2C in endosome motility

21 June 2018

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Identifying differentially expressed genes using false discovery rate controlling procedures

21 June 2018

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Receptor downregulation and multivesicular-body sorting

21 June 2018

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Stage-specific requirement of a mitogen-activated protein kinase by Trypanosoma brucei

21 June 2018

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Regulating the actin cytoskeleton during vesicular transport.

21 June 2018

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Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae

21 June 2018

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Life without transcriptional control? From fly to man and back again

21 June 2018

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21 June 2018

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Differential endocytic functions of Trypanosoma brucei Rab5 isoforms reveal a glycosylphosphatidylinositol-specific endosomal pathway.

21 June 2018

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Active site mapping, biochemical properties and subcellular localization of rhodesain, the major cysteine protease of Trypanosoma brucei rhodesiense

21 June 2018

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A developmentally regulated rab11 homologue in Trypanosoma brucei is involved in recycling processes

21 June 2018

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Developmental and morphological regulation of clathrin-mediated endocytosis in Trypanosoma brucei.

21 June 2018

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Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals

21 June 2018

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Rab proteins as membrane organizers

21 June 2018

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Aspects of gene regulation during the UPR in human cells

21 June 2018

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Functional discovery via a compendium of expression profiles

21 June 2018

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Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

21 June 2018

1 reference

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Characterization of a novel alanine-rich protein located in surface microdomains in Trypanosoma brucei

21 June 2018

1 reference

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Pathways involved in environmental sensing in trypanosomatids.

21 June 2018

1 reference

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Cyclic AMP signaling in trypanosomatids

21 June 2018

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Iron-dependent regulation of transferrin receptor expression in Trypanosoma brucei.

21 June 2018

1 reference

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Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13

21 June 2018

1 reference

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Modular PH and C2 domains in membrane attachment and other functions

21 June 2018

1 reference

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The Ca-calmodulin-dependent protein kinase cascade

21 June 2018

1 reference

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A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei

21 June 2018

1 reference

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The Rab5 effector EEA1 is a core component of endosome docking

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Cluster analysis and display of genome-wide expression patterns

21 June 2018

1 reference

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Both IgM and IgG anti-VSG antibodies initiate a cycle of aggregation-disaggregation of bloodstream forms of Trypanosoma brucei without damage to the parasite

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Tlg2p, a yeast syntaxin homolog that resides on the Golgi and endocytic structures

21 June 2018

1 reference

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Association of nucleoside diphosphate kinase nm23-H2 with human telomeres

21 June 2018

1 reference

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Exploring the metabolic and genetic control of gene expression on a genomic scale

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

The bloodstream differentiation-division of Trypanosoma brucei studied using mitochondrial markers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Characterization of the Trypanosoma brucei homologue of a Trypanosoma cruzi flagellum-adhesion glycoprotein.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Mutational analysis of NM23-H2/NDP kinase identifies the structural domains critical to recognition of a c-myc regulatory element

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

A role for a 70-kilodalton heat shock protein in lysosomal degradation of intracellular proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

A developmentally regulated gene of trypanosomes encodes a homologue of rat protein-disulfide isomerase and phosphoinositol-phospholipase C.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Protein folding in the cell

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Transcription of the heat shock 70 locus in Trypanosoma brucei

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Characterization of a cDNA encoding a cysteine-rich cell surface protein located in the flagellar pocket of the protozoan Trypanosoma brucei

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Molecular characterization of two invariant surface glycoproteins specific for the bloodstream stage of Trypanosoma brucei

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Capping of variable antigen on Trypanosoma brucei, and its immunological and biological significance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Cultivation and in vitro cloning or procyclic culture forms of Trypanosoma brucei in a semi-defined medium. Short communication

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Ubiquitylation is required for degradation of transmembrane surface proteins in trypanosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Evolution of the multivesicular body ESCRT machinery; retention across the eukaryotic lineage

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

How complex is GTPase signaling in trypanosomes?

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Control and regulation of gene expression: quantitative analysis of the expression of phosphoglycerate kinase in bloodstream form Trypanosoma brucei

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

WCB is a C2 domain protein defining the plasma membrane - sub-pellicular microtubule corset of kinetoplastid parasites.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Asymmetric cell division as a route to reduction in cell length and change in cell morphology in trypanosomes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Dileucine signal-dependent and AP-1-independent targeting of a lysosomal glycoprotein in Trypanosoma brucei

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

A family of stage-specific alanine-rich proteins on the surface of epimastigote forms of Trypanosoma brucei.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Bloodstream form Trypanosoma brucei depend upon multiple metacaspases associated with RAB11-positive endosomes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Tropolysin, a new oligopeptidase from African trypanosomes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

PERK (eIF2alpha kinase) is required to activate the stress-activated MAPKs and induce the expression of immediate-early genes upon disruption of ER calcium homoeostasis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

The transcriptomes of Trypanosoma brucei Lister 427 and TREU927 bloodstream and procyclic trypomastigotes.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Systematic analysis of SNARE molecules in Arabidopsis: dissection of the post-Golgi network in plant cells.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Cytoplasmic targeting signals in transmembrane invariant surface glycoproteins of trypanosomes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Syntaxin 4 transgenic mice exhibit enhanced insulin-mediated glucose uptake in skeletal muscle

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Nucleoside diphosphate kinase of Mycobacterium tuberculosis acts as GTPase-activating protein for Rho-GTPases

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Factors affecting the level and localization of the transferrin receptor in Trypanosoma brucei.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

The Expression of the t-SNARE AtSNAP33 Is Induced by Pathogens and Mechanical Stimulation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Expression and Function of the Trypanosoma brucei Major Surface Protease (GP63) Genes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Genomic analysis of the unfolded protein response in Arabidopsis shows its connection to important cellular processes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

31 October 2018

Biological revelations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Arginine kinase: a common feature for management of energy reserves in African and American flagellated trypanosomatids

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Multiple procyclin isoforms are expressed differentially during the development of insect forms of Trypanosoma brucei.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Isolation and characterization of subnuclear compartments from Trypanosoma brucei. Identification of a major repetitive nuclear lamina component.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Reversible interruption of Giardia lamblia cyst wall protein transport in a novel regulated secretory pathway

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Cloning, heterologous expression and kinetic analysis of glycerol kinase (TbGLK1) from Trypanosoma brucei.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Nucleoside diphosphate kinase of Trypanosoma brucei

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Points of convergence between Ca2+ and Ras signalling pathways.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Families of adenylate cyclase genes in Trypanosoma brucei

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Molecular characterization of the mitochondrial heat shock protein 60 gene from Trypanosoma brucei

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Alteration of pyruvate metabolism in African trypanosomes during differentiation from bloodstream into insect forms

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Biosynthesis of Trypanosoma brucei variant surface glycoproteins. N-glycosylation and addition of a phosphatidylinositol membrane anchor.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Hydrodynamic Flow-Mediated Protein Sorting on the Cell Surface of Trypanosomes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2443814

A mitogen-activated protein kinase of Trypanosoma brucei confers resistance to temperature stress

31 October 2018

1 reference

12 December 2020

Trypanosoma brucei FLA1 is required for flagellum attachment and cytokinesis

1 reference

12 December 2020

Distinct roles for the cytoplasmic tail sequences of Emp24p and Erv25p in transport between the endoplasmic reticulum and Golgi complex

1 reference

12 December 2020

A comparison of the glycosomes (microbodies) isolated from Trypanosoma brucei bloodstream form and cultured procyclic trypomastigotes

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2164-9-298

1 reference

Dimensions Publication ID

26 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2164-9-298

9 September 2019

1 reference

26 July 2017

1 reference