Modeling how CD46 deficiency predisposes to atypical hemolytic uremic syndrome (Q33372897)

26 July 2017

title

Modeling how CD46 deficiency predisposes to atypical hemolytic uremic syndrome (English)

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atypical hemolytic uremic syndrome

26 July 2017

main subject

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4

Timothy H J Goodship

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26 July 2017

1

M Kathryn Liszewski

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26 July 2017

5

John P Atkinson

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26 July 2017

Marilyn K Leung

2

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26 July 2017

Barbara Schraml

series ordinal

3

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26 July 2017

publication date

5 October 2006

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26 July 2017

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26 July 2017

volume

44

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26 July 2017

issue

7

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26 July 2017

page(s)

1559-1568

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Implications of the initial mutations in membrane cofactor protein (MCP; CD46) leading to atypical hemolytic uremic syndrome

26 July 2017

cites work

1 reference

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Genetic and functional analyses of membrane cofactor protein (CD46) mutations in atypical hemolytic uremic syndrome

21 June 2018

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Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome

21 June 2018

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The central role of the alternative complement pathway in human disease

21 June 2018

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Hemolytic uremic syndrome: an example of insufficient complement regulation on self-tissue

21 June 2018

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Insights into hemolytic uremic syndrome: segregation of three independent predisposition factors in a large, multiple affected pedigree

21 June 2018

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Emerging roles and new functions of CD46

21 June 2018

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Atypical haemolytic uraemic syndrome and mutations in complement regulator genes

21 June 2018

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Complement and diseases: defective alternative pathway control results in kidney and eye diseases

21 June 2018

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Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome

21 June 2018

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A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration

21 June 2018

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The development of atypical haemolytic-uraemic syndrome is influenced by susceptibility factors in factor H and membrane cofactor protein: evidence from two independent cohorts

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32.

21 June 2018

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Anti-Factor H autoantibodies associated with atypical hemolytic uremic syndrome

21 June 2018

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Complement factor I: a susceptibility gene for atypical haemolytic uraemic syndrome

21 June 2018

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Non-enteropathic hemolytic uremic syndrome: causes and short-term course.

21 June 2018

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Mutations in CD46, a complement regulatory protein, predispose to atypical HUS.

21 June 2018

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Clinico-pathological findings in diarrhoea-negative haemolytic uraemic syndrome

21 June 2018

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21 June 2018

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Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome

21 June 2018

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Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndrome

21 June 2018

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21 June 2018

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Role of membrane cofactor protein (CD46) in regulation of C4b and C3b deposited on cells

21 June 2018

1 reference

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Factor H mutations in hemolytic uremic syndrome cluster in exons 18-20, a domain important for host cell recognition

21 June 2018

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Clustering of missense mutations in the C-terminal region of factor H in atypical hemolytic uremic syndrome.

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Adult Hemolytic Uremic Syndrome with Renal Arteriolar Deposition of IgM and C3

21 June 2018

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Hemolytic Uremic Syndrome

21 June 2018

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Effects of complement factor D deficiency on the renal disease of MRL/lpr mice

31 October 2018

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Thrombotic Microangiopathies

31 October 2018

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Structure and composition of drusen associated with glomerulonephritis: implications for the role of complement activation in drusen biogenesis.

31 October 2018

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Dissecting Sites Important for Complement Regulatory Activity in Membrane Cofactor Protein (MCP; CD46)

31 October 2018

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A human cell-surface antigen defined by a monoclonal antibody and controlled by a gene on human chromosome 1

10 December 2018

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12 December 2020

Membrane cofactor protein (CD46) protects cells predominantly from alternative complement pathway-mediated C3-fragment deposition and cytolysis

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12 December 2020

Membrane cofactor protein (MCP; CD46). Isoforms differ in protection against the classical pathway of complement

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12 December 2020

Control of C3b and C5b deposition by CD46 (membrane cofactor protein) after alternative but not classical complement activation

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12 December 2020

Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B

1 reference

12 December 2020

10.1016/J.MOLIMM.2006.08.024

Identifiers

DOI

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26 July 2017

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26 July 2017

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