The role of CTLA-4 in the regulation of T cell immune responses. (Q33547785)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10101680%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

review article

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title

The role of CTLA-4 in the regulation of T cell immune responses (English)

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12 November 2019

2

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12 November 2019

author name string

K D McCoy

series ordinal

1

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12 November 2019

publication date

1 February 1999

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10101680%20AND%20SRC:MED&resulttype=core&format=json

Immunology & Cell Biology

12 November 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10101680%20AND%20SRC:MED&resulttype=core&format=json

12 November 2019

volume

77

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12 November 2019

issue

1

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12 November 2019

page(s)

1-10

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A Theory of Self-Nonself Discrimination: Paralysis and induction involve the recognition of one and two determinants on an antigen, respectively

12 November 2019

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The role of the CD28 receptor during T cell responses to antigen

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Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation

21 January 2018

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A new member of the immunoglobulin superfamily--CTLA-4

21 January 2018

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Cd28 and Ctla-4, two related members of the Ig supergene family, are tightly linked on proximal mouse chromosome 1

21 January 2018

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Human CD28 and CTLA-4 Ig superfamily genes are located on chromosome 2 at bands q33-q34.

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Rescue of thymocytes from glucocorticoid-induced cell death mediated by CD28/CTLA-4 costimulatory interactions with B7-1/B7-2

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Coexpression and functional cooperation of CTLA-4 and CD28 on activated T lymphocytes

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CTLA-4 can function as a negative regulator of T cell activation

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Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains

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CTLA-4 is a second receptor for the B cell activation antigen B7

21 January 2018

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Uncovering of Functional Alternative CTLA-4 Counter-Receptor in B7-Deficient Mice

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B70 antigen is a second ligand for CTLA-4 and CD28

21 January 2018

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Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1.

21 January 2018

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CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

21 January 2018

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Distinct roles for CD28 and cytotoxic T lymphocyte-associated molecule-4 receptors during T cell activation?

21 January 2018

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CTLA-4-B7 interaction is sufficient to costimulate T cell clonal expansion

21 January 2018

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CTLA4 mediates antigen-specific apoptosis of human T cells

21 January 2018

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CTLA-4 ligation blocks CD28-dependent T cell activation

21 January 2018

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CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells

21 January 2018

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The Yin and Yang of T cell costimulation

21 January 2018

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Superantigen responses and co-stimulation: CD28 and CTLA-4 have opposing effects on T cell expansion in vitro and in vivo

21 January 2018

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Enhancement of antitumor immunity by CTLA-4 blockade

21 January 2018

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Protective immunity to nematode infection is induced by CTLA-4 blockade

21 January 2018

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Cytotoxic T lymphocyte antigen 4 (CTLA4) blockade accelerates the acute rejection of cardiac allografts in CD28-deficient mice: CTLA4 can function independently of CD28.

21 January 2018

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B7-1 engagement of cytotoxic T lymphocyte antigen 4 inhibits T cell activation in the absence of CD28.

21 January 2018

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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

21 January 2018

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Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

21 January 2018

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Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells

21 January 2018

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Apoptosis in the pathogenesis and treatment of disease

21 January 2018

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Normal thymic selection, normal viability and decreased lymphoproliferation in T cell receptor-transgenic CTLA-4-deficient mice

21 January 2018

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Thymocyte development is normal in CTLA-4-deficient mice

21 January 2018

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CTLA-4, a negative regulator of T-lymphocyte activation

21 January 2018

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Src family tyrosine kinases associate with and phosphorylate CTLA-4 (CD152).

21 January 2018

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21 January 2018

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21 January 2018

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Cytotoxic T lymphocyte antigen 4 (CTLA-4) interferes with extracellular signal-regulated kinase (ERK) and Jun NH2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor zeta and ZAP70.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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CTLA4 gene polymorphism confers susceptibility to Graves' disease in Japanese

21 January 2018

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A CTLA-4 gene polymorphism is associated with both Graves disease and autoimmune hypothyroidism

21 January 2018

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Induction of peripheral T cell tolerance in vivo requires CTLA-4 engagement.

21 January 2018

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Making the T cell receptor go the distance: a topological view of T cell activation

21 January 2018

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Signals and signs for lymphocyte responses

21 January 2018

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The anatomy of T-cell activation and tolerance

21 January 2018

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The role of CTLA-4 in the regulation and initiation of T-cell responses

21 January 2018

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The emerging role of CTLA-4 as an immune attenuator

21 January 2018

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Differential requirements for survival and proliferation of CD8 naïve or memory T cells

21 January 2018

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The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

21 January 2018

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Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2

21 January 2018

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