Sorafenib and HDAC inhibitors synergize with TRAIL to kill tumor cells (Q33576187)

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English	Sorafenib and HDAC inhibitors synergize with TRAIL to kill tumor cells	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

23674352

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28 July 2017

title

Sorafenib and HDAC inhibitors synergize with TRAIL to kill tumor cells (English)

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Europe PubMed Central

PubMed publication ID

23674352

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28 July 2017

author

Paul Dent

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5

object named as

Paul Dent

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Europe PubMed Central

PubMed publication ID

23674352

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28 July 2017

author name string

Hossein A Hamed

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1

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Europe PubMed Central

PubMed publication ID

23674352

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28 July 2017

Yukihiro Yamaguchi

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2

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Europe PubMed Central

PubMed publication ID

23674352

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28 July 2017

Paul B Fisher

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3

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Europe PubMed Central

PubMed publication ID

23674352

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28 July 2017

Steven Grant

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4

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Europe PubMed Central

PubMed publication ID

23674352

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28 July 2017

publication date

1 October 2013

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Europe PubMed Central

PubMed publication ID

23674352

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28 July 2017

published in

Journal of Cellular Physiology

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Europe PubMed Central

PubMed publication ID

23674352

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28 July 2017

volume

228

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Europe PubMed Central

PubMed publication ID

23674352

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28 July 2017

issue

10

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Europe PubMed Central

PubMed publication ID

23674352

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28 July 2017

page(s)

1996-2005

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Europe PubMed Central

PubMed publication ID

23674352

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28 July 2017

cites work

HDAC inhibitors synergize antiproliferative effect of sorafenib in renal cell carcinoma cells.

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PubMed Central

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21 June 2018

On the TRAIL to successful cancer therapy? Predicting and counteracting resistance against TRAIL-based therapeutics

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PubMed Central

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21 June 2018

Combination therapy for hepatocellular carcinoma: additive preclinical efficacy of the HDAC inhibitor panobinostat with sorafenib

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PubMed Central

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21 June 2018

TRAIL signaling and synergy mechanisms used in TRAIL-based combination therapies

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PubMed Central

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21 June 2018

Sorafenib enhances pemetrexed cytotoxicity through an autophagy-dependent mechanism in cancer cells

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PubMed Central

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Developing histone deacetylase inhibitors as anti-cancer therapeutics

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Platinum resistant cancer cells conserve sensitivity to BH3 domains and obatoclax induced mitochondrial apoptosis

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Inhibition of MCL-1 in breast cancer cells promotes cell death in vitro and in vivo

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21 June 2018

TRAIL receptor signaling and therapeutics.

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PubMed Central

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21 June 2018

Sorafenib Activates CD95 and Promotes Autophagy and Cell Death via Src Family Kinases in Gastrointestinal Tumor Cells

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PubMed Central

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21 June 2018

Vorinostat and sorafenib increase CD95 activation in gastrointestinal tumor cells through a Ca(2+)-de novo ceramide-PP2A-reactive oxygen species-dependent signaling pathway

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21 June 2018

Targeting mitochondria for cancer therapy

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21 June 2018

A Bax-mediated mechanism for obatoclax-induced apoptosis of cholangiocarcinoma cells

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Heat shock protein 90 - a potential target in the treatment of human acute myelogenous leukemia

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21 June 2018

Mimicking the BH3 domain to kill cancer cells

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PubMed Central

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21 June 2018

BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing

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21 June 2018

Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms

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21 June 2018

Sorafenib tosylate in advanced kidney cancer: past, present and future

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21 June 2018

Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling

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21 June 2018

Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation

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PubMed Central

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21 June 2018

Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization.

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PubMed Central

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21 June 2018

Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death.

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CD95 tyrosine phosphorylation is required for CD95 oligomerization

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Involvement of NADPH oxidase isoforms and Src family kinases in CD95-dependent hepatocyte apoptosis

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Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

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Fluorescence resonance energy transfer analysis of proapoptotic CD95-EGF receptor interactions in Huh7 cells.

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The multikinase inhibitor Sorafenib induces apoptosis and sensitises endometrial cancer cells to TRAIL by different mechanisms.

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Involvement of the Src family kinase yes in bile salt-induced apoptosis

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Cleavage of CD95 by matrix metalloproteinase-7 induces apoptosis resistance in tumour cells

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Identifiers

DOI

10.1002/JCP.24362

1 reference

stated in

Europe PubMed Central

PubMed publication ID

23674352

retrieved

28 July 2017

PMC publication ID

4012564

1 reference

stated in

Europe PubMed Central

PubMed publication ID

23674352

retrieved

28 July 2017

PubMed publication ID

23674352

1 reference

stated in

Europe PubMed Central

PubMed publication ID

23674352

retrieved

28 July 2017

 

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