Chagas' disease and the autoimmunity hypothesis (Q33588893)

28 July 2017

1 reference

title

Chagas' disease and the autoimmunity hypothesis (English)

1 reference

28 July 2017

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F Kierszenbaum

1

1 reference

28 July 2017

language of work or name

English

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publication date

1 April 1999

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Clinical Microbiology Reviews

28 July 2017

published in

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28 July 2017

volume

12

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28 July 2017

issue

2

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28 July 2017

page(s)

210-223

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Autoimmunity in chagas disease cardiomyopathy: Fulfilling the criteria at last?

28 July 2017

cites work

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Antibodies to ribosomal P proteins of Trypanosoma cruzi in Chagas disease possess functional autoreactivity with heart tissue and differ from anti-P autoantibodies in lupus

21 June 2018

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21 June 2018

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21 June 2018

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Kinetoplast DNA signatures of Trypanosoma cruzi strains obtained directly from infected tissues

21 June 2018

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Structural and functional analysis of the B cell epitopes recognized by anti-receptor autoantibodies in patients with Chagas' disease

21 June 2018

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Autoimmunity in Chagas' disease. Identification of cardiac myosin-B13 Trypanosoma cruzi protein crossreactive T cell clones in heart lesions of a chronic Chagas' cardiomyopathy patient

21 June 2018

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Heart transplantation in Chagas' disease. 10 years after the initial experience

21 June 2018

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Comparison of the polymerase chain reaction with two classical parasitological methods for the diagnosis of Chagas disease in an endemic region of north-eastern Brazil

21 June 2018

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Chronic experimental Chagas' disease: functional syngeneic T-B-cell cooperation in vitro in the absence of an exogenous stimulus

21 June 2018

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Heart transplantation for chronic Chagas' heart disease.

21 June 2018

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Studies of the coronary circulation in Chagas' heart disease

21 June 2018

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Heart transplantation for Chagas' cardiomyopathy

21 June 2018

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Trypanosoma cruzi: characterization of two recombinant antigens with potential application in the diagnosis of Chagas' disease

21 June 2018

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Antibodies to laminin and immunohistochemical localization of laminin in chronic chagasic cardiomyopathy: a review

21 June 2018

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Molecular mimicry between the immunodominant ribosomal protein P0 of Trypanosoma cruzi and a functional epitope on the human beta 1-adrenergic receptor

21 June 2018

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The challenge of chagasic cardiomyopathy. The pathologic roles of autonomic abnormalities, autoimmune mechanisms and microvascular changes, and therapeutic implications

21 June 2018

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FL-160 proteins of Trypanosoma cruzi are expressed from a multigene family and contain two distinct epitopes that mimic nervous tissues

21 June 2018

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Localization of a functional autoimmune epitope on the muscarinic acetylcholine receptor-2 in patients with idiopathic dilated cardiomyopathy

21 June 2018

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Autoimmunity in Chagas disease cardiopathy: biological relevance of a cardiac myosin-specific epitope crossreactive to an immunodominant Trypanosoma cruzi antigen.

21 June 2018

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Delayed hypersensitivity to heart antigens in Chagas' disease as measured by in vitro lymphocyte stimulation

21 June 2018

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Experimental Chagas' disease: kinetics of lymphocyte responses and immunological control of the transition from acute to chronic Trypanosoma cruzi infection

21 June 2018

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Immunity to Trypanosoma cruzi

21 June 2018

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The relationship between autoimmunity and Chagas' disease: causal or coincidental?

21 June 2018

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Do self-heart-reactive T cells expand in Trypanosoma cruzi-immune hosts?

21 June 2018

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Antiheart antibody-dependent cytotoxicity in the sera of mice chronically infected with Trypanosoma cruzi.

21 June 2018

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Autoimmunity in Chagas' disease

21 June 2018

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Persistence of polyclonal B cell activation with undetectable parasitemia in late stages of experimental Chagas' disease.

21 June 2018

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Eosinophil activation in acute and chronic chagasic myocardial lesions and deposition of toxic eosinophil granule proteins on heart myofibers.

21 June 2018

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Interaction of human eosinophils or neutrophils with Trypanosoma cruzi in vitro causes bystander cardiac cell damage

21 June 2018

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Immunobiology of murine T. cruzi infection: the predominance of parasite-nonspecific responses and the activation of TCRI T cells

21 June 2018

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Trypanosoma cruzi: cross-reactive anti-heart autoantibodies produced during infection in mice.

21 June 2018

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Autoimmunity and Chagas' disease

21 June 2018

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Anti-myosin humoral immune response following cardiac injury

21 June 2018

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Identification of major Trypanosoma cruzi antigenic determinants in chronic Chagas' heart disease

21 June 2018

1 reference

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Autoimmunity in Chagas' disease: specific inhibition of reactivity of CD4+ T cells against myosin in mice chronically infected with Trypanosoma cruzi.

21 June 2018

1 reference

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Fl-160. A surface antigen of Trypanosoma cruzi that mimics mammalian nervous tissue

21 June 2018

1 reference

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Serological activity against galactosyl-alpha(1-3)galactose in sera from patients with several kinetoplastida infections

21 June 2018

1 reference

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Circulating antibodies to mouse laminin in Chagas disease, American cutaneous leishmaniasis, and normal individuals recognize terminal galactosyl(alpha 1-3)-galactose epitopes

21 June 2018

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Cardiac myosin-induced myocarditis. Heart autoantibodies are not involved in the induction of the disease

21 June 2018

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Trypanosoma cruzi: antibodies to a MAP-like protein in chronic Chagas' disease cross-react with mammalian cytoskeleton

21 June 2018

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Natural anti-Gal antibodies prevent, rather than cause, autoimmunity in human Chagas' disease

21 June 2018

1 reference

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Humoral autoimmune response to ribosomal P proteins in chronic Chagas heart disease

21 June 2018

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Mimicry in Trypanosoma cruzi: fantasy and reality

21 June 2018

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Anti-CD4 abrogates rejection and reestablishes long-term tolerance to syngeneic newborn hearts grafted in mice chronically infected with Trypanosoma cruzi

21 June 2018

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Molecular mimicry by Trypanosoma cruzi: the F1-160 epitope that mimics mammalian nerve can be mapped to a 12-amino acid peptide

21 June 2018

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Major Trypanosoma cruzi antigenic determinant in Chagas' heart disease shares homology with the systemic lupus erythematosus ribosomal P protein epitope

21 June 2018

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Trypanosoma cruzi attachment to lymphocyte muscarinic cholinergic and beta adrenergic receptors modulates intracellular signal transduction

21 June 2018

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Chronic chagasic myocarditis pathogenesis: dependence on autoimmune and microvascular factors

21 June 2018

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Characterization of the C-terminal region of a Trypanosoma cruzi 38-kDa ribosomal P0 protein that does not react with lupus anti-P autoantibodies

21 June 2018

1 reference

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Cloning and expression of Trypanosoma cruzi ribosomal protein P0 and epitope analysis of anti-P0 autoantibodies in Chagas' disease patients

21 June 2018

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Molecular mimicry between Trypanosoma cruzi and host nervous tissues

21 June 2018

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Autoantibodies to the ribosomal P proteins react with a plasma membrane-related target on human cells

21 June 2018

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Autonomic neuropathy and immunological abnormalities in Chagas' disease

21 June 2018

1 reference

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Investigation of the EVI antibody in parasitic diseases other than American trypanosomiasis. An anti-skeletal muscle antibody in leishmaniasis

21 June 2018

1 reference

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Effect of chagasic sera on the rat isolated atrial preparation: immunological, morphological and function aspects

21 June 2018

1 reference

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Mechanisms of resistance against experimental Trypanosoma cruzi infection: the importance of antibodies and antibody-forming capacity in the Biozzi high and low responder mice

21 June 2018

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Protective effects of specific antibodies in Trypanosoma cruzi infections

21 June 2018

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Immunosuppression and circulating Trypanosoma cruzi in a kidney transplant recipient

21 June 2018

1 reference

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Trypanosoma cruzi: in vitro induction of macrophage microbicidal activity

21 June 2018

1 reference

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Circulating antibodies to peripheral nerve in American trypanosomiasis (Chagas' disease)

21 June 2018

1 reference

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American trypanosomiasis: Chagas' disease

21 June 2018

1 reference

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Effects of complement depletion in experimental chagas disease: immune lysis of virulent blood forms of Trypanosoma cruzi

21 June 2018

1 reference

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[Triatoma infestans: importance, control and elimination of the species in the state of São Paulo, Brazil]

21 June 2018

1 reference

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Aortic endothelial cell changes in the acute septicemic phase of experimental Trypanosoma cruzi infection in rats: scanning and transmission electron microscopic study

31 October 2018

1 reference

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[Evaluation of vectors of Chagas' disease eradication programs in Chile by serological study of children under 10 years old]

31 October 2018

1 reference

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Involvement of laminin and its receptor in abrogation of heart graft rejection by autoreactive T cells from Trypanosoma cruzi-infected mice

31 October 2018

1 reference

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Desensitization and sequestration of human m2 muscarinic acetylcholine receptors by autoantibodies from patients with Chagas' disease

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Human chagasic disease is not associated with an antiheart humoral response

10 December 2018

1 reference

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Interaction of human chagasic IgG with the second extracellular loop of the human heart muscarinic acetylcholine receptor: functional and pathological implications

10 December 2018

1 reference

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Chagas' disease: enhancement of systemic inflammatory reaction in cyclophosphamide treated mice

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Antibodies from Trypanosoma cruzi infected mice recognize the second extracellular loop of the beta 1-adrenergic and M2-muscarinic receptors and regulate calcium channels in isolated cardiomyocytes

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

PCR detection of Trypanosoma cruzi DNA in oesophageal tissues of patients with chronic digestive Chagas' disease

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Prevalence of anti-R-13 antibodies in human Trypanosoma cruzi infection

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Compromised microcirculation in acute murine Trypanosoma cruzi infection

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

In vivo detection of Trypanosoma cruzi antigens in hearts of patients with chronic Chagas' heart disease

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Reactivation of experimental chronic T cruzi infection after immunosuppressive treatment by cyclosporine A and betametasone

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Autoantibodies in Chagas' disease. An antibody cross-reactive with human and Trypanosoma cruzi ribosomal proteins

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Amplification of a Trypanosoma cruzi DNA sequence from inflammatory lesions in human chagasic cardiomyopathy

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Cardiac antigen-specific autoantibody production is associated with cardiomyopathy in Trypanosoma cruzi-infected mice

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Immunohistochemical localization of laminin in the hearts of patients with chronic chagasic cardiomyopathy: relationship to thickening of basement membranes

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Trypanosoma cruzi: recognition of a 43-kDa muscle glycoprotein by autoantibodies present during murine infection

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Identification of antibodies with muscarinic cholinergic activity in human Chagas' disease: pathological implications

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Presence of antiheart and antiskeletal muscle glycolipid autoantibodies in the sera of patients with chagasic cardiopathy

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Enhanced myocardial lesions in chronically Trypanosoma cruzi-infected rats subjected to adult thymectomy

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Use of a simplified polymerase chain reaction procedure to detect Trypanosoma cruzi in blood samples from chronic chagasic patients in a rural endemic area

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Trypanosoma cruziinfection enhances polyreactive antibody response in an acute case of human Chagas' disease

10 December 2018

1 reference

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The chronic presence of the parasite, and anti-P autoimmunity in Chagas disease: the Trypanosoma cruzi ribosomal P proteins, and their recognition by the host immune system

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Chagas' disease cardioneuropathy: association of anti-Trypanosoma cruzi and anti-sciatic nerve antibodies

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Detection of parasite DNA in Chagas' heart disease

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Role of inflammatory cells in Chagas' disease. II. Interactions of mouse macrophages and human monocytes with intracellular forms of Trypanosoma cruzi: uptake and mechanism of destruction

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Role of inflammatory cells in Chagas' disease. I. Uptake and mechanism of destruction of intracellular (amastigote) forms of Trypanosoma cruzi by human eosinophils

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Heterophil nature of EVI antibody in Trypanosoma cruzi infection

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Role of polymorphonuclear cells in Chagas' disease. I. Uptake and mechanisms of destruction of intracellular (amastigote) forms of Trypanosoma cruzi by human neutrophils

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

A circulating IgG in Chagas' disease which binds to beta-adrenoceptors of myocardium and modulates their activity

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

The effects of some immunosuppressive agents in experimental chronic Chagas's disease

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Phagocytosis: a defense mechanism against infection with Trypanosoma cruzi

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Antibodies against endocardium, vascular structures, and interstitium of striated muscle that cross-react with T. cruzi and T. rhodesiense

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Chagasic cardiopathy. Demonstration of a serum gamma globulin factor which reacts with endocardium and vascular structures

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Very large and isotypically atypical polyclonal plaque-forming cell responses in mice infected with Trypanosoma cruzi

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

A histopathological analysis of the course of myocarditis in C3H/He mice infected with Trypanosoma cruzi clone Sylvio-X10/4

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

A study of human myocardial tissue in Chagas' disease: distribution and frequency of inflammatory cell types

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Studies of Trypanosoma cruzi clones in inbred mice. III. Histopathological and electrocardiographical responses to chronic infection

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Role of inflammatory cells in Chagas' disease. III. Kinetics of human eosinophil activation upon interaction with parasites (Trypanosoma cruzi)

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Suppression of polyclonal antibody production in Trypanosoma cruzi-infected mice by treatment with anti-L3T4 antibodies

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Neuropathy associated with experimental Chagas' disease

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

L3T4+ T cells able to mediate parasite-specific delayed-type hypersensitivity play a role in the pathology of experimental Chagas' disease

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Human chagasic IgG interacting with lymphocyte neurotransmitter receptors triggers intracellular signal transduction

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Microvascular changes as a cause of chronic cardiomyopathy in Chagas' disease

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Acute CNS infection by Trypanosoma cruzi (Chagas' disease) in immunosuppressed patients

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Presence of cells producing antiheart autoantibodies in the inflammatory infiltrate of chronic chagasic myocarditis

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

CD5 B cells. Potential role in the (auto)immune responses to Trypanosoma cruzi infection

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Cross-reactivity of lytic antibodies against blood forms of Trypanosoma cruzi

10 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=88915

Effects of human colony-stimulating factor on the uptake and destruction of a pathogenic parasite (Trypanosoma cruzi) by human neutrophils.

10 December 2018

1 reference

12 December 2020

In chronic Chagas heart disease, don't forget the parasite

1 reference

12 December 2020

Is there autoimmunity in Chagas disease?

1 reference

12 December 2020

The mechanisms of Trypanosoma cruzi invasion of mammalian cells

1 reference

12 December 2020

TRANSPLANTATION OF CARDIAC TISSUE INTO THE MOUSE EAR

1 reference

12 December 2020

Chronic chagasic tissue lesions in the absence of Trypanosoma cruzi: a proposed mechanism

1 reference

12 December 2020

Cardiac parasympathetic abnormalities: Cause or consequence of chagas heart disease?

1 reference

12 December 2020

Identifiers

PMC publication ID

88915

1 reference

28 July 2017

1 reference