Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation (Q33591785)

28 July 2017

title

Isolated C-terminal tail of FGF23 alleviates hypophosphatemia by inhibiting FGF23-FGFR-Klotho complex formation (English)

1 reference

Fibroblast growth factor receptor 4

28 July 2017

main subject

1 reference

Fibroblast growth factor receptor 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Klotho

1 reference

GOA release 2020-03-11

Regina Goetz

1

0 references

Moosa Mohammadi

object named as

Moosa Mohammadi

12

0 references

Makoto Kuro-o

11

object named as

Makoto Kuro-o

1 reference

28 July 2017

10

Orson W Moe

1 reference

28 July 2017

4

Hiroshi Kurosu

1 reference

28 July 2017

8

Anna V Eliseenkova

1 reference

28 July 2017

Yuji Nakada

2

1 reference

28 July 2017

Ming Chang Hu

3

1 reference

28 July 2017

Lei Wang

5

1 reference

28 July 2017

Teruyo Nakatani

6

1 reference

28 July 2017

Mingjun Shi

7

1 reference

28 July 2017

Mohammed S Razzaque

9

1 reference

28 July 2017

language of work or name

English

0 references

publication date

4 December 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

published in

1 reference

28 July 2017

volume

107

1 reference

28 July 2017

issue

1

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28 July 2017

page(s)

407-412

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Inactivation of klotho function induces hyperphosphatemia even in presence of high serum fibroblast growth factor 23 levels in a genetically engineered hypophosphatemic (Hyp) mouse model

28 July 2017

cites work

1 reference

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Initial FGF23-mediated signaling occurs in the distal convoluted tubule

21 June 2018

1 reference

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Molecular genetic and biochemical analyses of FGF23 mutations in familial tumoral calcinosis

21 June 2018

1 reference

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Calcimimetics as an adjuvant treatment for familial hypophosphatemic rickets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1alpha-hydroxylase expression in vitro

21 June 2018

1 reference

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Hereditary hypophosphatemias: new genes in the bone-kidney axis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Hypophosphatemia: clinical consequences and management

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Molecular insights into the klotho-dependent, endocrine mode of action of fibroblast growth factor 19 subfamily members

21 June 2018

1 reference

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Klotho converts canonical FGF receptor into a specific receptor for FGF23

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Regulation of fibroblast growth factor-23 signaling by klotho

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Hypophosphatemia: an update on its etiology and treatment

21 June 2018

1 reference

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Suppression of aging in mice by the hormone Klotho

21 June 2018

1 reference

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Fibroblast growth factor 23: roles in health and disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Circulating concentration of FGF-23 increases as renal function declines in patients with chronic kidney disease, but does not change in response to variation in phosphate intake in healthy volunteers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Effect of hydrolysis-resistant FGF23-R179Q on dietary phosphate regulation of the renal type-II Na/Pi transporter

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Serum phosphate abnormalities in the emergency department

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Fibroblast growth factor (FGF)-23 inhibits renal phosphate reabsorption by activation of the mitogen-activated protein kinase pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23

21 June 2018

1 reference

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Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia

21 June 2018

1 reference

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The autosomal dominant hypophosphatemic rickets (ADHR) gene is a secreted polypeptide overexpressed by tumors that cause phosphate wasting

21 June 2018

1 reference

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Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Identification of the human klotho gene and its two transcripts encoding membrane and secreted klotho protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Mutation of the mouse klotho gene leads to a syndrome resembling ageing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Pex/PEX tissue distribution and evidence for a deletion in the 3' region of the Pex gene in X-linked hypophosphatemic mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Intravenous phosphate repletion regimen for critically ill patients with moderate hypophosphatemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

A gene (PEX) with homologies to endopeptidases is mutated in patients with X-linked hypophosphatemic rickets. The HYP Consortium

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Severe Hypophosphatemia in Postoperative Patients

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Hypophosphatemia: mouse model for human familial hypophosphatemic (vitamin D-resistant) rickets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Therapeutic effects of anti-FGF23 antibodies in hypophosphatemic rickets/osteomalacia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

FGF23 elevation and hypophosphatemia after intravenous iron polymaltose: a prospective study

31 October 2018

1 reference

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Anti-FGF23 neutralizing antibodies show the physiological role and structural features of FGF23.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Tumor producing fibroblast growth factor 23 localized by two-staged venous sampling

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Tumor-Induced Osteomalacia

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Effect of fibroblast growth factor-23 on phosphate transport in proximal tubules

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

A novel mutation in fibroblast growth factor 23 gene as a cause of tumoral calcinosis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Immunohistochemical localization of Klotho protein in brain, kidney, and reproductive organs of mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Transgenic mice expressing fibroblast growth factor 23 under the control of the alpha1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Mutant FGF-23 responsible for autosomal dominant hypophosphatemic rickets is resistant to proteolytic cleavage and causes hypophosphatemia in vivo.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Pex gene deletions in Gy and Hyp mice provide mouse models for X-linked hypophosphatemia

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806769

Large phosphate shifts with treatment for hyperglycemia

31 October 2018

1 reference

12 December 2020

Post-transplant hypophosphatemia: Tertiary 'Hyper-Phosphatoninism'?

1 reference

12 December 2020

Fibroblast Growth Factor 23 (FGF23) Predicts Progression of Chronic Kidney Disease: The Mild to Moderate Kidney Disease (MMKD) Study

1 reference

12 December 2020

Two novel GALNT3 mutations in familial tumoral calcinosis

1 reference

12 December 2020

Establishment of the anti-Klotho monoclonal antibodies and detection of Klotho protein in kidneys

1 reference

12 December 2020

Intravenous phosphate in the intensive care unit: more aggressive repletion regimens for moderate and severe hypophosphatemia

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0902006107

1 reference

release_wmzcib57lfhhzgzrxurccv5n4e

28 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/wmzcib57lfhhzgzrxurccv5n4e

24 November 2022

mapped directly with Wikidata item

PMC publication ID

2806769

1 reference

28 July 2017

1 reference