The Erythropoietin Receptor: Structure, Activation and Intracellular Signal Transduction. (Q33632893)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322390%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

title

The Erythropoietin Receptor: Structure, Activation and Intracellular Signal Transduction (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322390%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

1 reference

Stefan N Constantinescu

series ordinal

1

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7 December 2019

3

Lodish HF

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7 December 2019

Ghaffari S

2

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7 December 2019

publication date

1 December 1999

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322390%20AND%20SRC:MED&resulttype=core&format=json

Trends in Endocrinology and Metabolism

7 December 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10322390%20AND%20SRC:MED&resulttype=core&format=json

7 December 2019

volume

10

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7 December 2019

issue

1

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7 December 2019

page(s)

18-23

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Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor

7 December 2019

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Small peptides as potent mimetics of the protein hormone erythropoietin

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JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin

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Interaction of the erythropoietin and stem-cell-factor receptors

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Identification of a cytoplasmic motif in the erythropoietin receptor required for receptor internalization

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An alpha-helical signal in the cytosolic domain of the interleukin 2 receptor beta chain mediates sorting towards degradation after endocytosis

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Activation of the erythropoietin (EPO) receptor by bivalent anti-EPO receptor antibodies

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Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity

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An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: A cytokine receptor superfamily oncogene

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Malignant transformation of erythroid cells in vivo by introduction of a nonreplicating retrovirus vector.

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Activation of cell growth by binding of Friend spleen focus-forming virus gp55 glycoprotein to the erythropoietin receptor

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7 January 2021

Transmembrane domain of the envelope gene of a polycythemia-inducing retrovirus determines erythropoietin-independent growth

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7 January 2021

The erythropoietin receptor transmembrane region is necessary for activation by the Friend spleen focus-forming virus gp55 glycoprotein

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7 January 2021

Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop

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Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

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Jak2 is essential for signaling through a variety of cytokine receptors

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7 January 2021

In vitro phosphorylation of the erythropoietin receptor and an associated protein, pp130

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7 January 2021

Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells

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7 January 2021

Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and Stat5 activation.

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7 January 2021

Multiple tyrosine residues in the cytosolic domain of the erythropoietin receptor promote activation of STAT5.

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7 January 2021

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7 January 2021

Phosphorylation of tyrosine 503 in the erythropoietin receptor (EpR) is essential for binding the P85 subunit of phosphatidylinositol (PI) 3-kinase and for EpR-associated PI 3-kinase activity

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7 January 2021

Identification of a novel pathway important for proliferation and differentiation of primary erythroid progenitors

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7 January 2021

Tyrosine Residues within the Intracellular Domain of the Erythropoietin Receptor Mediate Activation of AP-1 Transcription Factors

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7 January 2021

AP1 regulation of proliferation and initiation of apoptosis in erythropoietin-dependent erythroid cells

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7 January 2021

The prolactin receptor and severely truncated erythropoietin receptors support differentiation of erythroid progenitors

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7 January 2021

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

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7 January 2021

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7 January 2021

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Bcl-2 Rescues T Lymphopoiesis in Interleukin-7 Receptor–Deficient Mice

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7 January 2021

Functional interaction of erythropoietin and stem cell factor receptors is essential for erythroid colony formation

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7 January 2021