The rationale for corticotropin-releasing hormone receptor (CRH-R) antagonists to treat depression and anxiety (Q33658043)

28 July 2017

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title

The rationale for corticotropin-releasing hormone receptor (CRH-R) antagonists to treat depression and anxiety (English)

1 reference

28 July 2017

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Holsboer F

1

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28 July 2017

publication date

1 May 1999

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Journal of Psychiatric Research

28 July 2017

published in

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28 July 2017

volume

33

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28 July 2017

issue

3

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28 July 2017

page(s)

181-214

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Regulation of pituitary ACTH secretion during chronic stress

28 July 2017

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7 January 2021

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https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Effects of corticotropin-releasing factor on brain serotonergic activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Increased number of vasopressin- and oxytocin-expressing neurons in the paraventricular nucleus of the hypothalamus in depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Regulation of pituitary corticotropin releasing hormone (CRH) receptor mRNA and CRH binding during adrenalectomy: role of glucocorticoids and hypothalamic factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

New biochemical hypotheses on the mechanism of action of antidepressant drugs: cAMP-dependent phosphorylation system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Microinjection of a corticotropin-releasing factor antagonist into the central nucleus of the amygdala reverses anxiogenic-like effects of ethanol withdrawal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

DNA binding of the glucocorticoid receptor is not essential for survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Prenatal immune challenge alters the hypothalamic-pituitary-adrenocortical axis in adult rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Hypothalamic-pituitary-adrenocortical axis changes in the rat after long-term treatment with the reversible monoamine oxidase-A inhibitor moclobemide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Unexpected inhibitory action of N-methyl-D,L-aspartate or luteinizing hormone release in adult ovariectomized rhesus monkeys: a role of the hypothalamic-adrenal axis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Resolving GABAA/benzodiazepine receptors: cellular and subcellular localization in the CNS with monoclonal antibodies.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Immune challenge and immobilization stress induce transcription of the gene encoding the CRF receptor in selective nuclei of the rat hypothalamus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Synthetic Competitive Antagonists of Corticotropin-Releasing Factor: Effect on ACTH Secretion in the Rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Activation of corticotropin-releasing factor in the limbic system during cannabinoid withdrawal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Evidence for the involvement of corticotrophin-releasing hormone in the pathogenesis of traumatic brain injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Antidepressants restore hypothalamic-pituitary-adrenal feedback function in aged, cognitively-impaired rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

The corticotropin-releasing hormone stimulation test in patients with panic disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

A microdialysis examination of serotonin release in the rat forebrain induced by behavioral/environmental manipulations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

The neuropsychopharmacological potential of neuroactive steroids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Immunohistochemical localization of gamma-aminobutyric acid in the rat pituitary gland and related hypothalamic regions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

CP-154,526: a potent and selective nonpeptide antagonist of corticotropin releasing factor receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Identification of a cyclic adenosine monophosphate-responsive element in the rat corticotropin-releasing hormone gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

CP-154,526, a selective, non-peptide antagonist of the corticotropin-releasing factor1 receptor attenuates stress-induced relapse to drug seeking in cocaine- and heroin-trained rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

ICV-CRH alters stress-induced freezing behavior without affecting pain sensitivity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Increase in cortical and midbrain tryptophan hydroxylase activity by intracerebroventricular administration of corticotropin releasing factor: block by adrenalectomy, by RU 38486 and by bilateral lesions to the central nucleus of the amygdala

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Regulation of lordosis behaviour in the female rat by corticotropin-releasing factor, beta-endorphin/corticotropin and luteinizing hormone-releasing hormone neuronal systems in the medial preoptic area

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Corticotropin-releasing hormone (CRH) antisense oligodeoxynucleotide induces anxiolytic effects in rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Corticotropin-releasing hormone (CRH) antisense oligodeoxynucleotide treatment attenuates social defeat-induced anxiety in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Corticotropin-releasing hormone receptor (type I) antisense targeting reduces anxiety

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Trimipramine and imipramine exert different effects on the sleep EEG and on nocturnal hormone secretion during treatment of major depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Appetite-suppressing effects of urocortin, a CRF-related neuropeptide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Identification of a novel murine receptor for corticotropin-releasing hormone expressed in the heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Overproduction of corticotropin-releasing factor in transgenic mice: a genetic model of anxiogenic behavior.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Corticotrophin-releasing factor antagonist inhibits neuronal damage induced by focal cerebral ischaemia or activation of NMDA receptors in the rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Mode of action of antidepressant drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Corticotropin releasing factor produces behavioural activation in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Differential steroid hormone and neural influences on peptide mRNA levels in CRH cells of the paraventricular nucleus: a hybridization histochemical study in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Organization of ovine corticotropin-releasing factor immunoreactive cells and fibers in the rat brain: an immunohistochemical study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Potentiation of acoustic startle by corticotropin-releasing factor (CRF) and by fear are both reversed by alpha-helical CRF (9-41).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Attenuation of stress-induced behavior by antagonism of corticotropin-releasing factor receptors in the central amygdala in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Corticotropin-releasing factor stimulates Ca2+ influx in cultured rat astrocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

A new functional isoform of the human CRF2 receptor for corticotropin-releasing factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Corticotropin-releasing factor: evidence for a neurotransmitter role in the locus ceruleus during hemodynamic stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Corticotropin-releasing factor activates noradrenergic neurons of the locus coeruleus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

The locus coeruleus as a site for integrating corticotropin-releasing factor and noradrenergic mediation of stress responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Corticotropin-releasing factor-containing axon terminals synapse onto catecholamine dendrites and may presynaptically modulate other afferents in the rostral pole of the nucleus locus coeruleus in the rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Primary structure and functional expression of mouse pituitary and human brain corticotrophin releasing factor receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Cortisol response to a combined dexamethasone-human corticotrophin-releasing hormone challenge in patients with depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Effect of age on the cortisol response to human corticotropin-releasing hormone in depressed patients pretreated with dexamethasone

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Combined administration of human corticotropin-releasing factor and lysine vasopressin induces cortisol escape from dexamethasone suppression in healthy subjects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Blunting of ACTH response to human CRH in depressed patients is avoided by metyrapone pretreatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Human CRH stimulation response during acute withdrawal and after medium-term abstention from alcohol abuse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

The effect of repeated human corticotropin-releasing hormone administration on dexamethasone-suppressed pituitary-adrenocortical activity in healthy subjects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Behavioural activation produced by CRH but not alpha-helical CRH (CRH-receptor antagonist) when microinfused into the central nucleus of the amygdala under stress-free conditions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

The validity of animal models of depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Evidence against changes in corticotroph CRF receptors in depressed patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

Prediction of medium-term outcome by cortisol response to the combined dexamethasone-CRH test in patients with remitted depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

The role of corticotropin-releasing hormone in the pathogenesis of Cushing's disease, anorexia nervosa, alcoholism, affective disorders and dementia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

inferred from DOI database lookup

7 January 2021

based on heuristic

Phorbol ester and calcium regulation of corticotrophin-releasing factor receptor 1 expression in a neuronal cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3956%2898%2990056-5

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0022-3956(98)90056-5

1 reference

28 July 2017

1 reference