Genetic characterization of HIV type 1 Nef-induced vesicle secretion (Q33714550)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20156100%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Genetic characterization of HIV type 1 Nef-induced vesicle secretion (English)

1 reference

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18 January 2020

7

1 reference

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18 January 2020

8

Francois Villinger

1 reference

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18 January 2020

author name string

Syed A Ali

1

1 reference

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18 January 2020

Ming-Bo Huang

2

1 reference

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18 January 2020

Patrick E Campbell

3

1 reference

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18 January 2020

William W Roth

4

1 reference

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18 January 2020

Tamika Campbell

5

1 reference

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18 January 2020

Mahfuz Khan

6

1 reference

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18 January 2020

Michael D Powell

9

1 reference

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18 January 2020

Vincent C Bond

10

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18 January 2020

publication date

1 February 2010

1 reference

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AIDS Research and Human Retroviruses

18 January 2020

published in

1 reference

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18 January 2020

volume

26

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18 January 2020

issue

2

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18 January 2020

page(s)

173-192

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Determinants in HIV-1 Nef for enhancement of virus replication and depletion of CD4+ T lymphocytes in human lymphoid tissue ex vivo

18 January 2020

cites work

1 reference

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Endosome protein sorting: motifs and machinery

21 June 2018

1 reference

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Discrimination between exosomes and HIV-1: purification of both vesicles from cell-free supernatants

21 June 2018

1 reference

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HIV-1 Nef protein is secreted into vesicles that can fuse with target cells and virions

21 June 2018

1 reference

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CD45 immunoaffinity depletion of vesicles from Jurkat T cells demonstrates that exosomes contain CD45: no evidence for a distinct exosome/HIV-1 budding pathway

21 June 2018

1 reference

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Microparticles are vectors of paradoxical information in vascular cells including the endothelium: role in health and diseases

21 June 2018

1 reference

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Tumor exosomes inhibit differentiation of bone marrow dendritic cells

21 June 2018

1 reference

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Activation/proliferation and apoptosis of bystander goat lymphocytes induced by a macrophage-tropic chimeric caprine arthritis encephalitis virus expressing SIV Nef.

21 June 2018

1 reference

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Specific and distinct determinants mediate membrane binding and lipid raft incorporation of HIV-1(SF2) Nef.

21 June 2018

1 reference

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Functional characterization of HIV-1 Nef mutants in the context of viral infection

21 June 2018

1 reference

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RETRACTED: Pregnancy-associated exosomes and their modulation of T cell signaling

21 June 2018

1 reference

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The platelet microparticle proteome

21 June 2018

1 reference

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Characterization of Nef-CXCR4 interactions important for apoptosis induction

21 June 2018

1 reference

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Membrane targeting of lipid modified signal transduction proteins.

21 June 2018

1 reference

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CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

21 June 2018

1 reference

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Primary HIV-1 infection is associated with preferential depletion of CD4+ T lymphocytes from effector sites in the gastrointestinal tract

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Exosomes: endosomal-derived vesicles shipping extracellular messages

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Extracellular Nef protein targets CD4+ T cells for apoptosis by interacting with CXCR4 surface receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Severe CD4+ T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Blood-brain barrier changes during invasion of the central nervous system by HIV-1. Old and new insights into the mechanism

21 June 2018

1 reference

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In vivo evolution of human immunodeficiency virus type 1 toward increased pathogenicity through CXCR4-mediated killing of uninfected CD4 T cells

21 June 2018

1 reference

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Exogenous Nef protein activates NF-kappa B, AP-1, and c-Jun N-terminal kinase and stimulates HIV transcription in promonocytic cells. Role in AIDS pathogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

The protein-tyrosine phosphatase CD45 reaches the cell surface via golgi-dependent and -independent pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Cardiac disease in transgenic mice expressing human immunodeficiency virus-1 nef in cells of the immune system

21 June 2018

1 reference

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Expression of simian immunodeficiency virus nef in immune cells of transgenic mice leads to a severe AIDS-like disease

21 June 2018

1 reference

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The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck.

21 June 2018

1 reference

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Structure--function relationships in HIV-1 Nef.

21 June 2018

1 reference

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Differential incorporation of CD45, CD80 (B7-1), CD86 (B7-2), and major histocompatibility complex class I and II molecules into human immunodeficiency virus type 1 virions and microvesicles: implications for viral pathogenesis and immune regulation

21 June 2018

1 reference

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Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles

21 June 2018

1 reference

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Identification of a potential HIV-induced source of bystander-mediated apoptosis in T cells: upregulation of trail in primary human macrophages by HIV-1 tat.

21 June 2018

1 reference

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HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell

21 June 2018

1 reference

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Chemokine-receptor activation by env determines the mechanism of death in HIV-infected and uninfected T lymphocytes.

21 June 2018

1 reference

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Highly restricted spread of HIV-1 and multiply infected cells within splenic germinal centers

21 June 2018

1 reference

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HIV-1 Nef protein binds to the cellular protein PACS-1 to downregulate class I major histocompatibility complexes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Fatty acylation of proteins: new insights into membrane targeting of myristoylated and palmitoylated proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. A report from the Sydney Blood Bank Cohort

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Structure of the anchor-domain of myristoylated and non-myristoylated HIV-1 Nef protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Rapid mucosal CD4(+) T-cell depletion and enteropathy in simian immunodeficiency virus-infected rhesus macaques

21 June 2018

1 reference

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Chronically HIV-1-infected monocytic cells induce apoptosis in cocultured T cells.

21 June 2018

1 reference

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CXCR4 and CD4 mediate a rapid CD95-independent cell death in CD4(+) T cells

21 June 2018

1 reference

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Virion incorporation of human immunodeficiency virus type 1 Nef is mediated by a bipartite membrane-targeting signal: analysis of its role in enhancement of viral infectivity.

21 June 2018

1 reference

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PACS-1 defines a novel gene family of cytosolic sorting proteins required for trans-Golgi network localization

21 June 2018

1 reference

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Grossly defective nef gene sequences in a human immunodeficiency virus type 1-seropositive long-term nonprogressor

21 June 2018

1 reference

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Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

21 June 2018

1 reference

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Distinct mechanisms trigger apoptosis in human immunodeficiency virus type 1-infected and in uninfected bystander T lymphocytes

21 June 2018

1 reference

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Death of bystander cells by a novel pathway involving early mitochondrial damage in human immunodeficiency virus-related lymphadenopathy.

21 June 2018

1 reference

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The anatomical basis of intestinal immunity

21 June 2018

1 reference

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The significance of shed membrane particles during programmed cell death in vitro, and in vivo, in HIV-1 infection

21 June 2018

1 reference

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Selective depletion of rectal lamina propria rather than lymphoid aggregate CD4 lymphocytes in HIV infection

21 June 2018

1 reference

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Nef proteins encoded by human and simian immunodeficiency viruses induce the accumulation of endosomes and lysosomes in human T cells

21 June 2018

1 reference

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In vitro cytocidal effects of human immunodeficiency virus type 1 Nef on unprimed human CD4+ T cells without MHC restriction

21 June 2018

1 reference

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Macrophage-dependent apoptosis of CD4+ T lymphocytes from HIV-infected individuals is mediated by FasL and tumor necrosis factor

21 June 2018

1 reference

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Clustered localization of oligomeric Nef protein of human immunodeficiency virus type 1 on the cell surface

21 June 2018

1 reference

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Human immunodeficiency virus type 1 Nef protein on the cell surface is cytocidal for human CD4+ T cells

21 June 2018

1 reference

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Soluble Nef antigen of HIV-1 is cytotoxic for human CD4+ T cells

21 June 2018

1 reference

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B lymphocytes secrete antigen-presenting vesicles

21 June 2018

1 reference

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Programmed cell death in peripheral lymphocytes from HIV-infected persons: increased susceptibility to apoptosis of CD4 and CD8 T cells correlates with lymphocyte activation and with disease progression.

21 June 2018

1 reference

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HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time

21 June 2018

1 reference

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Spontaneous and inducible epidermal hyperplasia in transgenic mice expressing HIV-1 Nef.

21 June 2018

1 reference

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Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene

21 June 2018

1 reference

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Type 1/type 2 cytokine modulation of T-cell programmed cell death as a model for human immunodeficiency virus pathogenesis

21 June 2018

1 reference

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The carboxyl-terminal region of HIV-1 Nef protein is a cell surface domain that can interact with CD4+ T cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

21 June 2018

1 reference

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Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

21 June 2018

1 reference

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A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity

21 June 2018

1 reference

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Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes

21 June 2018

1 reference

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Viral dynamics in human immunodeficiency virus type 1 infection

21 June 2018

1 reference

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Loss of CD4 T lymphocytes in patients infected with human immunodeficiency virus type 1 is more pronounced in the duodenal mucosa than in the peripheral blood. Berlin Diarrhea/Wasting Syndrome Study Group

21 June 2018

1 reference

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Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients

21 June 2018

1 reference

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HTLV-III expression in infected lymph nodes and relevance to pathogenesis of lymphadenopathy

21 June 2018

1 reference

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Reticulocyte maturation and exosome release: transferrin receptor containing exosomes shows multiple plasma membrane functions.

21 June 2018

1 reference

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Human immunodeficiency virus-infected individuals contain provirus in small numbers of peripheral mononuclear cells and at low copy numbers

21 June 2018

1 reference

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Importance of the nef gene for maintenance of high virus loads and for development of AIDS

21 June 2018

1 reference

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Detection of human immunodeficiency virus type 1 provirus in mononuclear cells by in situ polymerase chain reaction

21 June 2018

1 reference

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Role of myristoylation and N-terminal basic residues in membrane association of the human immunodeficiency virus type 1 Nef protein

21 June 2018

1 reference

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Peak SIV replication in resting memory CD4+ T cells depletes gut lamina propria CD4+ T cells.

30 October 2018

1 reference

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Human immunodeficiency virus type 1 (HIV-1) Nef activates STAT3 in primary human monocyte/macrophages through the release of soluble factors: involvement of Nef domains interacting with the cell endocytotic machinery

30 October 2018

1 reference

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Critical contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to apoptosis of human CD4+ T cells in HIV-1-infected hu-PBL-NOD-SCID mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Effect of extracellular human immunodeficiency virus type 1 glycoprotein 120 on primary human vascular endothelial cell cultures

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Expression of HIV-1 nef in yeast causes membrane perturbation and release of the myristylated Nef protein

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Differential susceptibility to activation-induced apoptosis among peripheral Th1 subsets: correlation with Bcl-2 expression and consequences for AIDS pathogenesis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

HIV type 1 Nef perturbs eye lens development in transgenic mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Antigen-stimulated apoptotic T-cell death in HIV infection is selective for CD4+ T cells, modulated by cytokines and effected by lymphotoxin.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Loss of mucosal CD4 lymphocytes is an early feature of HIV infection.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

Glomerulosclerosis and viral gene expression in HIV-transgenic mice: Role of nef

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2835390

HIV-1 Nef activates STAT1 in human monocytes/macrophages through the release of soluble factors

30 October 2018

1 reference

12 December 2020

Mutational analysis of the HIV nef protein

1 reference

12 December 2020

Involvement of HIV nef protein in abnormal hematopoiesis in AIDS: in vitro study on bone marrow progenitor cells

1 reference

12 December 2020

HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization

1 reference

12 December 2020

Nef modulation of HIV type 1 gene expression and cytopathicity in tissues of HIV transgenic mice

1 reference

12 December 2020

Dual role of HIV Tat in regulation of apoptosis in T cells

1 reference

12 December 2020

Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice

1 reference

12 December 2020

The implication of the chemokine receptor CXCR4 in HIV-1 envelope protein-induced apoptosis is independent of the G protein-mediated signalling

1 reference

12 December 2020

Identifiers

DOI

10.1089/AID.2009.0068

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20156100%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20156100%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

20156100

1 reference