Prion Protein-Hemin Interaction Upregulates Hemoglobin Synthesis: Implications for Cerebral Hemorrhage and Sporadic Creutzfeldt-Jakob Disease (Q33712255)

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English	Prion Protein-Hemin Interaction Upregulates Hemoglobin Synthesis: Implications for Cerebral Hemorrhage and Sporadic Creutzfeldt-Jakob Disease	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Prion Protein-Hemin Interaction Upregulates Hemoglobin Synthesis: Implications for Cerebral Hemorrhage and Sporadic Creutzfeldt-Jakob Disease (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

prion protein family

0 references

sporadic Creutzfeldt-Jakob disease

1 reference

based on heuristic

inferred from title

Ajai K. Tripathi

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26836195%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Neena Singh

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26836195%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

publication date

20 January 2016

1 reference

Europe PubMed Central

PubMed publication ID

28 July 2017

Journal of Alzheimer's Disease

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26836195%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

51

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26836195%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26836195%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

107-121

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26836195%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Prion protein functions as a ferrireductase partner for ZIP14 and DMT1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Prion protein promotes kidney iron uptake via its ferrireductase activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Brain immune cell composition and functional outcome after cerebral ischemia: comparison of two mouse strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Cellular prion protein and NMDA receptor modulation: protecting against excitotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

The anti-apoptotic role of neuroglobin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

A mitochondrial location for haemoglobins--dynamic distribution in ageing and Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Hemin uptake and release by neurons and glia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Prion protein regulates iron transport by functioning as a ferrireductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Heme transport and erythropoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Hemin augments growth and hemoglobinization of erythroid precursors from patients with diamond-blackfan anemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Review: Creutzfeldt-Jakob disease: prion protein type, disease phenotype and agent strain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Change in the characteristics of ferritin induces iron imbalance in prion disease affected brains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Targeting brain tumor stem cells with oncolytic adenoviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Hemoglobin expression in neurons and glia after intracerebral hemorrhage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Decreased CSF transferrin in sCJD: a potential pre-mortem diagnostic test for prion disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Analysis of the mitochondrial proteome in multiple sclerosis cortex

1 reference

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21 June 2018

Increased striatal injury and behavioral deficits after intracerebral hemorrhage in hemopexin knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Brain alpha- and beta-globin expression after intracerebral hemorrhage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Iron and porphyrin trafficking in heme biogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Neuronal low-density lipoprotein receptor-related protein 1 binds and endocytoses prion fibrils via receptor cluster 4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Hemin toxicity: a preventable source of brain damage following hemorrhagic stroke.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Context dependent neuroprotective properties of prion protein (PrP).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Unexpected expression of alpha- and beta-globin in mesencephalic dopaminergic neurons and glial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Neurons express hemoglobin alpha- and beta-chains in rat and human brains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Abnormal brain iron homeostasis in human and animal prion disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Heme-hemopexin complex attenuates neuronal cell death and stroke damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Effects of cerebral ischemia on neuronal hemoglobin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

A heme export protein is required for red blood cell differentiation and iron homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Hemin interactions and alterations of the subcellular localization of prion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Effect of heme oxygenase-1 on the vulnerability of astrocytes and neurons to hemoglobin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Heme as key regulator of major mammalian cellular functions: molecular, cellular, and pharmacological aspects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Recent advances in mammalian haem transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Regulation of globin gene transcription by heme in erythroleukemia cells: analysis of putative heme regulatory motifs in the p45 NF-E2 transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

A porphyrin increases survival time of mice after intracerebral prion infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Understanding alpha-globin gene regulation: Aiming to improve the management of thalassemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Overexpression of PrPC by adenovirus-mediated gene targeting reduces ischemic injury in a stroke rat model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Loss of alpha-hemoglobin-stabilizing protein impairs erythropoiesis and exacerbates beta-thalassemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Heme-dependent up-regulation of the alpha-globin gene expression by transcriptional repressor Bach1 in erythroid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Erythroid-induced commitment of K562 cells results in clusters of differentially expressed genes enriched for specific transcription regulatory elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Prion protein accumulation and neuroprotection in hypoxic brain damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Heme positively regulates the expression of beta-globin at the locus control region via the transcriptional factor Bach1 in erythroid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Heme and iron metabolism: role in cerebral hemorrhage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

The protein tyrosine phosphatase HePTP regulates nuclear translocation of ERK2 and can modulate megakaryocytic differentiation of K562 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

A novel erythroid-specific marker of transmissible spongiform encephalopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Iron protoporphyrin IX (hemin) but not tin or zinc protoporphyrin IX can stimulate gene expression in K562 cells from enhancer elements containing binding sites for NF-E2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Possible involvement of retinoid-like cofactor in serum in hemin/protoporphyrin-IX-induced differentiation of human leukemia K562 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Localization of specific erythropoietin binding sites in defined areas of the mouse brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Antioxidant protection by haemopexin of haem-stimulated lipid peroxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Modulation of ferritin H-chain expression in Friend erythroleukemia cells: transcriptional and translational regulation by hemin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

K562 human leukaemic cells synthesise embryonic haemoglobin in response to haemin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

21 June 2018

Uptake, metabolism and toxicity of hemin in cultured neurons

1 reference

https://api.crossref.org/works/10.3233%2FJAD-151039

21 January 2018

The putative heme transporter HCP1 is expressed in cultured astrocytes and contributes to the uptake of hemin.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-151039

21 January 2018

Cellular prion protein is increased in the plasma and peri-infarcted brain tissue after acute stroke.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-151039

21 January 2018

Aggravation of ischemic brain injury by prion protein deficiency: role of ERK-1/-2 and STAT-1.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-151039

21 January 2018

Expression of hemoglobin in rodent neurons

1 reference

https://api.crossref.org/works/10.3233%2FJAD-151039

21 January 2018

Mutant prion protein-mediated aggregation of normal prion protein in the endoplasmic reticulum: implications for prion propagation and neurotoxicity

1 reference

https://api.crossref.org/works/10.3233%2FJAD-151039

21 January 2018

Identification of the receptor scavenging hemopexin-heme complexes

1 reference

https://api.crossref.org/works/10.3233%2FJAD-151039

21 January 2018

The low-density lipoprotein receptor-related protein 1 (LRP1) mediates the endocytosis of the cellular prion protein

1 reference

https://api.crossref.org/works/10.3233%2FJAD-151039

21 January 2018

Normal prion protein trafficking in cultured human erythroblasts

1 reference

https://api.crossref.org/works/10.3233%2FJAD-151039

21 January 2018

alpha-Hemoglobin stabilizing protein is not a suitable marker for a screening test for variant Creutzfeldt-Jakob disease.

1 reference

https://api.crossref.org/works/10.3233%2FJAD-151039

21 January 2018

Neuronal hemoglobin is reduced in Alzheimer's disease, argyrophilic grain disease, Parkinson's disease, and dementia with Lewy bodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

30 October 2018

HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

30 October 2018

A novel site of erythropoietin production. Oxygen-dependent production in cultured rat astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5439432

30 October 2018

Neuroglobin-prion protein interaction: what's the function?

1 reference

https://api.crossref.org/works/10.3233%2FJAD-151039

21 January 2018

Regulation of Expression of Ferritin H-chain and Transferrin Receptor by Protoporphyrin IX

1 reference

https://pubmed.ncbi.nlm.nih.gov/26836195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of cellular prion protein alters postischemic Erk1/2 phosphorylation but not Akt phosphorylation and protects against focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/26836195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A spectrophotometric method for measuring hemoglobin in erythroleukemic cells (K562)

1 reference

https://pubmed.ncbi.nlm.nih.gov/26836195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemin-induced acceleration of hemoglobin production in immature cultured erythroid cells: preferential enhancement of fetal hemoglobin

1 reference

https://pubmed.ncbi.nlm.nih.gov/26836195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hemin preferentially stimulates synthesis of alpha-globin in K562 human erythroleukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/26836195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LRP1 controls biosynthetic and endocytic trafficking of neuronal prion protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/26836195

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3233/JAD-151039

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26836195%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26836195%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26836195%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

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