A radical scavenger edaravone inhibits matrix metalloproteinase-9 upregulation and blood-brain barrier breakdown in a mouse model of prolonged cerebral hypoperfusion (Q33748058)

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English	A radical scavenger edaravone inhibits matrix metalloproteinase-9 upregulation and blood-brain barrier breakdown in a mouse model of prolonged cerebral hypoperfusion	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

A radical scavenger edaravone inhibits matrix metalloproteinase-9 upregulation and blood-brain barrier breakdown in a mouse model of prolonged cerebral hypoperfusion (English)

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Europe PubMed Central

PubMed publication ID

29 July 2017

1 reference

based on heuristic

inferred from title

blood–brain barrier

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based on heuristic

inferred from title

author name string

Nobukazu Miyamoto

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Loc-Duyen D Pham

2

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Europe PubMed Central

PubMed publication ID

29 July 2017

Takakuni Maki

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Anna C Liang

4

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Europe PubMed Central

PubMed publication ID

29 July 2017

Ken Arai

5

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Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

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publication date

10 May 2014

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Europe PubMed Central

PubMed publication ID

29 July 2017

Neuroscience Letters

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Europe PubMed Central

PubMed publication ID

29 July 2017

573

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Europe PubMed Central

PubMed publication ID

29 July 2017

40-45

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Mechanisms of oligodendrocyte regeneration from ventricular-subventricular zone-derived progenitor cells in white matter diseases

1 reference

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21 June 2018

Oligodendrogenesis after cerebral ischemia

1 reference

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Crosstalk between cerebral endothelium and oligodendrocyte

1 reference

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Oxidative stress interferes with white matter renewal after prolonged cerebral hypoperfusion in mice

1 reference

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21 June 2018

Age-related decline in oligodendrogenesis retards white matter repair in mice

1 reference

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21 June 2018

Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain

2 references

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21 June 2018

https://pubmed.ncbi.nlm.nih.gov/24820542

12 December 2020

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Biphasic mechanisms of neurovascular unit injury and protection in CNS diseases

1 reference

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Oligodendrocyte precursors induce early blood-brain barrier opening after white matter injury

1 reference

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The abluminal endothelial membrane in neurovascular remodeling in health and disease

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Blood-brain barrier integrity and glial support: mechanisms that can be targeted for novel therapeutic approaches in stroke

1 reference

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21 June 2018

Crosstalk between oligodendrocytes and cerebral endothelium contributes to vascular remodeling after white matter injury

1 reference

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Central nervous system pericytes in health and disease

1 reference

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Combination of reactive oxygen species and tissue-type plasminogen activator enhances the induction of gelatinase B in brain endothelial cells

1 reference

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The neurovascular unit, matrix proteases, and innate inflammation

1 reference

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Pericytes regulate the blood-brain barrier

1 reference

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Pericytes are required for blood-brain barrier integrity during embryogenesis

1 reference

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The science of stroke: mechanisms in search of treatments

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A critical assessment of edaravone acute ischemic stroke efficacy trials: is edaravone an effective neuroprotective therapy?

1 reference

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21 June 2018

Hemoglobin-induced oxidative stress contributes to matrix metalloproteinase activation and blood-brain barrier dysfunction in vivo

1 reference

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21 June 2018

Edaravone, a free radical scavenger, protects components of the neurovascular unit against oxidative stress in vitro

1 reference

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Oxidative stress disrupts oligodendrocyte maturation

1 reference

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An oligovascular niche: cerebral endothelial cells promote the survival and proliferation of oligodendrocyte precursor cells

1 reference

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Neuroprotective effects of edaravone-administration on 6-OHDA-treated dopaminergic neurons

1 reference

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The life, death, and replacement of oligodendrocytes in the adult CNS.

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A new penumbra: transitioning from injury into repair after stroke

1 reference

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The blood-brain barrier in health and chronic neurodegenerative disorders

1 reference

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Targeting MMPs in acute and chronic neurological conditions

1 reference

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Neuroprotective effects of edaravone: a novel free radical scavenger in cerebrovascular injury.

1 reference

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Astrocyte-endothelial interactions at the blood-brain barrier

1 reference

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Multiple roles for MMPs and TIMPs in cerebral ischemia

1 reference

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Mechanisms, challenges and opportunities in stroke

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Matrix metalloproteinases in neuroinflammation

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Rapid alteration of tau in oligodendrocytes after focal ischemic injury in the rat: involvement of free radicals

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Low glutathione levels in brain regions of aged rats.

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Edaravone attenuates white matter lesions through endothelial protection in a rat chronic hypoperfusion model.

1 reference

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Edaravone protects against MPP+ -induced cytotoxicity in rat primary cultured astrocytes via inhibition of mitochondrial apoptotic pathway

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Anti-apoptotic and neuroprotective effects of edaravone following transient focal ischemia in rats

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Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters

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Involvement of matrix metalloproteinase in thrombolysis-associated hemorrhagic transformation after embolic focal ischemia in rats

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Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia.

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Evaluation of glutathione localization in brain using 99mTc meso-HMPAO.

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30 October 2018

Effects of a novel free radical scavenger, MCl-186, on ischemic brain damage in the rat distal middle cerebral artery occlusion model.

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30 October 2018

Effects of matrix metalloproteinase-9 gene knock-out on morphological and motor outcomes after traumatic brain injury

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A mouse model of chronic cerebral hypoperfusion characterizing features of vascular cognitive impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/24820542

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Nitric oxide-induced apoptosis in cultured rat astrocytes: protection by edaravone, a radical scavenger

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Identifiers

10.1016/J.NEULET.2014.05.005

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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