Biologic and pharmacologic regulation of mammalian glutathione synthesis (Q33777922)

29 July 2017

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title

Biologic and pharmacologic regulation of mammalian glutathione synthesis (English)

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29 July 2017

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Griffith OW

1

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29 July 2017

publication date

1 November 1999

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Free Radical Biology and Medicine

29 July 2017

published in

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29 July 2017

volume

27

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29 July 2017

issue

9-10

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29 July 2017

page(s)

922-935

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

29 July 2017

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7 January 2021

Detection of thiyl radical adducts formed during hydroxyl radical- and peroxynitrite-mediated oxidation of thiols--a high resolution ESR spin-trapping study at Q-band (35 GHz)

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

NO-induced oxidative stress and glutathione metabolism in rodent and human cells

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Defenses against peroxynitrite

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7 January 2021

Cellular reducing equivalents and oxidative stress

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7 January 2021

Antioxidant and redox regulation of gene transcription

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7 January 2021

Study of gene regulation by NF-kappa B and AP-1 in response to reactive oxygen intermediates

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Structure, catalytic mechanism, and evolution of the glutathione transferases

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Efficacy of oral N-acetylcysteine in the treatment of acetaminophen overdose. Analysis of the national multicenter study (1976 to 1985)

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Nutritional and hormonal regulation of glutathione homeostasis

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Potential for selective modulation of glutathione in cancer chemotherapy

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Glutathione: an overview of biosynthesis and modulation

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Regulation of hepatic glutathione synthesis

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Role of the liver in interorgan homeostasis of glutathione and cyst(e)ine

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Regulation of gamma-glutamylcysteine utilization in erythrocytes

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Patients with genetic defects in the gamma-glutamyl cycle

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Cloning and nucleotide sequence of a full-length cDNA for human liver gamma-glutamylcysteine synthetase

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Cloning and sequencing of the cDNA for the light subunit of human liver gamma-glutamylcysteine synthetase and relative mRNA levels for heavy and light subunits in human normal tissues

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Mapping of the glutamate-cysteine ligase catalytic subunit gene (GLCLC) to human chromosome 6p12 and mouse chromosome 9D-E and of the regulatory subunit gene (GLCLR) to human chromosome 1p21-p22 and mouse chromosome 3H1-3

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Expression and purification of human gamma-glutamylcysteine synthetase

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Amino acid sequence of rat kidney glutathione synthetase

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

A single mouse glutathione synthetase gene encodes six mRNAs with different 5' ends

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Inactivation of glutathione reductase by 2-chloroethyl nitrosourea-derived isocyanates

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Roles of MRP2 and oatp1 in hepatocellular export of reduced glutathione.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Rapid and specific efflux of reduced glutathione during apoptosis induced by anti-Fas/APO-1 antibody

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Changes in the glutathione status of plasma, liver and muscle following exhaustive exercise in rats

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Hepatic thiol and glutathione efflux under the influence of vasopressin, phenylephrine and adrenaline

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Proximal 5′-Flanking Sequence of the Human γ-Glutamylcysteine Synthetase Heavy Subunit Gene Is Involved in Cisplatin-Induced Transcriptional Up-regulation in a Lung Cancer Cell Line SBC-3

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Regulation of human gamma-glutamylcysteine synthetase: co-ordinate induction of the catalytic and regulatory subunits in HepG2 cells

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Transcriptional Regulation of γ-Glutamylcysteine Synthetase-Heavy Subunit by Oxidants in Human Alveolar Epithelial Cells

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Expression of glutathione and gamma-glutamylcysteine synthetase mRNA is Jun dependent

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Identification of cis-acting DNA elements of the human gamma-glutamylcysteine synthetase heavy subunit gene

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Induction of γ-glutamylcysteine synthetase by cigarette smoke is associated with AP-1 in human alveolar epithelial cells

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Characterisation of gamma-glutamylcysteine synthetase-heavy subunit promoter: a critical role for AP-1.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Increased transcription of the regulatory subunit of gamma-glutamylcysteine synthetase in rat lung epithelial L2 cells exposed to oxidative stress or glutathione depletion

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Long exposure to high glucose concentration impairs the responsive expression of gamma-glutamylcysteine synthetase by interleukin-1beta and tumor necrosis factor-alpha in mouse endothelial cells.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Differential regulation of gamma-glutamylcysteine synthetase heavy and light subunit gene expression

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Tumor necrosis factor increases hepatocellular glutathione by transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Identification of glutathione S-transferase isozymes and gamma-glutamylcysteine synthetase as negative acute-phase proteins in rat liver

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Glutathione regulation in rat hepatic stellate cells. Comparative studies in primary culture and in liver injury in vivo

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Posttranscriptional regulation of MRP/GS-X pump and gamma-glutamylcysteine synthetase expression by 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea and by cycloheximide in human glioma cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Expression of multidrug resistance protein/GS-X pump and gamma-glutamylcysteine synthetase genes is regulated by oxidative stress.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Induction of antioxidants by adriamycin in mouse heart

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Nitric oxide-dependent induction of glutathione synthesis through increased expression of gamma-glutamylcysteine synthetase

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Interleukin-1-induced nitric oxide production modulates glutathione synthesis in cultured rat hepatocytes

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Transforming growth factor-beta1 is a potent inhibitor of glutathione synthesis in the lung epithelial cell line A549: transcriptional effect on the GSH rate-limiting enzyme gamma-glutamylcysteine synthetase

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Induction of mRNAs for glutathione synthesis-related proteins in mouse liver by low doses of gamma-rays

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Transcriptional regulation of the heavy subunit chain of gamma-glutamylcysteine synthetase by ionizing radiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Localization of glutathione and induction of glutathione synthesis-related proteins in mouse brain by low doses of gamma-rays

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Alteration of transcriptional and post-transcriptional expression of gamma-glutamylcysteine synthetase by diethyl maleate.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Induction of gamma-glutamylcysteine synthetase by prostaglandin A2 in L-1210 cells

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Specific role of an alpha,beta-unsaturated carbonyl group in gamma-glutamylcysteine synthetase induction by prostaglandin A2.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Insulin and glucocorticoid dependence of hepatic gamma-glutamylcysteine synthetase and glutathione synthesis in the rat. Studies in cultured hepatocytes and in vivo

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Weakened cellular scavenging activity against oxidative stress in diabetes mellitus: regulation of glutathione synthesis and efflux

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Up-regulation of glutathione synthesis in rat kidney by methyl mercury. Relationship to mercury-induced oxidative stress

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Effect of selenium on glutathione metabolism. Induction of gamma-glutamylcysteine synthetase and glutathione reductase in the rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Coordinated induction of MRP/GS-X pump and gamma-glutamylcysteine synthetase by heavy metals in human leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Influence of selenium on glutathione and some associated enzymes in rats with mammary tumor induced by 7,12-dimethylbenz(a)anthracene

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Modulation of gamma-glutamylcysteine synthetase large subunit mRNA expression by butylated hydroxyanisole.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Regulation of [Ah] gene battery enzymes and glutathione levels by 5,10-dihydroindeno[1,2-b]indole in mouse hepatoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

An electrophile responsive element (EpRE) regulates beta-naphthoflavone induction of the human gamma-glutamylcysteine synthetase regulatory subunit gene. Constitutive expression is mediated by an adjacent AP-1 site

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Studies on the regulation of glutathione level in rat liver

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Role of membrane transport in metabolism and function of glutathione in mammals

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Changes in levels of glutathione and related compounds and activities of glutathione-related enzymes during rat liver regeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Expression and characterization of human glutamate-cysteine ligase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Glutathione: interorgan translocation, turnover, and metabolism

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Rat Liver Glutathione: Possible Role as a Reservoir of Cysteine

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

A novel physiological role of liver glutathione as a reservoir of L-cysteine

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7 January 2021

Glutathione therapy: from prodrugs to genes

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Increased uptake of L-cysteine and L-cystine by nerve growth factor in rat pheochromocytoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Expression of gamma-glutamyl transpeptidase provides tumor cells with a selective growth advantage at physiologic concentrations of cyst(e)ine

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Clinical studies of reversal of drug resistance based on glutathione

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Glutathione and related enzymes in multidrug resistance

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Plasma glutamate concentration and lymphocyte activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Low concentrations of acid-soluble thiol (cysteine) in the blood plasma of HIV-1-infected patients.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Effects of ATP level on glutathione regeneration in rabbit and guinea-pig erythrocytes

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Vulnerability to glucose deprivation injury correlates with glutathione levels in astrocytes.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Alpha-adrenergic modulation of glutathione metabolism in isolated rat hepatocytes

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Hormone-mediated down-regulation of hepatic glutathione synthesis in the rat

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Regulation of gamma-glutamylcysteine synthetase by protein phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Regulation of hepatocyte glutathione by amino acid precursors and cAMP in protein-energy malnourished rats

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Time course for the elevation of glutathione in numerous organs of L1210-bearing CDF1 mice given the l-cysteine prodrug, RibCys

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Intracellular cysteine delivery system that protects against toxicity by promoting glutathione synthesis

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Transport of glutathione diethyl ester into human cells

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Chemical depletion of glutathione in vivo

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Origin and turnover of mitochondrial glutathione

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Analytical and preparative separation of the diastereomers of l-buthionine (SR)-sulfoximine, a potent inhibitor of glutathione biosynthesis

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https://api.crossref.org/works/10.1016%2FS0891-5849%2899%2900176-8

7 January 2021

Design, synthesis and evaluation of transition-state analogue inhibitors of Escherichia coli gamma-glutamylcysteine synthetase

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7 January 2021

Hammerhead ribozymes against gamma-glutamylcysteine synthetase mRNA down-regulate intracellular glutathione concentration of mouse islet cells

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7 January 2021

10.1016/S0891-5849(99)00176-8

Identifiers

DOI

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29 July 2017

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