Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance (Q33784453)

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English	Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

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Europe PubMed Central

Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance (English)

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Europe PubMed Central

PubMed publication ID

29 July 2017

multiple drug resistance

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based on heuristic

inferred from title

author name string

J König

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

A T Nies

2

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

Y Cui

3

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

I Leier

4

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

D Keppler

5

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

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publication date

1 December 1999

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Europe PubMed Central

PubMed publication ID

29 July 2017

number of pages

18

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based on heuristic

inferred from page(s)

Biochimica et Biophysica Acta

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Europe PubMed Central

PubMed publication ID

29 July 2017

1461

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Europe PubMed Central

PubMed publication ID

29 July 2017

2

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Europe PubMed Central

PubMed publication ID

29 July 2017

377-394

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Europe PubMed Central

PubMed publication ID

29 July 2017

Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

1 reference

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7 January 2021

ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids

1 reference

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7 January 2021

Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3).

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Functional analysis of a canalicular multispecific organic anion transporter cloned from rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

The GS-X Pump in Plant, Yeast, and Animal Cells: Structure, Function, and Gene Expression

1 reference

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7 January 2021

FROM VACUOLAR GS-X PUMPS TO MULTISPECIFIC ABC TRANSPORTERS.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Transport function and substrate specificity of multidrug resistance protein

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

ATP-dependent efflux of calcein by the multidrug resistance protein (MRP): no inhibition by intracellular glutathione depletion.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Transport properties of the multidrug resistance-associated protein (MRP) in human tumour cells

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Expression of the apical conjugate export pump, Mrp2, in the polarized hepatoma cell line, WIF-B.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

A multidrug-resistance protein (MRP)-like transmembrane pump is highly expressed by resting murine T helper (Th) 2, but not Th1 cells, and is induced to equal expression levels in Th1 and Th2 cells after antigenic stimulation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Export pumps for anionic conjugates encoded by MRP genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Characterization of the ATP-dependent leukotriene C4 export carrier in mastocytoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Glutathione transport by inside-out vesicles from human erythrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Glutathione S-conjugate transport using inside-out vesicles from human erythrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

ATP stimulates the uptake of S-dinitrophenylglutathione by rat liver plasma membrane vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

ATP-stimulated uptake of S-(2,4-dinitrophenyl)glutathione by plasma membrane vesicles from rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

ATP-dependent leukotriene export from mastocytoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Hereditary defect of hepatobiliary cysteinyl leukotriene elimination in mutant rats with defective hepatic anion excretion

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

MRP3, an organic anion transporter able to transport anti-cancer drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

X-HUSAR, an X-based graphical interface for the analysis of genomic sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

A comprehensive set of sequence analysis programs for the VAX

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Merck Frosst Award Lecture 1998. Molecular dissection of the human multidrug resistance P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Membrane topology distinguishes a subfamily of the ATP-binding cassette (ABC) transporters

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Analysis of the intron-exon organization of the human multidrug-resistance protein gene (MRP) and alternative splicing of its mRNA

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Exon-intron organization of the human multidrug-resistance protein 2 (MRP2) gene mutated in Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Membrane topology and glycosylation of the human multidrug resistance-associated protein

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Topology mapping of the amino-terminal half of multidrug resistance-associated protein by epitope insertion and immunofluorescence

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Epitope insertion favors a six transmembrane domain model for the carboxy-terminal portion of the multidrug resistance-associated protein

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Prediction of transmembrane segments in proteins utilising multiple sequence alignments

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Human MRP3 transporter: identification of the 5′-flanking region, genomic organization and alternative splice variants1The GenBank accession numbers of MRP3 and its splice variants MRP3A and MRP3B described in this paper are AF085690, AF085691 and

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

The anthracycline resistance-associated (ara) gene, a novel gene associated with multidrug resistance in a human leukaemia cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

ATP-dependent transport of aflatoxin B1 and its glutathione conjugates by the product of the multidrug resistance protein (MRP) gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Transport of the glutathione conjugate of ethacrynic acid by the human multidrug resistance protein MRP

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Pharmacological characterization of the murine and human orthologs of multidrug-resistance protein in transfected human embryonic kidney cells

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Multidrug resistance protein-mediated transport of chlorambucil and melphalan conjugated to glutathione

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Functional multidrug resistance protein (MRP1) lacking the N-terminal transmembrane domain

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Transport of monoglucuronosyl and bisglucuronosyl bilirubin by recombinant human and rat multidrug resistance protein 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Defective ATP-dependent bile canalicular transport of organic anions in mutant (TR-) rats with conjugated hyperbilirubinemia

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Two distinct mechanisms for bilirubin glucuronide transport by rat bile canalicular membrane vesicles. Demonstration of defective ATP-dependent transport in rats (TR-) with inherited conjugated hyperbilirubinemia

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Hepatobiliary elimination of the peroxisome proliferator nafenopin by conjugation and subsequent ATP-dependent transport across the canalicular membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

A possible role of inwardly rectifying K+ channels in chick myoblast differentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Differential inhibition by cyclosporins of primary-active ATP-dependent transporters in the hepatocyte canalicular membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

The specific bisindolylmaleimide PKC-inhibitor GF 109203X efficiently modulates MRP-associated multiple drug resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Human canalicular multispecific organic anion transporter (cMOAT) is expressed in human lung, gastric, and colorectal cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Induction of the multispecific organic anion transporter (cMoat/mrp2) gene and biliary glutathione secretion by the herbicide 2,4,5-trichlorophenoxyacetic acid in the mouse liver

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Transport of the flavonoid chrysin and its conjugated metabolites by the human intestinal cell line Caco-2.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Different pattern of MRP localization in ciliated and basal cells from human bronchial epithelium

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

cDNA cloning and inducible expression of human multidrug resistance associated protein 3 (MRP3)

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Isolation of a novel human canalicular multispecific organic anion transporter, cMOAT2/MRP3, and its expression in cisplatin-resistant cancer cells with decreased ATP-dependent drug transport

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Osmodependent dynamic localization of the multidrug resistance protein 2 in the rat hepatocyte canalicular membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Green fluorescent protein: applications in cell biology

1 reference

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7 January 2021

The green fluorescent protein

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Increased levels of the multidrug resistance protein in lateral membranes of proliferating hepatocyte-derived cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Targeting of aminopeptidase N to bile canaliculi correlates with secretory activities of the developing canalicular domain

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Evidence for a multidrug resistance-associated protein 1 (MRP1)-related transport system in cultured rat liver biliary epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

WIF-B cells: an in vitro model for studies of hepatocyte polarity

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Mutations in the canilicular multispecific organic anion transporter (cMOAT) gene, a novel ABC transporter, in patients with hyperbilirubinemia II/Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Genomic structure of the canalicular multispecific organic anion-transporter gene (MRP2/cMOAT) and mutations in the ATP-binding-cassette region in Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

A splice mutation in the human canalicular multispecific organic anion transporter gene causes Dubin-Johnson syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Chronic idiopathic jaundice with unidentified pigment in liver cells; a new clinicopathologic entity with a report of 12 cases

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Persistent non-hemolytic hyperbilirubinemia associated with lipochrome-like pigment in liver cells: report of four cases

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Binary specification of nonsense codons by splicing and cytoplasmic translation

1 reference

https://api.crossref.org/works/10.1016%2FS0005-2736%2899%2900169-8

7 January 2021

Identifiers

10.1016/S0005-2736(99)00169-8

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

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