Dominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion protein (Q33803953)

29 July 2017

title

Dominant-negative inhibition of prion formation diminished by deletion mutagenesis of the prion protein (English)

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29 July 2017

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7

S B Prusiner

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29 July 2017

6

F E Cohen

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29 July 2017

L Zulianello

1

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29 July 2017

K Kaneko

2

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29 July 2017

M Scott

3

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29 July 2017

S Erpel

4

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29 July 2017

D Han

5

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29 July 2017

language of work or name

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1 May 2000

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29 July 2017

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29 July 2017

volume

74

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29 July 2017

issue

9

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29 July 2017

page(s)

4351-4360

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Prion protein of 106 residues creates an artifical transmission barrier for prion replication in transgenic mice

29 July 2017

cites work

1 reference

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Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication

4 July 2018

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Copper binding to the prion protein: structural implications of four identical cooperative binding sites

4 July 2018

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Eight prion strains have PrP(Sc) molecules with different conformations

4 July 2018

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4 July 2018

Prion Protein Biology

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Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions

4 July 2018

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Abnormal properties of prion protein with insertional mutations in different cell types

4 July 2018

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A transmembrane form of the prion protein in neurodegenerative disease

4 July 2018

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The cellular prion protein binds copper in vivo

4 July 2018

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The human 37-kDa laminin receptor precursor interacts with the prion protein in eukaryotic cells

4 July 2018

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Complementary hydropathy identifies a cellular prion protein receptor

4 July 2018

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Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible

4 July 2018

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Propagation of prion strains through specific conformers of the prion protein

4 July 2018

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Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform

4 July 2018

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Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation

4 July 2018

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Prion protein structure and scrapie replication: theoretical, spectroscopic, and genetic investigations

4 July 2018

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Identification of candidate proteins binding to prion protein

4 July 2018

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COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform

4 July 2018

1 reference

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Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform

4 July 2018

1 reference

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Recombinant scrapie-like prion protein of 106 amino acids is soluble

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains

4 July 2018

1 reference

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Evidence for the conformation of the pathologic isoform of the prion protein enciphering and propagating prion diversity

4 July 2018

1 reference

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Autonomous and reversible folding of a soluble amino-terminally truncated segment of the mouse prion protein.

4 July 2018

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NMR structure of the mouse prion protein domain PrP(121-231)

4 July 2018

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Prion protein PrPc interacts with molecular chaperones of the Hsp60 family

4 July 2018

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Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

A new variant of Creutzfeldt-Jakob disease in the UK.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Conversion of truncated and elongated prion proteins into the scrapie isoform in cultured cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Distinct PrP properties suggest the molecular basis of strain variation in transmissible mink encephalopathy.

4 July 2018

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Homozygosity for prion protein alleles encoding glutamine-171 renders sheep susceptible to natural scrapie

4 July 2018

1 reference

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Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice

4 July 2018

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Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins

4 July 2018

1 reference

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Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein

4 July 2018

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Glycolipid-anchored proteins in neuroblastoma cells form detergent-resistant complexes without caveolin

4 July 2018

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Purification and structural studies of a major scrapie prion protein

4 July 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

4 July 2018

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Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Changes in the localization of brain prion proteins during scrapie infection

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

The saga of IMAC and MIT.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Creutzfeldt-Jakob disease and scrapie prions

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Expression of a constitutively activated mutant of the beta-isozyme of protein kinase C in cardiac myocytes stimulates the promoter of the beta-myosin heavy chain isogene.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Scrapie and cellular prion proteins differ in their kinetics of synthesis and topology in cultured cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Rapid detection of Creutzfeldt-Jakob disease and scrapie prion proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Epitope mapping of the Syrian hamster prion protein utilizing chimeric and mutant genes in a vaccinia virus expression system

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Lipofection of cDNAs in the embryonic vertebrate central nervous system

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Transmissible familial Creutzfeldt-Jakob disease associated with five, seven, and eight extra octapeptide coding repeats in the PRNP gene

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Molecular biology of prion diseases

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Purification and properties of the cellular prion protein from Syrian hamster brain

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Inherited prion disease with 144 base pair gene insertion. 1. Genealogical and molecular studies

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Chimeric prion protein expression in cultured cells and transgenic mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Pathologic conformations of prion proteins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Codon 219 Lys allele of PRNP is not found in sporadic Creutzfeldt-Jakob disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Prion protein selectively binds copper(II) ions

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

The cellular prion protein binds copper in vivo

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Identification of cellular proteins binding to the scrapie prion protein

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=111952

Association between natural scrapie and PrP genotype in a flock of Suffolk sheep in Scotland

30 October 2018

1 reference

12 December 2020

Transmissible and non-transmissible neurodegenerative disease: similarities in age of onset and genetics in relation to aetiology

1 reference

12 December 2020

Precise targeting of the pathology of the sialoglycoprotein, PrP, and vacuolar degeneration in mouse scrapie

1 reference

12 December 2020

The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive

1 reference

12 December 2020

Copper binding to the N-terminal tandem repeat region of mammalian and avian prion protein: structural studies using synthetic peptides

1 reference

12 December 2020

Is scrapie solely a genetic disease?

1 reference

12 December 2020

Protective prion protein polymorphisms against sporadic Creutzfeldt-Jakob disease

1 reference

12 December 2020

Deaths from variant Creutzfeldt-Jakob disease

1 reference

12 December 2020

10.1128/JVI.74.9.4351-4360.2000

Identifiers

DOI

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29 July 2017

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29 July 2017

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