Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes (Q33829075)

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English	Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

29 July 2017

Attachment of a 40-base-pair G + C-rich sequence (GC-clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes (English)

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

author name string

V C Sheffield

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

D R Cox

2

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Europe PubMed Central

PubMed publication ID

29 July 2017

L S Lerman

3

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Europe PubMed Central

PubMed publication ID

29 July 2017

R M Myers

4

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Europe PubMed Central

PubMed publication ID

29 July 2017

language of work or name

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publication date

1 January 1989

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Europe PubMed Central

PubMed publication ID

29 July 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

PubMed publication ID

29 July 2017

86

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Europe PubMed Central

PubMed publication ID

29 July 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

232-236

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Europe PubMed Central

PubMed publication ID

29 July 2017

describes a project that uses

polymerase chain reaction

1 reference

based on heuristic

inferred from title

Linkage of beta-thalassaemia mutations and beta-globin gene polymorphisms with DNA polymorphisms in human beta-globin gene cluster

1 reference

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Direct identification of sickle cell anemia by blot hybridization

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Construction of a genetic linkage map in man using restriction fragment length polymorphisms

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DNA fragments differing by single base-pair substitutions are separated in denaturing gradient gels: correspondence with melting theory

1 reference

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The mutation and polymorphism of the human beta-globin gene and its surrounding DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=286438

4 July 2018

Nearly all single base substitutions in DNA fragments joined to a GC-clamp can be detected by denaturing gradient gel electrophoresis

1 reference

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An improved method for prenatal diagnosis of genetic diseases by analysis of amplified DNA sequences. Application to hemophilia A.

1 reference

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Specific enzymatic amplification of DNA in vitro: the polymerase chain reaction

1 reference

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4 July 2018

Detection and localization of single base changes by denaturing gradient gel electrophoresis

1 reference

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4 July 2018

[21] Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction

1 reference

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Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia

1 reference

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A general method for saturation mutagenesis of cloned DNA fragments

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Isolation of probes detecting restriction fragment length polymorphisms from X chromosome-specific libraries: potential use for diagnosis of Duchenne muscular dystrophy

1 reference

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Modification of the melting properties of duplex DNA by attachment of a GC-rich DNA sequence as determined by denaturing gradient gel electrophoresis

1 reference

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Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase

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Analysis of the beta-delta-globin gene loci in normal and Hb Lepore DNA: direct determination of gene linkage and intergene distance

1 reference

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Length-independent separation of DNA restriction fragments in two-dimensional gel electrophoresis

1 reference

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Evolution of sickle variant gene

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Polymerase chain reaction reveals cloning artefacts

1 reference

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A Sensitive New Prenatal Test for Sickle-Cell Anemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/2643100

12 December 2020

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Improved detection of the sickle mutation by DNA analysis: application to prenatal diagnosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2643100

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based on heuristic

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Prenatal diagnosis of beta-thalassemia. Detection of a single nucleotide mutation in DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/2643100

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α1-Antitrypsin deficiency detection by direct analysis of the mutation in the gene

1 reference

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based on heuristic

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Detection of single base substitutions in total genomic DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/2643100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2643100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid prenatal diagnosis of sickle cell anemia by a new method of DNA analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2643100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recent advances in the development of methods for detecting single-base substitutions associated with human genetic diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/2643100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Searching for gene defects by denaturing gradient gel electrophoresis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2643100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Computational simulation of DNA melting and its application to denaturing gradient gel electrophoresis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2643100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/2643100

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.86.1.232

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

1989PNAS...86..232S

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

29 July 2017

ResearchGate publication ID

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