Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis (Q33890912)

29 July 2017

title

Two elements target SIV Nef to the AP-2 clathrin adaptor complex, but only one is required for the induction of CD4 endocytosis (English)

1 reference

29 July 2017

T Swigut

4

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author name string

M Lock

1

1 reference

29 July 2017

M E Greenberg

2

1 reference

29 July 2017

A J Iafrate

3

1 reference

29 July 2017

J Muench

5

1 reference

29 July 2017

F Kirchhoff

6

1 reference

29 July 2017

N Shohdy

7

1 reference

29 July 2017

J Skowronski

8

1 reference

29 July 2017

language of work or name

English

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publication date

1 May 1999

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29 July 2017

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29 July 2017

volume

18

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29 July 2017

issue

10

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29 July 2017

page(s)

2722-2733

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A structural explanation for the recognition of tyrosine-based endocytotic signals

29 July 2017

cites work

1 reference

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A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4

5 July 2018

1 reference

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A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor

5 July 2018

1 reference

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HIV-1: fifteen proteins and an RNA

5 July 2018

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Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity

5 July 2018

1 reference

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5 July 2018

Nef--an adaptor adaptor?

1 reference

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HIV-1 regulatory/accessory genes: keys to unraveling viral and host cell biology

5 July 2018

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Interactions between HIV1 Nef and vacuolar ATPase facilitate the internalization of CD4

5 July 2018

1 reference

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Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules

5 July 2018

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The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes

5 July 2018

1 reference

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Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes

5 July 2018

1 reference

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Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site

5 July 2018

1 reference

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5 July 2018

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Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation

5 July 2018

1 reference

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Human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus Nef use distinct but overlapping target sites for downregulation of cell surface CD4.

5 July 2018

1 reference

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Linking cargo to vesicle formation: receptor tail interactions with coat proteins.

5 July 2018

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Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques

5 July 2018

1 reference

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Clathrin-coated vesicle formation and protein sorting: an integrated process

5 July 2018

1 reference

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The nef gene products of both simian and human immunodeficiency viruses enhance virus infectivity and are functionally interchangeable.

5 July 2018

1 reference

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Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling

5 July 2018

1 reference

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Construction, replication, and immunogenic properties of a simian immunodeficiency virus expressing interleukin-2.

5 July 2018

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Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes

5 July 2018

1 reference

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Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

Endocytic and exocytic regulation of CD4 expression and function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type 1-infected individuals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sorting

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

The human immunodeficiency virus-1 nef gene product: a positive factor for viral infection and replication in primary lymphocytes and macrophages

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection

5 July 2018

1 reference

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Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

The importance of nef in the induction of human immunodeficiency virus type 1 replication from primary quiescent CD4 lymphocytes.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

Characterization of a CD4-expressing macaque cell line that can detect virus after a single replication cycle and can be infected by diverse simian immunodeficiency virus isolates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

Identification of a protein kinase as an intrinsic component of rat liver coated vesicles.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

Structural relationships between clathrin assembly proteins from the Golgi and the plasma membrane

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

Differential transcriptional activation by Oct-1 and Oct-2: interdependent activation domains induce Oct-2 phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

Use of T7 RNA polymerase to direct expression of cloned genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

Stabilization of clathrin coats by the core of the clathrin-associated protein complex AP-2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

Serine phosphorylation-independent downregulation of cell-surface CD4 by nef

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

Protein sorting by tyrosine-based signals: adapting to the Ys and wherefores

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171354

Improved high-level expression system for eukaryotic genes in Escherichia coli using T7 RNA polymerase and rare ArgtRNAs

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10329619

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/EMBOJ/18.10.2722

1 reference

29 July 2017

1 reference

29 July 2017

1 reference