The Alzheimer's disease mitochondrial cascade hypothesis (Q33905871)

29 July 2017

1 reference

title

The Alzheimer's disease mitochondrial cascade hypothesis (English)

1 reference

29 July 2017

0 references

Russell H Swerdlow

1

1 reference

29 July 2017

Jeffrey M Burns

series ordinal

2

1 reference

29 July 2017

Shaharyar M Khan

series ordinal

3

1 reference

29 July 2017

publication date

1 January 2010

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Journal of Alzheimer's Disease

29 July 2017

published in

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29 July 2017

volume

20 Suppl 2

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29 July 2017

page(s)

S265-79

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Creative Commons Attribution-NonCommercial 4.0 International

29 July 2017

copyright license

start time

3 June 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease

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Association of parental dementia with cognitive and brain MRI measures in middle-aged adults

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A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease

5 July 2018

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5 July 2018

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Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle

5 July 2018

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Regulation of neuron mitochondrial biogenesis and relevance to brain health

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Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease

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Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial

5 July 2018

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Bone density and brain atrophy in early Alzheimer's disease

5 July 2018

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Body mass index and cognitive decline in mild cognitive impairment

5 July 2018

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APOE mRNA and protein expression in postmortem brain are modulated by an extended haplotype structure

5 July 2018

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The Alzheimer's disease mitochondrial cascade hypothesis: an update

5 July 2018

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Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model

5 July 2018

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A specific enzyme-linked immunosorbent assay for measuring beta-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease

5 July 2018

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Declining brain glucose metabolism in normal individuals with a maternal history of Alzheimer disease

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Amyloid-beta dynamics correlate with neurological status in the injured human brain

5 July 2018

1 reference

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Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Cardiorespiratory fitness and brain atrophy in early Alzheimer disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels.

5 July 2018

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Pathogenesis of Alzheimer's disease

5 July 2018

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Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism

5 July 2018

1 reference

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Amyloid precursor protein and mitochondrial dysfunction in Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Cytochrome c oxidase deficiency in neurons decreases both oxidative stress and amyloid formation in a mouse model of Alzheimer's disease

5 July 2018

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Treating neurodegeneration by modifying mitochondria: potential solutions to a "complex" problem

5 July 2018

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Comprehensive analysis of APOE and selected proximate markers for late-onset Alzheimer's disease: patterns of linkage disequilibrium and disease/marker association

5 July 2018

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The thiazolidinedione pioglitazone alters mitochondrial function in human neuron-like cells

5 July 2018

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A beta oligomers - a decade of discovery

5 July 2018

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Mitochondria in cybrids containing mtDNA from persons with mitochondriopathies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Impaired platelet mitochondrial activity in Alzheimer's disease and mild cognitive impairment

5 July 2018

1 reference

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Amyloid imaging of Alzheimer's disease using Pittsburgh Compound B.

5 July 2018

1 reference

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The mitochondrial energy transduction system and the aging process

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Cell and animal models of mtDNA biology: progress and prospects

5 July 2018

1 reference

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Is aging part of Alzheimer's disease, or is Alzheimer's disease part of aging?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Clinical effects of Abeta immunization (AN1792) in patients with AD in an interrupted trial.

5 July 2018

1 reference

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Mitochondria-derived oxidative stress induces a heat shock protein response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Premature ageing in mice expressing defective mitochondrial DNA polymerase

5 July 2018

1 reference

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Alzheimer's disease: the two-hit hypothesis

5 July 2018

1 reference

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Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Mitochondria in Alzheimer's disease

5 July 2018

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Tauists, Baptists, Syners, Apostates, and new data

5 July 2018

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

5 July 2018

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Does insulin dysfunction play a role in Alzheimer's disease?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Apolipoprotein E and Alzheimer's disease: signal transduction mechanisms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Alzheimer's disease cybrids replicate beta-amyloid abnormalities through cell death pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans

5 July 2018

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Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

The incidence of dementia: a meta-analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Mitochondrial function impairment induced by amyloid beta-peptide on PC12 cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Elevated levels of the Kearns-Sayre syndrome mitochondrial DNA deletion in temporal cortex of Alzheimer's patients

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Cybrids in Alzheimer's disease: a cellular model of the disease?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Effect of energy shortage and oxidative stress on amyloid precursor protein metabolism in COS cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Calcium homeostasis and reactive oxygen species production in cells transformed by mitochondria from individuals with sporadic Alzheimer's disease.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Factors associated with survival to 75 years of age in middle-aged men and women. The Framingham Study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Oxidative damage and mitochondrial decay in aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Candidate gene for the chromosome 1 familial Alzheimer's disease locus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Reduced Activities of Thiamine-Dependent Enzymes in the Brains and Peripheral Tissues of Patients With Alzheimer's Disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Hypotheses concerning the aetiology of Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Linkage studies in familial Alzheimer disease: evidence for chromosome 19 linkage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Family patterns of coronary heart disease mortality: the Framingham Longevity Study

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Alzheimer's disease: the amyloid cascade hypothesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Ultrastructural localization of Alzheimer amyloid beta/A4 protein precursor in the cytoplasm of neurons and senile plaque-associated astrocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Editorial: The prevalence and malignancy of Alzheimer disease. A major killer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Homotaurine: a failed drug for Alzheimer's disease and now a nutraceutical for memory protection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Age, neuropathology, and dementia

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Genetic association study on in and around the APOE in late-onset Alzheimer disease in Japanese.

29 October 2018

1 reference

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If we live long enough, will we all be demented?: redux

29 October 2018

1 reference

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Prevalence of dementia after age 90: results from the 90+ study.

29 October 2018

1 reference

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Cardiorespiratory fitness in early-stage Alzheimer disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Peripheral insulin and brain structure in early Alzheimer disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Incident dementia in women is preceded by weight loss by at least a decade

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Annonacin, a natural mitochondrial complex I inhibitor, causes tau pathology in cultured neurons

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

PET amyloid ligand [11C]PIB uptake is increased in mild cognitive impairment

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Rosiglitazone induces mitochondrial biogenesis in mouse brain.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Accelerated weight loss may precede diagnosis in Alzheimer disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

The mitochondrial complex I inhibitor rotenone triggers a cerebral tauopathy

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Change in body mass index and risk of incident Alzheimer disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

A 32-year prospective study of change in body weight and incident dementia: the Honolulu-Asia Aging Study

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

A chronic Alzheimer's model evoked by mitochondrial poison sodium azide for pharmacological investigations

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Analysis of European mitochondrial haplogroups with Alzheimer disease risk

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Oxidative stress increases expression and activity of BACE in NT2 neurons

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Functional mitochondria are required for amyloid beta-mediated neurotoxicity

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Correlation of the clinical severity of Alzheimer's disease with an aberration in mitochondrial DNA (mtDNA).

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Mitochondrial abnormalities in Alzheimer's disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Mitochondrial DNA damage as a mechanism of cell loss in Alzheimer's disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

beta-Amyloid fragment 25-35 selectively decreases complex IV activity in isolated mitochondria

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Weight change in Alzheimer's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

A comparison of familial and sporadic Alzheimer's disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Alzheimer's disease and transmissible virus dementia (Creutzfeldt-Jakob disease).

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Coenzyme a-acetylating enzymes in Alzheimer's disease: Possible cholinergic ‘compartment’ of pyruvate dehydrogenase

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Brain Cytochrome Oxidase in Alzheimer's Disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

The Outcome of Elderly Patients with Cognitive Complaints but Normal Neuropsychological Tests

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2883665

Cytochrome oxidase deficiency in Alzheimer's disease

29 October 2018

1 reference

12 December 2020

Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative

1 reference

12 December 2020

Increased risk of dementia in mothers of Alzheimer's disease cases: evidence for maternal inheritance

1 reference

12 December 2020

Marked changes in mitochondrial DNA deletion levels in Alzheimer brains

1 reference

12 December 2020

1 reference

12 December 2020

Weight loss precedes dementia in community-dwelling older adults

1 reference

12 December 2020

Regulation of alzheimer beta-amyloid precursor trafficking and metabolism

1 reference

12 December 2020

The transmembrane aspartates in presenilin 1 and 2 are obligatory for gamma-secretase activity and amyloid beta-protein generation

1 reference

12 December 2020

Stimulation of "stress-regulated" mitogen-activated protein kinases (stress-activated protein kinases/c-Jun N-terminal kinases and p38-mitogen-activated protein kinases) in perfused rat hearts by oxidative and other stresses

1 reference

12 December 2020

Identifiers

DOI

10.3233/JAD-2010-100339

1 reference

29 July 2017

1 reference

29 July 2017

1 reference