Partial impairment of cytokine responses in Tyk2-deficient mice (Q33924660)

30 July 2017

title

Partial impairment of cytokine responses in Tyk2-deficient mice (English)

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ORCID Public Data File 2021

30 July 2017

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Mathias Müller

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ORCID Public Data File 2021

author name string

Karaghiosoff M

1

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30 July 2017

Neubauer H

2

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30 July 2017

Lassnig C

3

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30 July 2017

Kovarik P

4

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30 July 2017

Schindler H

5

1 reference

30 July 2017

Pircher H

6

1 reference

30 July 2017

McCoy B

7

1 reference

30 July 2017

Bogdan C

8

1 reference

30 July 2017

Decker T

9

1 reference

30 July 2017

Brem G

10

1 reference

30 July 2017

Pfeffer K

11

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30 July 2017

Müller M

12

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30 July 2017

language of work or name

English

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publication date

1 October 2000

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30 July 2017

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30 July 2017

volume

13

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30 July 2017

issue

4

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30 July 2017

page(s)

549-560

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Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12

30 July 2017

cites work

1 reference

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7 January 2021

Inducible nitric-oxide synthase plays a minimal role in lymphocytic choriomeningitis virus-induced, T cell-mediated protective immunity and immunopathology

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7 January 2021

Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity

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7 January 2021

JAKs and STATs branch out.

1 reference

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7 January 2021

Direct binding to and tyrosine phosphorylation of the alpha subunit of the type I interferon receptor by p135tyk2 tyrosine kinase

1 reference

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7 January 2021

Two roads diverged: interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection

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7 January 2021

STATs and gene regulation

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7 January 2021

Impaired antiviral response and alpha/beta interferon induction in mice lacking beta interferon.

1 reference

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7 January 2021

Thrombopoietin signal transduction requires functional JAK2, not TYK2

1 reference

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7 January 2021

An interferon-gamma-activated site (GAS) is necessary for full expression of the mouse iNOS gene in response to interferon-gamma and lipopolysaccharide

1 reference

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7 January 2021

A major role for the protein tyrosine kinase JAK1 in the JAK/STAT signal transduction pathway in response to interleukin-6.

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7 January 2021

Cytokine receptor signalling

1 reference

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7 January 2021

Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4

1 reference

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7 January 2021

Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

1 reference

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7 January 2021

Inhibition of Viral Replication by Interferon-γ-Induced Nitric Oxide Synthase

1 reference

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7 January 2021

Possible involvement of Janus kinase Jak2 in interferon-gamma induction of nitric oxide synthase in rat glial cells

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7 January 2021

Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900054-6

7 January 2021

Stress-induced phosphorylation of STAT1 at Ser727 requires p38 mitogen-activated protein kinase whereas IFN-gamma uses a different signaling pathway

1 reference

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7 January 2021

Nitric oxide and macrophage function

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7 January 2021

IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses

1 reference

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7 January 2021

Activation of the transcription factor ISGF3 by interferon-gamma

1 reference

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7 January 2021

The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction

1 reference

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7 January 2021

Functional role of type I and type II interferons in antiviral defense

1 reference

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7 January 2021

Interleukin 3 activates not only JAK2 and STAT5, but also Tyk2, STAT1, and STAT3.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900054-6

7 January 2021

Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis

1 reference

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7 January 2021

Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox

1 reference

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7 January 2021

Defective lymphoid development in mice lacking Jak3

1 reference

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7 January 2021

Jak2 is essential for signaling through a variety of cytokine receptors

1 reference

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7 January 2021

Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.

1 reference

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7 January 2021

The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs).

1 reference

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7 January 2021

The interferon gamma (IFN-gamma) receptor: a paradigm for the multichain cytokine receptor

1 reference

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7 January 2021

Compartmental differences in NK cell responsiveness to IL-12 during lymphocytic choriomeningitis virus infection

1 reference

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7 January 2021

Catalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900054-6

7 January 2021

Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900054-6

7 January 2021

Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900054-6

7 January 2021

Nitric oxide production is increased during murine vaccinia virus infection, but may not be essential for virus clearance

1 reference

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7 January 2021

Cytokines and JAK-STAT signaling

1 reference

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7 January 2021

Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components

1 reference

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7 January 2021

How cells respond to interferons

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7 January 2021

Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains

1 reference

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7 January 2021

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

1 reference

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7 January 2021

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

1 reference

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7 January 2021

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900054-6

7 January 2021

Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3

1 reference

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7 January 2021

Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity

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7 January 2021

Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors

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7 January 2021

IL-4 and IL-10 antagonize IL-12-mediated protection against acute vaccinia virus infection with a limited role of IFN-gamma and nitric oxide synthetase 2.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900054-6

7 January 2021

A protein tyrosine kinase in the interferon alpha/beta signaling pathway

1 reference

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7 January 2021

Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-gamma signal transduction pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900054-6

7 January 2021

STAT3 complements defects in an interferon-resistant cell line: evidence for an essential role for STAT3 in interferon signaling and biological activities

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900054-6

7 January 2021

The Janus kinase family of protein tyrosine kinases and their role in signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900054-6

7 January 2021

Visualization, characterization, and turnover of CD8+ memory T cells in virus-infected hosts

1 reference

https://api.crossref.org/works/10.1016%2FS1074-7613%2800%2900054-6

7 January 2021

10.1016/S1074-7613(00)00054-6

Identifiers

DOI

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30 July 2017

1 reference