Functional domains of the BRCA1 and BRCA2 proteins (Q33923811)

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English	Functional domains of the BRCA1 and BRCA2 proteins	scientific article

Statements

instance of

scholarly article

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stated in

Europe PubMed Central

PubMed publication ID

10819534

retrieved

30 July 2017

review article

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Europe PubMed Central

title

Functional domains of the BRCA1 and BRCA2 proteins (English)

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Europe PubMed Central

PubMed publication ID

10819534

retrieved

30 July 2017

author name string

Baer R

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

10819534

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30 July 2017

Lee WH

series ordinal

2

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stated in

Europe PubMed Central

PubMed publication ID

10819534

retrieved

30 July 2017

language of work or name

English

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inferred from title

publication date

1 October 1998

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Europe PubMed Central

PubMed publication ID

10819534

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30 July 2017

published in

Journal of Mammary Gland Biology and Neoplasia

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Europe PubMed Central

PubMed publication ID

10819534

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30 July 2017

volume

3

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stated in

Europe PubMed Central

PubMed publication ID

10819534

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30 July 2017

issue

4

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stated in

Europe PubMed Central

PubMed publication ID

10819534

retrieved

30 July 2017

page(s)

403-412

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Europe PubMed Central

PubMed publication ID

10819534

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30 July 2017

cites work

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel cytoplasmic protein that specifically binds to nuclear localization signal motifs

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

S phase specific formation of the human Rad51 protein nuclear foci in lymphocytes

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle regulation of BRCA1 messenger RNA in human breast epithelial cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle-dependent colocalization of BARD1 and BRCA1 proteins in discrete nuclear domains

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The BRC repeats are conserved in mammalian BRCA2 proteins

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Germline BRCA2 gene mutations in patients with apparently sporadic pancreatic carcinomas

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRCA1 is a component of the RNA polymerase II holoenzyme

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of phosphorylation on BRCA1 during the cell cycle and after DNA damage

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional activation by BRCA1

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure of the C3HC4 domain by 1H-nuclear magnetic resonance spectroscopy. A new structural class of zinc-finger

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic Changes of BRCA1 Subnuclear Location and Phosphorylation State Are Initiated by DNA Damage

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localization of BRCA1 and a splice variant identifies the nuclear localization signal

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine Brca2: sequence, map position, and expression pattern

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning, chromosomal mapping and expression pattern of the mouse Brca2 gene

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low incidence of BRCA2 mutations in breast carcinoma and other cancers

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRCA1 is a 220-kDa nuclear phosphoprotein that is expressed and phosphorylated in a cell cycle-dependent manner

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein partners of the BRCA1 tumor suppressor

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-delta11b

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRCA1 regulates p53-dependent gene expression

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathology of familial breast cancer: differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases. Breast Cancer Linkage Consortium

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle control of BRCA2

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does this have a familiar RING?

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the rat and mouse homologues of the BRCA2 breast cancer susceptibility gene

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a RING protein that can interact in vivo with the BRCA1 gene product

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical impact of detection of loss of heterozygosity of BRCA1 and BRCA2 markers in sporadic breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRCA1 is a cell cycle-regulated nuclear phosphoprotein

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequential Metal Binding by the RING Finger Domain of BRCA1†

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear location and cell cycle regulation of the BRCA2 protein

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Germ line mutation at BRCA1 affects the histoprognostic grade in hereditary breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRCA1 protein products ... Functional motifs...

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of BRCA1 with Rad51 in mitotic and meiotic cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linkage of early-onset familial breast cancer to chromosome 17q21

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BRCA1 expression is induced before DNA synthesis in both normal and tumor-derived breast cells.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple possible sites of BRCA2 interacting with DNA repair protein RAD51

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brca2 is coordinately regulated with Brca1 during proliferation and differentiation in mammary epithelial cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brca2 is required for embryonic cellular proliferation in the mouse

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional activation functions in BRCA2

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a transcriptional activation function of BRCA1 C-terminal region

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/10819534

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1023/A:1018736115722

1 reference

stated in

Europe PubMed Central

PubMed publication ID

10819534

retrieved

30 July 2017

Dimensions Publication ID

1024925887

0 references

PubMed publication ID

10819534

1 reference

stated in

Europe PubMed Central

PubMed publication ID

10819534

retrieved

30 July 2017

 

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