Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice (Q33931582)

30 July 2017

title

Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice (English)

1 reference

30 July 2017

main subject

photoreceptor protein

0 references

7

Krzysztof Palczewski

1 reference

30 July 2017

3

Marcin Golczak

1 reference

30 July 2017

1

Akiko Maeda

1 reference

30 July 2017

2

Tadao Maeda

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30 July 2017

4

Yoshikazu Imanishi

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30 July 2017

Patrick Leahy

5

1 reference

30 July 2017

Ryo Kubota

series ordinal

6

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30 July 2017

publication date

12 July 2006

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30 July 2017

published in

Molecular Pharmacology

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30 July 2017

volume

70

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30 July 2017

issue

4

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30 July 2017

page(s)

1220-1229

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G protein-coupled receptor rhodopsin

30 July 2017

cites work

1 reference

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Reductions in Serum Vitamin A Arrest Accumulation of Toxic Retinal Fluorophores: A Potential Therapy for Treatment of Lipofuscin-Based Retinal Diseases

5 July 2018

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5 July 2018

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Lecithin:retinol acyltransferase is responsible for amidation of retinylamine, a potent inhibitor of the retinoid cycle

5 July 2018

1 reference

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Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle.

5 July 2018

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RPE65 is the isomerohydrolase in the retinoid visual cycle

5 July 2018

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Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium

5 July 2018

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Positively charged retinoids are potent and selective inhibitors of the trans-cis isomerization in the retinoid (visual) cycle

5 July 2018

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Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Light exposure stimulates formation of A2E oxiranes in a mouse model of Stargardt's macular degeneration

5 July 2018

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5 July 2018

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Evaluation of the role of the retinal G protein-coupled receptor (RGR) in the vertebrate retina in vivo

5 July 2018

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Treatment with isotretinoin inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration

5 July 2018

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Massive light-driven translocation of transducin between the two major compartments of rod cells: a novel mechanism of light adaptation

5 July 2018

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Delayed dark-adaptation and lipofuscin accumulation in abcr+/- mice: implications for involvement of ABCR in age-related macular degeneration

5 July 2018

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5 July 2018

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Inhibition of the visual cycle in vivo by 13-cis retinoic acid protects from light damage and provides a mechanism for night blindness in isotretinoin therapy.

5 July 2018

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Rapid restoration of visual pigment and function with oral retinoid in a mouse model of childhood blindness

5 July 2018

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Biosynthesis of a major lipofuscin fluorophore in mice and humans with ABCR-mediated retinal and macular degeneration

5 July 2018

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Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice

5 July 2018

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Isolation and one-step preparation of A2E and iso-A2E, fluorophores from human retinal pigment epithelium

5 July 2018

1 reference

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A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy

5 July 2018

1 reference

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5 July 2018

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N-retinylidene-phosphatidylethanolamine is the preferred retinoid substrate for the photoreceptor-specific ABC transporter ABCA4 (ABCR).

5 July 2018

1 reference

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Isotretinoin treatment inhibits lipofuscin accumulation in a mouse model of recessive Stargardt's macular degeneration

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106413

Light-Dependent Translocation of Arrestin in the Absence of Rhodopsin Phosphorylation and Transducin Signaling

29 October 2018

1 reference

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The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106413

Kinetics of visual pigment regeneration in excised mouse eyes and in mice with a targeted disruption of the gene encoding interphotoreceptor retinoid-binding protein or arrestin.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106413

Light history and age-related changes in retinal light damage

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106413

29 October 2018

1 reference

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Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4106413

Regeneration of rhodopsin and isorhodopsin in rod outer segment preparations: absence of effect of solvent parameters

29 October 2018

1 reference

12 December 2020

Dependency of apparent relative quantum yield of isorhodopsin to rhodopsin on the photon density of picosecond laser pulse

1 reference

12 December 2020

Overexpression of Bcl-2 or Bcl-XL transgenes and photoreceptor degeneration

1 reference

12 December 2020

Arrestin translocation is induced at a critical threshold of visual signaling and is superstoichiometric to bleached rhodopsin

1 reference

12 December 2020

The mouse ERG before and after light damage is independent of p53

1 reference

12 December 2020

Identifiers

DOI

10.1124/MOL.106.026823

1 reference

30 July 2017

1 reference

30 July 2017

1 reference