Expression of the autoimmune susceptibility gene FcRL3 on human regulatory T cells is associated with dysfunction and high levels of programmed cell death-1. (Q33951920)

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English	Expression of the autoimmune susceptibility gene FcRL3 on human regulatory T cells is associated with dysfunction and high levels of programmed cell death-1.	scientific article

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19 January 2020

Expression of the autoimmune susceptibility gene FcRL3 on human regulatory T cells is associated with dysfunction and high levels of programmed cell death-1 (English)

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19 January 2020

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19 January 2020

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Louise A Swainson

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19 January 2020

Urmila D Bajpai

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19 January 2020

Joseph M McCune

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19 January 2020

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26 February 2010

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19 January 2020

Journal of Immunology

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19 January 2020

184

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19 January 2020

7

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19 January 2020

3639-3647

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19 January 2020

The FCRL3-169CT promoter single-nucleotide polymorphism, which is associated with systemic lupus erythematosus in a Japanese population, predicts expression of receptor protein on CD19+ B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

FCRL3, an autoimmune susceptibility gene, has inhibitory potential on B-cell receptor-mediated signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Association between Fc receptor-like 3 C169T polymorphism and risk of systemic lupus erythematosus: a meta-analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Fc receptor-like 3 protein expressed on IL-2 nonresponsive subset of human regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Mechanisms of foxp3+ T regulatory cell-mediated suppression

1 reference

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5 July 2018

PD-1 tempers Tregs in chronic HCV infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Critical loss of the balance between Th17 and T regulatory cell populations in pathogenic SIV infection

1 reference

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5 July 2018

Maternal alloantigens promote the development of tolerogenic fetal regulatory T cells in utero

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

CTLA-4 control over Foxp3+ regulatory T cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Telomerase activity of HIV-1-specific CD8+ T cells: constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

How regulatory T cells work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Regulatory T cells and immune tolerance

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Activation drives PD-1 expression during vaccine-specific proliferation and following lentiviral infection in macaques

1 reference

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5 July 2018

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Suppression of SIV-specific CD4+ T cells by infant but not adult macaque regulatory T cells: implications for SIV disease progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Fc receptor-like 5 inhibits B cell activation via SHP-1 tyrosine phosphatase recruitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Is FCRL3 a new general autoimmunity gene?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Epistatic interaction between FCRL3 and MHC in Spanish patients with IBD.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Thymic development and peripheral homeostasis of regulatory T cells.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Fc receptor-like molecules

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

FCRL3 promoter 169 CC homozygosity is associated with susceptibility to rheumatoid arthritis in Dutch Caucasians

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Rheumatoid arthritis association with the FCRL3 -169C polymorphism is restricted to PTPN22 1858T-homozygous individuals in a Canadian population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Selective dysregulation of the FcgammaIIB receptor on memory B cells in SLE

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Expression pattern of the human FcRH/IRTA receptors in normal tissue and in B-chronic lymphocytic leukemia

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

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5 July 2018

FOXP3: of mice and men.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Epistatic interaction between FCRL3 and NFkappaB1 genes in Spanish patients with rheumatoid arthritis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Restoring function in exhausted CD8 T cells during chronic viral infection

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Supportive evidence for a genetic association of the FCRL3 promoter polymorphism with rheumatoid arthritis

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5 July 2018

Toll-like receptor 8-mediated reversal of CD4+ regulatory T cell function

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5 July 2018

A peripheral circulating compartment of natural naive CD4 Tregs

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5 July 2018

A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2894810

5 July 2018

Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells

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5 July 2018

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

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5 July 2018

The inhibitory potential of Fc receptor homolog 4 on memory B cells

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5 July 2018

Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production

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5 July 2018

IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells

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5 July 2018

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

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5 July 2018

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

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5 July 2018

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

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5 July 2018

The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5.

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5 July 2018

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

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5 July 2018

Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

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Contrasuppression. A novel immunoregulatory activity

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5 July 2018

Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery

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29 October 2018

Anti-TNF-alpha therapy induces a distinct regulatory T cell population in patients with rheumatoid arthritis via TGF-beta

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29 October 2018

Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells

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29 October 2018

Regulation of T cell responses in the developing human fetus

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https://pubmed.ncbi.nlm.nih.gov/20190142

12 December 2020

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Meta-analysis evidence of a differential risk of the FCRL3 -169T-->C polymorphism in white and East Asian rheumatoid arthritis patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20190142

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fc receptor-like 3 -169 C/T polymorphism and RA susceptibility: a meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20190142

12 December 2020

based on heuristic

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Spontaneous autoimmune disease in Fc(gamma)RIIB-deficient mice results from strain-specific epistasis

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https://pubmed.ncbi.nlm.nih.gov/20190142

12 December 2020

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10.4049/JIMMUNOL.0903943

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20190142%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PMC publication ID

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20190142%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20190142%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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