Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity (Q33965112)

30 July 2017

title

Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity (English)

1 reference

30 July 2017

1 reference

D S Franklin

1

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30 July 2017

V L Godfrey

2

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30 July 2017

D A O'Brien

3

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30 July 2017

C Deng

4

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30 July 2017

Y Xiong

5

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30 July 2017

language of work or name

English

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publication date

1 August 2000

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Molecular and Cellular Biology

30 July 2017

published in

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30 July 2017

volume

20

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30 July 2017

issue

16

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30 July 2017

page(s)

6147-6158

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p27 and Rb are on overlapping pathways suppressing tumorigenesis in mice.

30 July 2017

cites work

1 reference

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RB-mediated suppression of spontaneous multiple neuroendocrine neoplasia and lung metastases in Rb+/- mice

5 July 2018

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The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Cellular localization and regulation of expression of testicular estrogen sulfotransferase

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Assay for activity of mammalian cyclin D-dependent kinases CDK4 and CDK6.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

p53, the cellular gatekeeper for growth and division

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

5 July 2018

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The MEN II syndromes and the role of the ret proto-oncogene

5 July 2018

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Induction of p18INK4c and its predominant association with CDK4 and CDK6 during myogenic differentiation

5 July 2018

1 reference

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Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma

5 July 2018

1 reference

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Atm-deficient mice: a paradigm of ataxia telangiectasia

5 July 2018

1 reference

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A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

5 July 2018

1 reference

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Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Spontaneous and carcinogen-induced tumorigenesis in p53-deficient mice.

5 July 2018

1 reference

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WAF1, a potential mediator of p53 tumor suppression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

A cell cycle regulator potentially involved in genesis of many tumor types

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

The retinoblastoma protein and cell cycle control

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Differentiation of adult Leydig cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Radiation-induced cell cycle arrest compromised by p21 deficiency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Chromosome 11q13 abnormalities in human cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Amplification of a gene encoding a p53-associated protein in human sarcomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Tumor surveillance via the ARF-p53 pathway.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Familial multiple endocrine neoplasia syndromes: components, classification, and nomenclature

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Role of the INK4a locus in tumor suppression and cell mortality.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Mice deficient in both p53 and Rb develop tumors primarily of endocrine origin

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86090

Monoclonal antibodies against rat Leydig cell surface antigens

29 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10913196

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cooperative tumorigenic effects of germline mutations in Rb and p53

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10913196

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.20.16.6147-6158.2000

1 reference

30 July 2017

1 reference

30 July 2017

1 reference