Switch in 3' splice site recognition between exon definition and splicing catalysis is important for sex-lethal autoregulation. (Q33967504)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11238934%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

title

Switch in 3' splice site recognition between exon definition and splicing catalysis is important for sex-lethal autoregulation (English)

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5 November 2019

1

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5 November 2019

Juan Valcárcel

series ordinal

3

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5 November 2019

author name string

M J Lallena

series ordinal

2

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5 November 2019

language of work or name

English

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publication date

1 March 2001

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Molecular and Cellular Biology

5 November 2019

published in

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5 November 2019

volume

21

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5 November 2019

issue

6

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5 November 2019

page(s)

1986-1996

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Differential recognition of the polypyrimidine-tract by the general splicing factor U2AF65 and the splicing repressor sex-lethal

5 November 2019

cites work

1 reference

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Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases

5 July 2018

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Structure, function and evolution of sex-determining systems in Dipteran insects

5 July 2018

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The RNA splicing factor hSlu7 is required for correct 3' splice-site choice

5 July 2018

1 reference

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Evidence for a linear search in bimolecular 3' splice site AG selection

5 July 2018

1 reference

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Both subunits of U2AF recognize the 3' splice site in Caenorhabditis elegans

5 July 2018

1 reference

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Functional recognition of the 3' splice site AG by the splicing factor U2AF35.

5 July 2018

1 reference

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Functioning of the Drosophila integral U1/U2 protein Snf independent of U1 and U2 small nuclear ribonucleoprotein particles is revealed by snf(+) gene dose effects

5 July 2018

1 reference

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Evidence for substrate-specific requirement of the splicing factor U2AF(35) and for its function after polypyrimidine tract recognition by U2AF(65).

5 July 2018

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Structural basis for recognition of the tra mRNA precursor by the Sex-lethal protein

5 July 2018

1 reference

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The Drosophila splicing regulator sex-lethal directly inhibits translation of male-specific-lethal 2 mRNA

5 July 2018

1 reference

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Evidence that U5 snRNP recognizes the 3' splice site for catalytic step II in mammals

5 July 2018

1 reference

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Distinct mechanisms of splicing regulation in vivo by the Drosophila protein Sex-lethal

5 July 2018

1 reference

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The regulation of the Drosophila msl-2 gene reveals a function for Sex-lethal in translational control

5 July 2018

1 reference

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Sex lethal controls dosage compensation in Drosophila by a non-splicing mechanism.

5 July 2018

1 reference

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The role of branchpoint-3' splice site spacing and interaction between intron terminal nucleotides in 3' splice site selection in Saccharomyces cerevisiae

5 July 2018

1 reference

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Protein-RNA and protein-protein interactions of the Drosophila sex-lethal mediated by its RNA-binding domains.

5 July 2018

1 reference

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Regulation of the gene Sex-lethal: a comparative analysis of Drosophila melanogaster and Drosophila subobscura.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Directing alternative splicing: cast and scenarios

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Both loss-of-function and gain-of-function mutations in snf define a role for snRNP proteins in regulating Sex-lethal pre-mRNA splicing in Drosophila development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Sex-lethal interacts with splicing factors in vitro and in vivo

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Sex-specific control of Sex-lethal is a conserved mechanism for sex determination in the genus Drosophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Regulated splicing of the Drosophila sex-lethal male exon involves a blockage mechanism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

The Drosophila sex determination gene snf is utilized for the establishment of the female-specific splicing pattern of Sex-lethal

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Scanning and competition between AGs are involved in 3' splice site selection in mammalian introns

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Polypurine sequences within a downstream exon function as a splicing enhancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Specific interactions between proteins implicated in splice site selection and regulated alternative splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Sex-lethal autoregulation requires multiple cis-acting elements upstream and downstream of the male exon and appears to depend largely on controlling the use of the male exon 5' splice site

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

The Drosophila sex determination gene snf encodes a nuclear protein with sequence and functional similarity to the mammalian U1A snRNP protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Exon recognition in vertebrate splicing

5 July 2018

1 reference

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Effects of secondary structure on pre-mRNA splicing: hairpins sequestering the 5' but not the 3' splice site inhibit intron processing in Nicotiana plumbaginifolia.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Male-specific lethal 2, a dosage compensation gene of Drosophila, undergoes sex-specific regulation and encodes a protein with a RING finger and a metallothionein-like cysteine cluster.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Expression of msl-2 causes assembly of dosage compensation regulators on the X chromosomes and female lethality in Drosophila

5 July 2018

1 reference

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Distinct binding specificities and functions of higher eukaryotic polypyrimidine tract-binding proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Prp16p, Slu7p, and Prp8p interact with the 3' splice site in two distinct stages during the second catalytic step of pre-mRNA splicing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Molecular genetics of the achaete-scute gene complex of D. melanogaster.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Scanning from an independently specified branch point defines the 3' splice site of mammalian introns

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Sex-specific alternative splicing of RNA from the transformer gene results from sequence-dependent splice site blockage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Polyoma virus small tumor antigen pre-mRNA splicing requires cooperation between two 3' splice sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Positive autoregulation of sex-lethal by alternative splicing maintains the female determined state in Drosophila.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

A U-rich tract enhances usage of an alternative 3′ splice site in yeast

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Biochemical characterization of U2 snRNP auxiliary factor: an essential pre-mRNA splicing factor with a novel intranuclear distribution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Binding of the Drosophila Sex-lethal gene product to the alternative splice site of transformer primary transcript

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Alterations of RNase H sensitivity of the 3′ splice site region during thein vitrosplicing reaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

The genetic analysis of snf: a Drosophila sex determination gene required for activation of Sex-lethal in both the germline and the soma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Cloning and domain structure of the mammalian splicing factor U2AF

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Control of Drosophila Sex-lethal pre-mRNA splicing by its own female-specific product

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Bimolecular exon ligation by the human spliceosome bypasses early 3' splice site AG recognition and requires NTP hydrolysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3' splice site AG.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Alternative splicing of pre-mRNA: developmental consequences and mechanisms of regulation

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

The role of exon sequences in splice site selection.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

The Sex-lethal amino terminus mediates cooperative interactions in RNA binding and is essential for splicing regulation.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

The msl-2 dosage compensation gene of Drosophila encodes a putative DNA-binding protein whose expression is sex specifically regulated by Sex-lethal

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=86793

Cleavage of 5′ splice site and lariat formation are independent of 3′ splice site in yeast mRNA splicing

29 October 2018

1 reference

12 December 2020

Bimolecular exon ligation by the human spliceosome

1 reference

12 December 2020

The organization of 3' splice-site sequences in mammalian introns

1 reference

12 December 2020

The conserved dinucleotide AG of the 3' splice site may be recognized twice during in vitro splicing of mammalian mRNA precursors

1 reference

12 December 2020

Intron recognition comes of AGe

1 reference

12 December 2020

10.1128/MCB.21.6.1986-1996.2001

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11238934%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11238934%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

PubMed publication ID

11238934

1 reference