NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase (Q33961928)

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English	NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

NF-kappaB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-kappaB-inducing kinase and IkappaB kinase. (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

based on heuristic

inferred from title

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ORCID Public Data File 2021

author name string

M Zamanian-Daryoush

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

T H Mogensen

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

J A DiDonato

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

B R Williams

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

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publication date

1 February 2000

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Europe PubMed Central

PubMed publication ID

30 July 2017

Molecular and Cellular Biology

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Europe PubMed Central

PubMed publication ID

30 July 2017

20

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

1278-1290

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

NF-kappa B is a central regulator of the intestinal epithelial cell innate immune response induced by infection with enteroinvasive bacteria

1 reference

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1 reference

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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

1 reference

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Limb and skin abnormalities in mice lacking IKKalpha

1 reference

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Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

1 reference

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Regulatable expression of the interferon-induced double-stranded RNA dependent protein kinase PKR induces apoptosis and fas receptor expression

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1 reference

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1 reference

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1 reference

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1 reference

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Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappaB activation.

1 reference

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IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex

1 reference

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Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling

1 reference

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Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

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c-Myc is a major mediator of the synergistic growth inhibitory effects of retinoic acid and interferon in breast cancer cells

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Role of IKK1 and IKK2 in lipopolysaccharide signaling in human monocytic cells

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Activation of nuclear factor-kappaB-dependent transcription by tumor necrosis factor-alpha is mediated through phosphorylation of RelA/p65 on serine 529.

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How cells respond to interferons

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1 reference

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1 reference

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

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Epstein-Barr virus-transforming protein latent infection membrane protein 1 activates transcription factor NF-kappaB through a pathway that includes the NF-kappaB-inducing kinase and the IkappaB kinases IKKalpha and IKKbeta

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A mutant cell line defective in response to double-stranded RNA and in regulating basal expression of interferon-stimulated genes

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NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

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IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

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IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

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The double-stranded RNA-dependent protein kinase PKR: structure and function

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I kappa B proteins: structure, function and regulation

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Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

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Identification and characterization of an IkappaB kinase

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A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

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Double-stranded RNA is a trigger for apoptosis in vaccinia virus-infected cells.

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MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1

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Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway

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Transfection of IFNalpha in human glioblastoma cells and tumorigenicity in association with induction of PKR and OAS gene expression

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Suppression of TNF-alpha-induced apoptosis by NF-kappaB

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Initiation of protein synthesis in eukaryotic cells

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Autoregulation of I kappa B alpha activity

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Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

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Rel/NF-kappa B/I kappa B story

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Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

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Involvement of the double-stranded-RNA-dependent kinase PKR in interferon expression and interferon-mediated antiviral activity

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N- and C-terminal sequences control degradation of MAD3/I kappa B alpha in response to inducers of NF-kappa B activity

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IRF-1 induced cell growth inhibition and interferon induction requires the activity of the protein kinase PKR.

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Growth-related expression of a double-stranded RNA-dependent protein kinase in 3T3 cells

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Double-stranded RNA-dependent protein kinase and 2-5A system are both activated in interferon-treated, encephalomyocarditis virus-infected HeLa cells

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The double stranded RNA-activated protein kinase induced by interferon: dsRNA-PK.

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Detection of activated double-stranded RNA-dependent protein kinase in 3T3-F442A cells

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Molecular cloning and characterization of the human double-stranded RNA-activated protein kinase induced by interferon

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Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase

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Constitutive expression of human double-stranded RNA-activated p68 kinase in murine cells mediates phosphorylation of eukaryotic initiation factor 2 and partial resistance to encephalomyocarditis virus growth

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Oncogenic ras induces an inhibitor of double-stranded RNA-dependent eukaryotic initiation factor 2 alpha-kinase activation

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Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85265

5 July 2018

Apoptotic cell death of primed CD45RO+ T lymphocytes in Epstein-Barr virus-induced infectious mononucleosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85265

5 July 2018

Nature of inhibitor of cell-free protein synthesis formed in response to interferon and double-stranded RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85265

5 July 2018

HTLV-I Tax protein binds to MEKK1 to stimulate IkappaB kinase activity and NF-kappaB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85265

29 October 2018

Characterization of the solution complex between the interferon-induced, double-stranded RNA-activated protein kinase and HIV-I trans-activating region RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85265

29 October 2018

Transcription stimulation of the Fas-encoding gene by nuclear factor for interleukin-6 expression upon influenza virus infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=85265

29 October 2018

The interferon-induced double-stranded RNA-activated protein kinase induces apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10648614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B

1 reference

https://pubmed.ncbi.nlm.nih.gov/10648614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transactivation domain 2 (TA2) of p65 NF-kappa B. Similarity to TA1 and phorbol ester-stimulated activity and phosphorylation in intact cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10648614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Further characterization of the protein kinase activity mediated by interferon in mouse and human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10648614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of interferon action. Increased phosphorylation of protein synthesis initiation factor eIF-2 alpha in interferon-treated, reovirus-infected mouse L929 fibroblasts in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/10648614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The apoptosis pathway triggered by the interferon-induced protein kinase PKR requires the third basic domain, initiates upstream of Bcl-2, and involves ICE-like proteases

1 reference

https://pubmed.ncbi.nlm.nih.gov/10648614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/10648614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle regulation of the double stranded RNA activated protein kinase, PKR

1 reference

https://pubmed.ncbi.nlm.nih.gov/10648614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of Double-stranded RNA-activated Protein Kinase in the Synergistic Activation of Nuclear Factor-κB by Tumor Necrosis Factor-α and γ-Interferon in Preneuronal Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10648614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two interferon-induced proteins are involved in the protein kinase complex dependent on double-stranded RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/10648614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Interferon-Induced Double-Stranded RNA-Activated Human p68 Protein Kinase Potently Inhibits Protein Synthesis in Cultured Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10648614

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.20.4.1278-1290.2000

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

0 references

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