HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron (Q44068443)

29 November 2017

title

HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron (English)

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10

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Eamonn R Maher

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Stefano J Mandriota

1

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Kevin J Turner

2

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David R Davies

3

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Paul G Murray

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Heidi M Sowter

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Charles C Wykoff

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Patrick H Maxwell

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publication date

1 June 2002

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volume

1

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issue

5

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page(s)

459-468

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Angiosarcomas express mixed endothelial phenotypes of blood and lymphatic capillaries: podoplanin as a specific marker for lymphatic endothelium

29 November 2017

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

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Somatic mutations of the von Hippel-Lindau disease tumour suppressor gene in non-familial clear cell renal carcinoma

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Mutations of the VHL tumour suppressor gene in renal carcinoma

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

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Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes

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The von Hippel-Lindau tumor suppressor gene

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Identification of the von Hippel-Lindau disease tumor suppressor gene

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

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Activation of the HIF pathway in cancer

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A second major native von Hippel-Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor.

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The von Hippel-Lindau tumor suppressor gene protects cells from UV-mediated apoptosis

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Co-expression of cytokeratin and vimentin intermediate-sized filaments in renal cell carcinomas. Comparative study of the intermediate-sized filament distribution in renal cell carcinomas and normal human kidney

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Renal tubular antigens in kidney tumors

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7 January 2021

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

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7 January 2021

10.1016/S1535-6108(02)00071-5

Identifiers

DOI

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29 November 2017

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