Mutant p62/SQSTM1 UBA domains linked to Paget's disease of bone differ in their abilities to function as stabilization signals (Q44287482)

1 December 2017

title

Mutant p62/SQSTM1 UBA domains linked to Paget's disease of bone differ in their abilities to function as stabilization signals (English)

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1 December 2017

main subject

Paget's disease of bone

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7

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1 December 2017

Nico P Dantuma

9

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Robert Layfield

object named as

Robert Layfield

8

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James R Cavey

object named as

James R Cavey

6

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Stuart H Ralston

5

object named as

Stuart H Ralston

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1 December 2017

3

Jed Long

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1 December 2017

Christian Heinen

1

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1 December 2017

Thomas P Garner

2

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1 December 2017

Claudia Böttcher

4

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1 December 2017

language of work or name

English

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publication date

15 March 2010

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1 December 2017

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volume

584

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1 December 2017

issue

8

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1 December 2017

page(s)

1585-1590

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

1 December 2017

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Mechanisms underlying ubiquitination

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Diversity of degradation signals in the ubiquitin-proteasome system

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Nonproteolytic functions of ubiquitin in cell signaling

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

The ubiquitin receptor Rad23: at the crossroads of nucleotide excision repair and proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

The UBA2 domain functions as an intrinsic stabilization signal that protects Rad23 from proteasomal degradation.

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Proteolysis-independent regulation of the transcription factor Met4 by a single Lys 48-linked ubiquitin chain.

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

A ubiquitin-interacting motif protects polyubiquitinated Met4 from degradation by the 26S proteasome

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Pathogenesis and management of Paget's disease of bone.

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Ubiquitin-mediated signalling and Paget's disease of bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Familial Paget's disease in The Netherlands: occurrence, identification of new mutations in the sequestosome 1 gene, and their clinical associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Two novel mutations at exon 8 of the Sequestosome 1 (SQSTM1) gene in an Italian series of patients affected by Paget's disease of bone (PDB).

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Novel UBA domain mutations of SQSTM1 in Paget's disease of bone: genotype phenotype correlation, functional analysis, and structural consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Three Novel Mutations in SQSTM1 Identified in Familial Paget's Disease of Bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Inhibition of ubiquitin/proteasome-dependent proteolysis in Saccharomyces cerevisiae by a Gly-Ala repeat

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Ubiquitin recognition by the ubiquitin-associated domain of p62 involves a novel conformational switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Characterization of a non-UBA domain missense mutation of sequestosome 1 (SQSTM1) in Paget's disease of bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Substrate-binding sites of UBR1, the ubiquitin ligase of the N-end rule pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Dimerisation of the UBA domain of p62 inhibits ubiquitin binding and regulates NF-kappaB signalling

21 January 2018

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Ubiquitin-binding domains - from structures to functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Recognition and processing of ubiquitin-protein conjugates by the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Recognition of the polyubiquitin proteolytic signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

An unstructured initiation site is required for efficient proteasome-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Proteins are unfolded on the surface of the ATPase ring before transport into the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

A novel mutation (K378X) in the sequestosome 1 gene associated with increased NF-kappaB signaling and Paget's disease of bone with a severe phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Domain-specific mutations in sequestosome 1 (SQSTM1) cause familial and sporadic Paget's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

Loss of Ubiquitin-Binding Associated With Paget's Disease of Bone p62 (SQSTM1) Mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.03.018

10.1016/J.FEBSLET.2010.03.018

21 January 2018

Identifiers

DOI

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1 December 2017

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