Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site (Q44459049)

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scientific article published in June 2003

Language	Label	Description	Also known as
English	Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site	scientific article published in June 2003

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

author name string

L Song

1

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

A Nath

2

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

J D Geiger

3

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

A Moore

4

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

S Hochman

5

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

publication date

1 June 2003

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Journal of NeuroVirology

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Europe PubMed Central

PubMed publication ID

3 December 2017

9

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Europe PubMed Central

PubMed publication ID

3 December 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

399-403

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Europe PubMed Central

PubMed publication ID

3 December 2017

HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

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HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

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Autoantibodies to glutamate receptor GluR3 in Rasmussen's encephalitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

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Detection of the human immunodeficiency virus regulatory protein tat in CNS tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

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Expression of HIV regulatory and structural mRNA in the central nervous system.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

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Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

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Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 Tat causes apoptotic death and calcium homeostasis alterations in rat neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship of trace element, immunological markers, and HIV1 infection progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

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Human immunodeficiency virus type 1 tat activates non-N-methyl-D-aspartate excitatory amino acid receptors and causes neurotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of voltage-independent zinc inhibition of NMDA receptors by the NR1 subunit.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The action of zinc on synaptic transmission and neuronal excitability in cultures of mouse hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exogenous tat protein activates central nervous system-derived endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute in vivo neurotoxicity of peptides from Maedi Visna virus transactivating protein Tat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Actions of ketamine, phencyclidine and MK-801 on NMDA receptor currents in cultured mouse hippocampal neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of inositol 1,4,5-trisphosphate-regulated stores of intracellular calcium in calcium dysregulation and neuron cell death caused by HIV-1 protein tat

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal apoptosis induced by HIV-1 Tat protein and TNF-alpha: potentiation of neurotoxicity mediated by oxidative stress and implications for HIV-1 dementia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity of 5,7-dichlorokynurenic acid, a potent antagonist at the N-methyl-D-aspartate receptor-associated glycine binding site

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-Amino-5-phosphonovalerate (2APV), a potent and selective antagonist of amino acid-induced and synaptic excitation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants for cellular uptake of Tat protein of human immunodeficiency virus type 1 in brain cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Tat protein of HIV-1 induces tumor necrosis factor-alpha production. Implications for HIV-1-associated neurological diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibition of single N-methyl-D-aspartate-activated channels by zinc ions on cultured rat neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutamate receptor antibodies activate a subset of receptors and reveal an agonist binding site

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Magnesium gates glutamate-activated channels in mouse central neurones

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal excitatory properties of human immunodeficiency virus type 1 Tat protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes. A hit and run phenomenon

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxicity of peptide analogues of the transactivating protein tat from Maedi-Visna virus and human immunodeficiency virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential sensitivity of recombinant N-methyl-D-aspartate receptor subtypes to zinc inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurobiological aspects of human immunodeficiency virus infection: neurotoxic mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxic mechanisms of transactivating protein Tat of Maedi-Visna virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a human immunodeficiency virus type 1 Tat epitope that is neuroexcitatory and neurotoxic

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12775422

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1080/13550280390201704

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

Dimensions Publication ID

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

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