Effect of the flavonoids biochanin A and silymarin on the P-glycoprotein-mediated transport of digoxin and vinblastine in human intestinal Caco-2 cells (Q44568334)

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scientific article published in August 2003

Language	Label	Description	Also known as
English	Effect of the flavonoids biochanin A and silymarin on the P-glycoprotein-mediated transport of digoxin and vinblastine in human intestinal Caco-2 cells	scientific article published in August 2003

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Effect of the flavonoids biochanin A and silymarin on the P-glycoprotein-mediated transport of digoxin and vinblastine in human intestinal Caco-2 cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

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inferred from title

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author name string

Shuzhong Zhang

1

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

Marilyn E Morris

2

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Europe PubMed Central

PubMed publication ID

4 December 2017

publication date

1 August 2003

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Europe PubMed Central

PubMed publication ID

4 December 2017

Pharmaceutical Research

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Europe PubMed Central

PubMed publication ID

4 December 2017

20

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Europe PubMed Central

PubMed publication ID

4 December 2017

8

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Europe PubMed Central

PubMed publication ID

4 December 2017

1184-1191

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Europe PubMed Central

PubMed publication ID

4 December 2017

P-glycoprotein-mediated transport of berberine across Caco-2 cell monolayers

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https://pubmed.ncbi.nlm.nih.gov/12948016

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The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer

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https://pubmed.ncbi.nlm.nih.gov/12948016

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Full blockade of intestinal P-glycoprotein and extensive inhibition of blood-brain barrier P-glycoprotein by oral treatment of mice with PSC833

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https://pubmed.ncbi.nlm.nih.gov/12948016

12 December 2020

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Pharmacological insights from P-glycoprotein knockout mice.

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https://pubmed.ncbi.nlm.nih.gov/12948016

12 December 2020

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Biochemical, cellular, and pharmacological aspects of the multidrug transporter

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https://pubmed.ncbi.nlm.nih.gov/12948016

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The effects of dietary supplementation with isoflavones from red clover on the lipoprotein profiles of post menopausal women with mild to moderate hypercholesterolaemia

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https://pubmed.ncbi.nlm.nih.gov/12948016

12 December 2020

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Silymarin, a naturally occurring polyphenolic antioxidant flavonoid, inhibits azoxymethane-induced colon carcinogenesis in male F344 rats

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https://pubmed.ncbi.nlm.nih.gov/12948016

12 December 2020

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Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

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Effect of milk thistle on the pharmacokinetics of indinavir in healthy volunteers

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P-glycoprotein--a mediator of multidrug resistance in tumour cells

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In vitro techniques for studying drug metabolism

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Acute heart transplant rejection due to Saint John's wort

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Dietary effects on breast-cancer risk in Singapore

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Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

12 December 2020

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Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

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Transport of the flavonoid chrysin and its conjugated metabolites by the human intestinal cell line Caco-2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

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Utilization of complementary and alternative medicine by United States adults: results from the 1999 national health interview survey

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Perceptions about complementary therapies relative to conventional therapies among adults who use both: results from a national survey

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Are MDCK cells transfected with the human MRP2 gene a good model of the human intestinal mucosa?

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https://pubmed.ncbi.nlm.nih.gov/12948016

12 December 2020

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The biochemistry and medical significance of the flavonoids

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https://pubmed.ncbi.nlm.nih.gov/12948016

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Clinical relevance of transmembrane drug efflux as a mechanism of multidrug resistance.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

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Effect of cyclosporine on colchicine secretion by the kidney multidrug transporter studied in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

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Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-glycoprotein as a putative mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

12 December 2020

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Isoflavones from red clover (Promensil) significantly reduce menopausal hot flush symptoms compared with placebo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Milk thistle for the treatment of liver disease: a systematic review and meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

12 December 2020

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A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

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Inhibition of P-glycoprotein-mediated drug transport: A unifying mechanism to explain the interaction between digoxin and quinidine [seecomments]

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

12 December 2020

based on heuristic

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A functional assay for quantitation of the apparent affinities of ligands of P-glycoprotein in Caco-2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

12 December 2020

based on heuristic

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Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

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Are MDCK cells transfected with the human MDR1 gene a good model of the human intestinal mucosa?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

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Use of herbs in women diagnosed with ovarian cancer

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Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target

1 reference

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Multidrug resistance in cells transfected with human genes encoding a variant P-glycoprotein and glutathione S-transferase-pi

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

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Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

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The effect of grapefruit juice and seville orange juice on the pharmacokinetics of dextromethorphan: the role of gut CYP3A and P-glycoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

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Indinavir concentrations and St John's wort.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12948016

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1025044913766

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 December 2017

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