Simvastatin induces apoptosis of B-CLL cells by activation of mitochondrial caspase 9. (Q44577513)

4 December 2017

title

Simvastatin induces apoptosis of B-CLL cells by activation of mitochondrial caspase 9. (English)

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B-cell chronic lymphocytic leukemia

4 December 2017

main subject

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Daphne Chapman-Shimshoni

1

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4 December 2017

Mona Yuklea

2

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4 December 2017

Judith Radnay

3

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4 December 2017

Hava Shapiro

4

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4 December 2017

Michael Lishner

5

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4 December 2017

publication date

1 September 2003

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4 December 2017

language of work

Experimental Hematology

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4 December 2017

volume

31

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4 December 2017

issue

9

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4 December 2017

page(s)

779-783

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Chronic lymphocytic leukemia

4 December 2017

cites work

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7 January 2021

The Bcl-2 protein family: arbiters of cell survival

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7 January 2021

Processing/activation of caspases, -3 and -7 and -8 but not caspase-2, in the induction of apoptosis in B-chronic lymphocytic leukemia cells

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https://api.crossref.org/works/10.1016%2FS0301-472X%2803%2900192-9

7 January 2021

Non-lipid-related effects of statins

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7 January 2021

HMG-CoA reductase inhibitors: role in normal and malignant cells

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7 January 2021

HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis

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https://api.crossref.org/works/10.1016%2FS0301-472X%2803%2900192-9

7 January 2021

Effect of simvastatin alone and in combination with cytosine arabinoside on the proliferation of myeloid leukemia cell lines

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7 January 2021

A comparison of the effect of the 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors simvastatin, lovastatin and pravastatin on leukaemic and normal bone marrow progenitors

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https://api.crossref.org/works/10.1016%2FS0301-472X%2803%2900192-9

7 January 2021

The antiapoptotic effects of blood constituents in patients with chronic lymphocytic leukemia

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https://api.crossref.org/works/10.1016%2FS0301-472X%2803%2900192-9

7 January 2021

Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an approximately 700 kDa Apaf-1 containing apoptosome complex

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https://api.crossref.org/works/10.1016%2FS0301-472X%2803%2900192-9

7 January 2021

FLICE is predominantly expressed as two functionally active isoforms, caspase-8/a and caspase-8/b.

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https://api.crossref.org/works/10.1016%2FS0301-472X%2803%2900192-9

7 January 2021

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

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7 January 2021

Nucleotide requirements for the in vitro activation of the apoptosis protein-activating factor-1-mediated caspase pathway

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7 January 2021

Mitochondria and apoptosis

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7 January 2021

The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: evidence of caspase activation and apoptosis induction

1 reference

https://api.crossref.org/works/10.1016%2FS0301-472X%2803%2900192-9

7 January 2021

Role of the CD40 and CD95 (APO-1/Fas) antigens in the apoptosis of human B-cell malignancies

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7 January 2021

Impaired low-density lipoprotein receptor activity in chronic B-lymphocytic leukaemia cells

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7 January 2021

10.1016/S0301-472X(03)00192-9

Identifiers

DOI

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4 December 2017

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