Metallothionein protects islets from hypoxia and extends islet graft survival by scavenging most kinds of reactive oxygen species (Q44630383)

4 December 2017

title

Metallothionein protects islets from hypoxia and extends islet graft survival by scavenging most kinds of reactive oxygen species (English)

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4 December 2017

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reactive oxygen species

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3

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4 December 2017

Xiaoyan Li

1

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4 December 2017

Hainan Chen

series ordinal

2

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4 December 2017

language of work or name

English

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publication date

23 October 2003

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Journal of Biological Chemistry

4 December 2017

published in

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4 December 2017

volume

279

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4 December 2017

issue

1

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4 December 2017

page(s)

765-771

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Human islet cell transplantation--future prospects

4 December 2017

cites work

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Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site

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Lazaroids improve the survival of grafted rat embryonic dopamine neurons

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How can adenovirus-mediated catalase and superoxide dismutase gene transfer improve the outcome of pancreatic cells for transplantation?

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Determinants of the selective toxicity of alloxan to the pancreatic B cell

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Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury

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Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.

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Influence of antioxidant therapy on islet graft survival

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Overexpression of metallothionein in pancreatic beta-cells reduces streptozotocin-induced DNA damage and diabetes

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Free radical scavenging actions of metallothionein isoforms I and II.

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Metallothionein prevents diabetes-induced deficits in cardiomyocytes by inhibiting reactive oxygen species production

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Evaluation of hepatic subcellular fractions for Alamar blue and MTT reductase activity

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Assessment of a simple, non-toxic Alamar blue cell survival assay to monitor tomato cell viability.

21 January 2018

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Beta cell mass and growth after syngeneic islet cell transplantation in normal and streptozocin diabetic C57BL/6 mice

21 January 2018

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Reactive species mechanisms of cellular hypoxia-reoxygenation injury

21 January 2018

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Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes.

21 January 2018

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Chronically decreased oxygen tension in rat pancreatic islets transplanted under the kidney capsule

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Impairment of glucose-induced insulin secretion in human pancreatic islets transplanted to diabetic nude mice

21 January 2018

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Protection of insulin-producing RINm5F cells against cytokine-mediated toxicity through overexpression of antioxidant enzymes

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Role of metallothionein and other antioxidants in scavenging superoxide radicals and their possible role in neuroprotection

21 January 2018

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Apoptosis in hypoxic human pancreatic islets correlates with HIF-1alpha expression

21 January 2018

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Influence of experimental hyperglycemia on microvascular blood perfusion of pancreatic islet isografts

21 January 2018

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Islet graft primary nonfunction and its prevention.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M307907200

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4 December 2017

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