Cell cycle activation linked to neuronal cell death initiated by DNA damage (Q44774050)

6 December 2017

title

Cell cycle activation linked to neuronal cell death initiated by DNA damage (English)

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6 December 2017

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8

Myriam Gorospe

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6 December 2017

9

Mark P Mattson

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6 December 2017

Inna I Kruman

1

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6 December 2017

Robert P Wersto

2

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6 December 2017

Fernando Cardozo-Pelaez

3

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6 December 2017

Lubomir Smilenov

4

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6 December 2017

Sic L Chan

5

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6 December 2017

Francis J Chrest

6

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6 December 2017

Roland Emokpae

7

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6 December 2017

language of work or name

English

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publication date

1 February 2004

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6 December 2017

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6 December 2017

volume

41

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6 December 2017

issue

4

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6 December 2017

page(s)

549-561

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DNA strand breaks in Alzheimer's disease.

6 December 2017

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Atm-deficient mice: a paradigm of ataxia telangiectasia

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Caffeine inhibits the checkpoint kinase ATM

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Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases

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7 January 2021

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

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Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

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7 January 2021

Role of the Cdc25A phosphatase in human breast cancer

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7 January 2021

Attenuation of age-dependent oxidative damage to DNA and protein in brainstem of Tg Cu/Zn SOD mice

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7 January 2021

DNA damage, repair, and antioxidant systems in brain regions: a correlative study

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7 January 2021

Heterogeneous expression of Ku70 in human tissues is associated with morphological and functional alterations of the nucleus.

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7 January 2021

Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system

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7 January 2021

Mitotic signaling by beta-amyloid causes neuronal death

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7 January 2021

Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path?

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7 January 2021

Is it all DNA repair? Methodological considerations for detecting neurogenesis in the adult brain

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7 January 2021

On the nature of a defect in cells from individuals with ataxia-telangiectasia

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7 January 2021

A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

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7 January 2021

The cell cycle Cdc25A tyrosine phosphatase is activated in degenerating postmitotic neurons in Alzheimer's disease

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7 January 2021

Dual mode of degradation of Cdc25 A phosphatase

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7 January 2021

A de novo designed helix-turn-helix peptide forms nontoxic amyloid fibrils

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7 January 2021

Two Pathways for Base Excision Repair in Mammalian Cells

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7 January 2021

Increased nuclear DNA oxidation in the brain in Alzheimer's disease

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7 January 2021

Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins

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7 January 2021

Cdc25 cell-cycle phosphatase as a target of c-myc

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7 January 2021

Response of postmitotic neurons to X-irradiation: implications for the role of DNA damage in neuronal apoptosis.

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7 January 2021

Cytochrome c release and caspase-3 activation during colchicine-induced apoptosis of cerebellar granule cells

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7 January 2021

Methotrexate-induced misincorporation of uracil into DNA.

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7 January 2021

Genomic heterogeneity of DNA repair. Role in aging?

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7 January 2021

Phosphorylation of retinoblastoma protein in rat brain after transient middle cerebral artery occlusion

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7 January 2021

Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system

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7 January 2021

Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition

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7 January 2021

Identification of apoptotic and necrotic human leukemic cells by flow cytometry

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7 January 2021

Mitotic activation: a convergent mechanism for a cohort of neurodegenerative diseases

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7 January 2021

Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death.

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7 January 2021

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

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7 January 2021

Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity

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7 January 2021

Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease.

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7 January 2021

Detection of apoptosis and DNA replication by differential labeling of DNA strand breaks with fluorochromes of different color

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7 January 2021

Neuronal apoptosis at the G1/S cell cycle checkpoint

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7 January 2021

Increased DNA oxidation and decreased levels of repair products in Alzheimer's disease ventricular CSF.

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7 January 2021

Reduced NMDA-induced apoptosis in neurons lacking ataxia telangiectasia mutated protein

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7 January 2021

Apoptosis in neurodegenerative disorders

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7 January 2021

Calcium-destabilizing and neurodegenerative effects of aggregated beta-amyloid peptide are attenuated by basic FGF.

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7 January 2021

Control of DNA Repair Linked to Neuroblastoma Differentiation

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7 January 2021

Re-entry into the cell cycle: a mechanism for neurodegeneration in Alzheimer disease.

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7 January 2021

Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: evidence for cell cycle-independent toxicity

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7 January 2021

Optimization of single-cell gel electrophoresis (SCGE) for quantitative analysis of neuronal DNA damage

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7 January 2021

Induction of oxidative DNA damage in the peri-infarct region after permanent focal cerebral ischemia

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7 January 2021

A sequence in the N-terminal region of human uracil-DNA glycosylase with homology to XPA interacts with the C-terminal part of the 34-kDa subunit of replication protein A

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7 January 2021

Terminally differentiated human neurons repair transcribed genes but display attenuated global DNA repair and modulation of repair gene expression

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7 January 2021

Post-replicative base excision repair in replication foci

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7 January 2021

Cyclin dependent kinase inhibitors and dominant negative cyclin dependent kinase 4 and 6 promote survival of NGF-deprived sympathetic neurons

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7 January 2021

Cyclin-dependent kinases participate in death of neurons evoked by DNA-damaging agents

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7 January 2021

Checkpoints: it takes more than time to heal some wounds

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7 January 2021

Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition.

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7 January 2021

Linking DNA damage and neurodegeneration

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7 January 2021

Contribution of apoptosis to responses in the comet assay

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7 January 2021

ATM: from gene to function

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7 January 2021

Intrathecal chemotherapy with antineoplastic agents in children

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7 January 2021

Increased apoptosis rate by hyperthermochemoradiotherapy for advanced rectal cancers

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7 January 2021

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

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7 January 2021

A rate limiting function of cdc25A for S phase entry inversely correlates with tyrosine dephosphorylation of Cdk2

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7 January 2021

ATM: genome stability, neuronal development, and cancer cross paths

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7 January 2021

A high easy-to-treat complication rate is the price for continent stoma

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7 January 2021

Comparison of base-excision repair capacity in proliferating and differentiated PC 12 cells following acute challenge with dieldrin

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7 January 2021

Involvement of DNA damage and repair systems in neurodegenerative process.

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7 January 2021

Localization of the colchicine-binding site of tubulin

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7 January 2021

Downstream molecular determinants of response to 5-fluorouracil and antifolate thymidylate synthase inhibitors.

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7 January 2021

The therapeutic potential of poly(ADP-ribose) polymerase inhibitors

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7 January 2021

E2F-1 and a cyclin-like DNA repair enzyme, uracil-DNA glycosylase, provide evidence for an autoregulatory mechanism for transcription

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7 January 2021

Staurosporine-induced apoptosis is independent of p16 and p21 and achieved via arrest at G2/M and at G1 in U251MG human glioma cell line

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7 January 2021

DNA replication precedes neuronal cell death in Alzheimer's disease.

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7 January 2021

10.1016/S0896-6273(04)00017-0

Identifiers

DOI

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6 December 2017

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