Insulin suppresses PDK-4 expression in skeletal muscle independently of plasma FFA. (Q44802852)

6 December 2017

title

Insulin suppresses PDK-4 expression in skeletal muscle independently of plasma FFA. (English)

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6 December 2017

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Felix N Lee

1

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6 December 2017

Lihua Zhang

2

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6 December 2017

Dan Zheng

3

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6 December 2017

Woo S Choi

4

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6 December 2017

Jang H Youn

5

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6 December 2017

publication date

16 March 2004

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American Journal of Physiology - Endocrinology and Metabolism

6 December 2017

published in

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6 December 2017

volume

287

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6 December 2017

issue

1

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6 December 2017

page(s)

E69-74

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Lactate induces insulin resistance in skeletal muscle by suppressing glycolysis and impairing insulin signaling

6 December 2017

cites work

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00461.2003

Free fatty acids induce peripheral insulin resistance without increasing muscle hexosamine pathway product levels in rats

21 January 2018

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Role of lipid oxidation in pathogenesis of insulin resistance of obesity and type II diabetes.

21 January 2018

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Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

21 January 2018

1 reference

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Reversible phosphorylation of pyruvate dehydrogenase in rat skeletal-muscle mitochondria. Effects of starvation and diabetes

21 January 2018

1 reference

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Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00461.2003

Diversity of the pyruvate dehydrogenase kinase gene family in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00461.2003

Up-regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) protein expression in oxidative skeletal muscle does not require the obligatory participation of peroxisome-proliferator-activated receptor alpha (PPARalpha).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00461.2003

Protein kinase B-alpha inhibits human pyruvate dehydrogenase kinase-4 gene induction by dexamethasone through inactivation of FOXO transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00461.2003

Insulin downregulates pyruvate dehydrogenase kinase (PDK) mRNA: potential mechanism contributing to increased lipid oxidation in insulin-resistant subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00461.2003

Insulin-induced phosphorylation of FKHR (Foxo1) targets to proteasomal degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00461.2003

Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00461.2003

Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00461.2003

Cloning and characterization of PDK4 on 7q21.3 encoding a fourth pyruvate dehydrogenase kinase isoenzyme in human

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00461.2003

Essentiality of circulating fatty acids for glucose-stimulated insulin secretion in the fasted rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00461.2003

Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00461.2003

Adaptive increase in pyruvate dehydrogenase kinase 4 during starvation is mediated by peroxisome proliferator-activated receptor alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00461.2003

10.1152/AJPENDO.00461.2003

21 January 2018

Identifiers

DOI

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release_ail5zlmmovcprkmourn5vjktyq

6 December 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/ail5zlmmovcprkmourn5vjktyq

mapped directly with Wikidata item

24 November 2022

based on heuristic

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