Kinetic analysis of 5-fluorouracil action against various cancer cells (Q44885986)

23 June 2018

title

Kinetic analysis of 5-fluorouracil action against various cancer cells (English)

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23 June 2018

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M Inaba

1

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23 June 2018

J Mitsuhashi

series ordinal

2

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23 June 2018

S Ozawa

series ordinal

3

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23 June 2018

publication date

1 October 1990

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23 June 2018

number of pages

6

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Japanese Journal of Cancer Research

inferred from page(s)

published in

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23 June 2018

volume

81

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23 June 2018

issue

10

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23 June 2018

page(s)

1039-1044

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23 June 2018

Treatment of cultured human colon carcinoma cells with fluorinated pyrimidines

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5917971

In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas.

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5917971

Cell killing action of cell cycle phase-non-specific antitumor agents is dependent on concentration--time product.

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5917971

Relationship between 5-fluoro-2'-deoxyuridylate, 2'-deoxyuridylate, and thymidylate synthase activity subsequent to 5-fluorouracil administration, in xenografts of human colon adenocarcinomas

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5917971

Mechanism of the cytotoxic synergism of fluoropyrimidines and folinic acid in mouse leukemic cells

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5917971

Kinetic analysis of cell killing effect induced by cytosine arabinoside and cisplatin in relation to cell cycle phase specificity in human colon cancer and Chinese hamster cells.

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5917971

Correlation between ribosomal RNA production and RNA-directed fluoropyrimidine cytotoxicity

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5917971

Effects of 5-fluorouracil on 5-fluorodeoxyuridine 5'-monophosphate and 2-deoxyuridine 5'-monophosphate pools, and DNA synthesis in solid mouse L1210 and rat Walker 256 tumors

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5917971

Effect of 5-fluorouracil on RNA metabolism in Novikoff hepatoma cells

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5917971

Thymidylate synthetase inhibition in malignant tumors and normal liver of patients given intravenous 5-fluorouracil.

24 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5917971

The cytotoxicity of 5-fluorouracil is due to its incorporation into RNA not its inhibition of thymidylate synthase as evidenced by the use of a mouse cell mutant deficient in thymidylate synthase

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5917971

Binding of 5-fluorodeoxyuridylate to thymidylate synthase in human colon adenocarcinoma xenografts

15 August 2018

1 reference

12 December 2020

Cytotoxicity and the inhibition of ribosomal RNA processing in human colon carcinoma cells

1 reference

12 December 2020

Cell cycle phase specificity of antitumor agents

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12 December 2020

Relationship of cellular folate cofactor pools to the activity of 5-fluorouracil

1 reference

12 December 2020

On the mechanism of cytotoxicity of fluorinated pyrimidines in four human colon adenocarcinoma xenografts maintained in immune-deprived mice

1 reference

12 December 2020

The inhibitory effects of 5-fluorouracil on the metabolism of preribosomal and ribosomal RNA in L-1210 cells in vitro

1 reference

12 December 2020

Assessment of growth-limiting events caused by 5-fluorouracil in mouse cells and in human cells

1 reference

12 December 2020

Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinomas in mice

1 reference

12 December 2020

Effect of excess folates and deoxyinosine on the activity and site of action of 5-fluorouracil

1 reference

12 December 2020

Association of cell lethality with incorporation of 5-fluorouracil and 5-fluorouridine into nuclear RNA in human colon carcinoma cells in culture

1 reference

12 December 2020

Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by 5-fluorouracil and 5-fluorouridine

1 reference

12 December 2020

Lethality associated with incorporation of 5-fluorouracil into preribosomal RNA

1 reference

12 December 2020

5-Fluorouracil incorporation into human breast carcinoma RNA correlates with cytotoxicity

1 reference

12 December 2020

Mechanisms of sensitivity and resistance of murine tumors to 5-fluorouracil

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12 December 2020

Precursor-dependent differences in the incorporation of fluorouracil in RNA

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12 December 2020

Comparison of 5-fluorouracil metabolism in two human gastrointestinal tumor cell lines

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12 December 2020

Relationship of dUMP and free FdUMP pools to inhibition of thymidylate synthase by 5-fluorouracil

1 reference

12 December 2020

10.1111/J.1349-7006.1990.TB03343.X

Identifiers

DOI

1 reference

23 June 2018

PMC publication ID

5917971

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23 June 2018

PubMed publication ID

2146239

1 reference

23 June 2018