Promiscuity in the geometry of electrostatic interactions between the Escherichia coli multidrug resistance transporter MdfA and cationic substrates (Q45158676)

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scientific article published on 22 November 2004

Language	Label	Description	Also known as
English	Promiscuity in the geometry of electrostatic interactions between the Escherichia coli multidrug resistance transporter MdfA and cationic substrates	scientific article published on 22 November 2004

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Promiscuity in the geometry of electrostatic interactions between the Escherichia coli multidrug resistance transporter MdfA and cationic substrates (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

multiple drug resistance

1 reference

based on heuristic

inferred from title

Escherichia coli

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based on heuristic

inferred from title

author name string

Julia Adler

1

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Eitan Bibi

2

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

language of work or name

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publication date

22 November 2004

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Europe PubMed Central

PubMed publication ID

10 December 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

10 December 2017

280

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Europe PubMed Central

PubMed publication ID

10 December 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

2721-2729

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

Efflux-mediated drug resistance in Gram-positive bacteria

1 reference

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Active efflux, a common mechanism for biocide and antibiotic resistance

1 reference

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Mechanism of antibiotic efflux in Gram-negative bacteria.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

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Structural mechanisms of QacR induction and multidrug recognition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

Structural mechanism of the simultaneous binding of two drugs to a multidrug-binding protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

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Crystal structures of QacR-diamidine complexes reveal additional multidrug-binding modes and a novel mechanism of drug charge neutralization

1 reference

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21 January 2018

Structural Basis of Multiple Drug-Binding Capacity of the AcrB Multidrug Efflux Pump

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

Structure of the multidrug resistance efflux transporter EmrE from Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

MdfA, an Escherichia coli multidrug resistance protein with an extraordinarily broad spectrum of drug recognition

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157

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21 January 2018

Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18

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Role of a conserved membrane-embedded acidic residue in the multidrug transporter MdfA.

1 reference

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21 January 2018

Evidence for chloramphenicol/H+ antiport in Cmr (MdfA) system of Escherichia coli and properties of the antiporter

1 reference

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21 January 2018

The Escherichia coli multidrug transporter MdfA catalyzes both electrogenic and electroneutral transport reactions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

A single membrane-embedded negative charge is critical for recognizing positively charged drugs by the Escherichia coli multidrug resistance protein MdfA.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

Membrane topology of the multidrug transporter MdfA: complementary gene fusion studies reveal a nonessential C-terminal domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

Evidence for simultaneous binding of dissimilar substrates by the Escherichia coli multidrug transporter MdfA.

1 reference

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21 January 2018

Alkalitolerance: a biological function for a multidrug transporter in pH homeostasis.

1 reference

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21 January 2018

Determinants of substrate recognition by the Escherichia coli multidrug transporter MdfA identified on both sides of the membrane.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

An essential glutamyl residue in EmrE, a multidrug antiporter from Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

Functional expression of mouse mdr1 in Escherichia coli

1 reference

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21 January 2018

Pegylation: a method for assessing topological accessibilities in Kv1.3.

1 reference

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21 January 2018

Functional expression of mouse Mdr1 in an outer membrane permeability mutant of Escherichia coli.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

In vivo expression of the lacY gene in two segments leads to functional lac permease

1 reference

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21 January 2018

A General Method for Mapping Tertiary Contacts between Amino Acid Residues in Membrane-Embedded Proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

Multidrug resistance proteins QacA and QacB from Staphylococcus aureus: membrane topology and identification of residues involved in substrate specificity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

A membrane-embedded glutamate is required for ligand binding to the multidrug transporter EmrE

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

Acidic residues in the lactococcal multidrug efflux pump LmrP play critical roles in transport of lipophilic cationic compounds

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

Quantitative evaluation of the lengths of homobifunctional protein cross-linking reagents used as molecular rulers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

Helix packing in the lactose permease of Escherichia coli determined by site-directed thiol cross-linking: helix I is close to helices V and XI.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

Structural model for 12-helix transporters belonging to the major facilitator superfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli

1 reference

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21 January 2018

Site-specificity of the second-site suppressor mutation of the Asp-285-->Asn mutant of metal-tetracycline/H+ antiporter of Escherichia coli and the effects of amino acid substitutions at the first and second sites.

1 reference

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21 January 2018

Biotinylation of single cysteine mutants of the glutamate transporter GLT-1 from rat brain reveals its unusual topology

1 reference

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Conserved residues R420 and Q428 in a cytoplasmic loop of the citrate/malate transporter CimH of Bacillus subtilis are accessible from the external face of the membrane

1 reference

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21 January 2018

Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding sta

1 reference

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21 January 2018

An amino acid cluster around the essential Glu-14 is part of the substrate- and proton-binding domain of EmrE, a multidrug transporter from Escherichia coli.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M412332200

21 January 2018

Identifiers

10.1074/JBC.M412332200

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 December 2017

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