UGT1A1*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients. (Q46038296)

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scientific article published on 24 April 2009

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English	UGT1A1*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients.	scientific article published on 24 April 2009

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scholarly article

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stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

title

UGT1A1*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients (English)

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stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

main subject

irinotecan

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based on heuristic

inferred from title

author

Satoshi Teramukai

series ordinal

9

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

author name string

Masahide Onoue

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

Tomohiro Terada

series ordinal

2

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stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

Masahiko Kobayashi

series ordinal

3

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stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

Toshiya Katsura

series ordinal

4

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

Shigemi Matsumoto

series ordinal

5

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

Kazuhiro Yanagihara

series ordinal

6

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

Takafumi Nishimura

series ordinal

7

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stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

Masashi Kanai

series ordinal

8

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

Akira Shimizu

series ordinal

10

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

Masanori Fukushima

series ordinal

11

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

Ken-ichi Inui

series ordinal

12

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

publication date

24 April 2009

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

published in

International Journal of Clinical Oncology

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

volume

14

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

issue

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

page(s)

136-142

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

cites work

UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetics of SLCO1B1 gene and the impact of *1b and *15 haplotypes on irinotecan disposition in Asian cancer patients

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of neonatal hyperbilirubinemia with bilirubin UDP-glucuronosyltransferase polymorphism

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38) by the human UDP-glucuronosyltransferases encoded at the UGT1 locus

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic linkage of UGT1A7 and UGT1A9 polymorphisms to UGT1A1*6 is associated with reduced activity for SN-38 in Japanese patients with cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetics of human carboxylesterase 2, an enzyme involved in the activation of irinotecan into SN-38

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetics and irinotecan therapy

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic variation in bilirubin UPD-glucuronosyltransferase gene promoter and Gilbert's syndrome

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of SN-38 exposure, UGT1A1*28 polymorphism, and baseline bilirubin level in predicting severe irinotecan toxicity

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Racial variability in haplotype frequencies of UGT1A1 and glucuronidation activity of a novel single nucleotide polymorphism 686C> T (P229L) found in an African-American

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The UGT1A1*28 allele is relatively rare in a Japanese population

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of organic anion transporter OATP1B1 (OATP-C) in hepatic uptake of irinotecan and its active metabolite, 7-ethyl-10-hydroxycamptothecin: in vitro evidence and effect of single nucleotide polymorphisms.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pravastatin, an HMG-CoA reductase inhibitor, is transported by rat organic anion transporting polypeptide, oatp2.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gilbert syndrome accelerates development of neonatal jaundice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irinotecan plus cisplatin compared with etoposide plus cisplatin for extensive small-cell lung cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetic impact of polymorphisms in the coding region of the UGT1A1 gene on SN-38 glucuronidation in Japanese patients with cancer.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38).

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neonatal hyperbilirubinemia and a common mutation of the bilirubin uridine diphosphate-glucuronosyltransferase gene in Japanese

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic therapy for colorectal cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irinotecan-induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UGT1A1*28 genotype and irinotecan-induced neutropenia: dose matters

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/19390945

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S10147-008-0821-Z

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

PubMed publication ID

19390945

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19390945

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19390945%20AND%20SRC:MED&resulttype=core&format=json

retrieved

26 January 2020

ResearchGate publication ID

24356366

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