The role of tyrosine phosphorylation and PTP-1C in CTLA-4 signal transduction. (Q46125201)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8977326%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

title

The role of tyrosine phosphorylation and PTP-1C in CTLA-4 signal transduction (English)

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22 October 2019

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2

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22 October 2019

author name string

C A Chambers

series ordinal

1

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22 October 2019

language of work or name

English

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publication date

1 December 1996

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8977326%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Immunology

22 October 2019

published in

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22 October 2019

volume

26

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22 October 2019

issue

12

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22 October 2019

page(s)

3224-3229

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The role of the CD28 receptor during T cell responses to antigen

22 October 2019

cites work

1 reference

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Protein tyrosine phosphatase containing SH2 domains: characterization, preferential expression in hematopoietic cells, and localization to human chromosome 12p12-p13.

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Lck-dependent tyrosyl phosphorylation of the phosphotyrosine phosphatase SH-PTP1 in murine T cells

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CD28-B7 interactions in T-cell activation.

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7 January 2021

CTLA-4 can function as a negative regulator of T cell activation

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CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

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7 January 2021

CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells

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CTLA-4 ligation blocks CD28-dependent T cell activation

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7 January 2021

Superantigen responses and co-stimulation: CD28 and CTLA-4 have opposing effects on T cell expansion in vitro and in vivo

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7 January 2021

Enhancement of antitumor immunity by CTLA-4 blockade

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Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

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7 January 2021

A new member of the immunoglobulin superfamily--CTLA-4

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Upstream-downstream: CD28 cosignaling pathways and T cell function

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Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

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7 January 2021

Of ITAMs and ITIMs: turning on and off the B cell antigen receptor

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Recruitment and activation of PTP1C in negative regulation of antigen receptor signaling by Fc gamma RIIB1.

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7 January 2021

Recruitment of tyrosine phosphatase HCP by the killer cell inhibitor receptor

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7 January 2021

Isolation of a src homology 2-containing tyrosine phosphatase

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7 January 2021

Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4

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7 January 2021

Phorbol diester receptor copurifies with protein kinase C

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7 January 2021

Stimulation of p21 ras upon T-cell activation

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7 January 2021

Defective expression of hematopoietic cell protein tyrosine phosphatase (HCP) in lymphoid cells blocks Fas-mediated apoptosis

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7 January 2021

Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene

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7 January 2021

Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene

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7 January 2021

Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice

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7 January 2021

Pleiotropic Effects of Deleterious Alleles at the “Motheaten” Locus

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7 January 2021

A monoclonal antibody detecting an Ia specificity mapping in the I-A or I-E subregion

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7 January 2021

CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones

1 reference

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7 January 2021

Activation and differentiation requirements of primary T cells in vitro

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7 January 2021

T cell antigen receptor signal transduction pathways

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7 January 2021

Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signaling

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7 January 2021

Identifiers

DOI

10.1002/EJI.1830261257

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8977326%20AND%20SRC:MED&resulttype=core&format=json

22 October 2019

1 reference