Raf-1-induced growth arrest in human mammary epithelial cells is p16-independent and is overcome in immortal cells during conversion (Q46230264)

20 December 2017

title

Raf-1-induced growth arrest in human mammary epithelial cells is p16-independent and is overcome in immortal cells during conversion (English)

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20 December 2017

author name string

Catherine L Olsen

1

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20 December 2017

Betty Gardie

2

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20 December 2017

Paul Yaswen

3

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20 December 2017

Martha R Stampfer

4

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20 December 2017

language of work or name

English

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publication date

1 September 2002

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20 December 2017

published in

Oncogene

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20 December 2017

volume

21

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20 December 2017

issue

41

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20 December 2017

page(s)

6328-6339

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20 December 2017

Increased p16 expression with first senescence arrest in human mammary epithelial cells and extended growth capacity with p16 inactivation

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Viral oncogenes accelerate conversion to immortality of cultured conditionally immortal human mammary epithelial cells

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Raf-1 protein kinase is required for growth of induced NIH/3T3 cells

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Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts

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Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

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Cooperating oncogenes converge to regulate cyclin/cdk complexes.

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Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)

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Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes

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p19ARF-independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes

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Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

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Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells

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Constitutive Raf-1 kinase activity in breast cancer cells induces both estrogen-independent growth and apoptosis

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Raf-1-induced cell cycle arrest in LNCaP human prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205780

inferred from DOI database lookup

7 January 2021

based on heuristic

Isolation and growth of human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205780

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1205780

1 reference

20 December 2017

1 reference

20 December 2017