Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis. (Q46352618)

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22 March 2020

title

Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis (English)

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22 March 2020

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Malte Christoph Rühlemann

3

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22 March 2020

Femke-Anouska Heinsen

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Andre Franke

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Joerg Heeren

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Claus Kremoser

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22 March 2020

author name string

Anna Worthmann

1

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Clara John

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22 March 2020

Miriam Baguhl

4

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Nicola Schaltenberg

6

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Markus Heine

7

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Christian Schlein

8

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22 March 2020

Ioannis Evangelakos

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Chieko Mineo

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Markus Fischer

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Maura Dandri

12

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Ludger Scheja

14

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Philip W Shaul

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language of work or name

English

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publication date

12 June 2017

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22 March 2020

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22 March 2020

volume

23

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issue

7

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22 March 2020

page(s)

839-849

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An obesity-associated gut microbiome with increased capacity for energy harvest

22 March 2020

cites work

1 reference

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Diet dominates host genotype in shaping the murine gut microbiota

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Gut Microbiota Orchestrates Energy Homeostasis during Cold.

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Altered Microbiota Contributes to Reduced Diet-Induced Obesity upon Cold Exposure

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Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development.

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The enzymes, regulation, and genetics of bile acid synthesis

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Disruption of the oxysterol 7alpha-hydroxylase gene in mice.

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Beyond intestinal soap--bile acids in metabolic control.

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LXRS and FXR: the yin and yang of cholesterol and fat metabolism

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The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation

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Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1.

21 January 2018

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Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

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The Bile Acid Chenodeoxycholic Acid Increases Human Brown Adipose Tissue Activity.

21 January 2018

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Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut

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Bile acid is a host factor that regulates the composition of the cecal microbiota in rats.

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Diet-induced extinctions in the gut microbiota compound over generations

21 January 2018

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Unexpected evidence for active brown adipose tissue in adult humans

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Identification and importance of brown adipose tissue in adult humans

21 January 2018

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High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity

21 January 2018

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Cold-activated brown adipose tissue in healthy men

21 January 2018

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Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans.

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The changed metabolic world with human brown adipose tissue: therapeutic visions.

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FGF21 Lowers Plasma Triglycerides by Accelerating Lipoprotein Catabolism in White and Brown Adipose Tissues

21 January 2018

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Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes

21 January 2018

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Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling.

21 January 2018

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The brown fat-enriched secreted factor Nrg4 preserves metabolic homeostasis through attenuation of hepatic lipogenesis

21 January 2018

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Metabolic interplay between white, beige, brown adipocytes and the liver

21 January 2018

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Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist

21 January 2018

1 reference

Microbiota prevents cholesterol loss from the body by regulating host gene expression in mice

21 January 2018

1 reference

Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism

21 January 2018

1 reference

Human insulin resistance is associated with increased plasma levels of 12α-hydroxylated bile acids

21 January 2018

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Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus.

21 January 2018

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Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants

21 January 2018

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Faecal microbiota profiles as diagnostic biomarkers in primary sclerosing cholangitis

21 January 2018

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mvabund- anRpackage for model-based analysis of multivariate abundance data

21 January 2018

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A liquid chromatography-tandem mass spectrometry-based method for the simultaneous determination of hydroxy sterols and bile acids

21 January 2018

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De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health

21 January 2018

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Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

21 January 2018

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7 January 2021

inferred from DOI database lookup

Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10-/- mice

1 reference

7 January 2021

inferred from DOI database lookup

Synthetic farnesoid X receptor agonists induce high-density lipoprotein-mediated transhepatic cholesterol efflux in mice and monkeys and prevent atherosclerosis in cholesteryl ester transfer protein transgenic low-density lipoprotein receptor (-/-)

1 reference

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NM.4357

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28604703%20AND%20SRC:MED&resulttype=core&format=json

release_goitdby74rdzrkcob4s6xczst4

22 March 2020

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/goitdby74rdzrkcob4s6xczst4

24 November 2022

mapped directly with Wikidata item

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